Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia X Hu, P Li, Y Guo, H Wang, RK Leak, S Chen, Y Gao, J Chen Stroke 43 (11), 3063-3070, 2012 | 1494 | 2012 |
Microglial and macrophage polarization—new prospects for brain repair X Hu, RK Leak, Y Shi, J Suenaga, Y Gao, P Zheng, J Chen Nature Reviews Neurology 11 (1), 56-64, 2015 | 1311 | 2015 |
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia J Chen, T Nagayama, K Jin, RA Stetler, RL Zhu, SH Graham, RP Simon Journal of Neuroscience 18 (13), 4914-4928, 1998 | 956 | 1998 |
Blood-brain barrier dysfunction and recovery after ischemic stroke X Jiang, AV Andjelkovic, L Zhu, T Yang, MVL Bennett, J Chen, RF Keep, ... Progress in neurobiology 163, 144-171, 2018 | 716 | 2018 |
Programmed cell death in cerebral ischemia SH Graham, J Chen Journal of Cerebral Blood Flow & Metabolism 21 (2), 99-109, 2001 | 686 | 2001 |
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. G Yang, PH Chan, J Chen, E Carlson, SF Chen, P Weinstein, CJ Epstein, ... Stroke 25 (1), 165-170, 1994 | 675 | 1994 |
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection M Zhang, C An, Y Gao, RK Leak, J Chen, F Zhang Progress in neurobiology 100, 30-47, 2013 | 655 | 2013 |
Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures T Nagayama, AD Sinor, RP Simon, J Chen, SH Graham, K Jin, ... Journal of Neuroscience 19 (8), 2987-2995, 1999 | 613 | 1999 |
In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis G Cao, W Pei, H Ge, Q Liang, Y Luo, FR Sharp, A Lu, R Ran, SH Graham, ... Journal of Neuroscience 22 (13), 5423-5431, 2002 | 587 | 2002 |
Microglia/macrophage polarization dynamics in white matter after traumatic brain injury G Wang, J Zhang, X Hu, L Zhang, L Mao, X Jiang, AKF Liou, RK Leak, ... Journal of Cerebral Blood Flow & Metabolism 33 (12), 1864-1874, 2013 | 479 | 2013 |
Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration PS Vosler, CS Brennan, J Chen Molecular neurobiology 38 (1), 78-100, 2008 | 459 | 2008 |
Stress proteins and tolerance to focal cerebral ischemia J Chen, SH Graham, RL Zhu, RP Simon Journal of Cerebral Blood Flow & Metabolism 16 (4), 566-577, 1996 | 453 | 1996 |
Ischemic tolerance in the brain J Chen, R Simon Neurology 48 (2), 306-311, 1997 | 417 | 1997 |
Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia M Nakayama, K Uchimura, RL Zhu, T Nagayama, ME Rose, RA Stetler, ... Proceedings of the National Academy of Sciences 95 (18), 10954-10959, 1998 | 410 | 1998 |
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways AKF Liou, RS Clark, DC Henshall, XM Yin, J Chen Progress in neurobiology 69 (2), 103-142, 2003 | 408 | 2003 |
Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death J Chen, K Jin, M Chen, W Pei, K Kawaguchi, DA Greenberg, RP Simon Journal of neurochemistry 69 (1), 232-245, 1997 | 398 | 1997 |
Cerebral vascular disease and neurovascular injury in ischemic stroke X Hu, TM De Silva, J Chen, FM Faraci Circulation research 120 (3), 449-471, 2017 | 396 | 2017 |
Interleukin-4 is essential for microglia/macrophage M2 polarization and long-term recovery after cerebral ischemia X Liu, J Liu, S Zhao, H Zhang, W Cai, M Cai, X Ji, RK Leak, Y Gao, J Chen, ... Stroke 47 (2), 498-504, 2016 | 385 | 2016 |
Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury G Cao, J Xing, X Xiao, AKF Liou, Y Gao, XM Yin, RSB Clark, SH Graham, ... Journal of Neuroscience 27 (35), 9278-9293, 2007 | 377 | 2007 |
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury RSB CLARK, PM KOCHANEK, M CHEN, SC WATKINS, DW MARION, ... The FASEB journal 13 (8), 813-821, 1999 | 362 | 1999 |