关注
David E Martin
David E Martin
President & CEO, TrippBio,Inc.
在 trippbio.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS
HJD O’Brien WA, Hartigan PH, Martin D, Esinhart J, Hill A, Benoit S, Rubin M ...
New England Journal of Medicine 334, 426-31, 1996
9341996
PA-457: a potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing
F Li, R Goila-Gaur, K Salzwedel, NR Kilgore, M Reddick, C Matallana, ...
Proceedings of the National Academy of Sciences 100 (23), 13555-13560, 2003
5392003
Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid …
PF Smith, A Ogundele, A Forrest, J Wilton, K Salzwedel, J Doto, ...
Antimicrobial agents and chemotherapy 51 (10), 3574-3581, 2007
2512007
Pharmacokinetics of lamivudine administered alone and with trimethoprim‐sulfamethoxazole
KHP Moore, GJ Yuen, RH Raasch, JJ Eron, D Martin, PK Mydlow, ...
Clinical Pharmacology & Therapeutics 59 (5), 550-558, 1996
1471996
Bevirimat: a novel maturation inhibitor for the treatment of HIV-1 infection
DE Martin, K Salzwedel, GP Allaway
Antiviral Chemistry and Chemotherapy 19 (3), 107-113, 2008
1122008
Morning Spot and 24‐Hour Urinary 6β‐Hydroxycortisol to Cortisol Ratios: Intraindividual Variability and Correlation under Basal Conditions and Conditions of CYP 3A4 Induction
JQ Tran, SJ Kovacs, TS McIntosh, HM Davis, DE Martin
The Journal of Clinical Pharmacology 39 (5), 487-494, 1999
1071999
Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers
DJ Kazierad, DE Martin, RA Blum, DM Tenero, B Ilson, SC Boike, ...
Clinical Pharmacology & Therapeutics 62 (4), 417-425, 1997
1051997
Maturation inhibitors: a new therapeutic class targets the virus structure.
K Salzwedel, DE Martin, M Sakalian
AIDS reviews 9 (3), 162-172, 2007
992007
Safety, efficacy, and pharmacokinetics of TBR-652, a CCR5/CCR2 antagonist, in HIV-1–infected, treatment-experienced, CCR5 antagonist–naive subjects
J Lalezari, J Gathe, C Brinson, M Thompson, C Cohen, E Dejesus, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 57 (2), 118-125, 2011
882011
Safety and pharmacokinetics of Bevirimat (PA-457), a novel inhibitor of human immunodeficiency virus maturation, in healthy volunteers
DE Martin, R Blum, J Wilton, J Doto, H Galbraith, GL Burgess, PC Smith, ...
Antimicrobial Agents and Chemotherapy 51 (9), 3063-3066, 2007
862007
Determinants of activity of the HIV-1 maturation inhibitor PA-457
F Li, D Zoumplis, C Matallana, NR Kilgore, M Reddick, AS Yunus, ...
Virology 356 (1-2), 217-224, 2006
812006
Urinary excretion of 6β‐hydroxycortisol as an in vivo marker for CYP3A induction: applications and recommendations
SJ Kovacs, DE Martin, DE Everitt, SD Patterson, DK Jorkasky
Clinical Pharmacology & Therapeutics 63 (6), 617-622, 1998
781998
The discovery of a class of novel HIV-1 maturation inhibitors and their potential in the therapy of HIV
D Yu, CT Wild, DE Martin, SL Morris-Natschke, CH Chen, GP Allaway, ...
Expert opinion on investigational drugs 14 (6), 681-693, 2005
662005
Pharmacokinetics of intravenously and orally administered eprosartan in healthy males: absolute bioavailability and effect of food
D Tenero, D Martin, B Ilson, J Jushchyshyn, S Boike, D Lundberg, ...
Biopharmaceutics & drug disposition 19 (6), 351-356, 1998
611998
Pharmacokinetics and pharmacodynamics of TBR-652, a novel CCR5 antagonist, in HIV-1-infected, antiretroviral treatment-experienced, CCR5 antagonist-naive patients
JF Marier, MM Trinh, LH Pheng, SM Palleja, DE Martin
Antimicrobial agents and chemotherapy 55 (6), 2768-2774, 2011
572011
Alkyl amine bevirimat derivatives are potent and broadly active HIV-1 maturation inhibitors
E Urano, SD Ablan, R Mandt, GT Pauly, DM Sigano, JP Schneider, ...
Antimicrobial agents and chemotherapy 60 (1), 190-197, 2016
532016
Potent activity of the HIV-1 maturation inhibitor bevirimat in SCID-hu Thy/Liv mice
CA Stoddart, P Joshi, B Sloan, JC Bare, PC Smith, GP Allaway, CT Wild, ...
PLoS One 2 (11), e1251, 2007
532007
Multiple-dose pharmacokinetics and safety of bevirimat, a novel inhibitor of HIV maturation, in healthy volunteers
DE Martin, R Blum, J Doto, H Galbraith, C Ballow
Clinical pharmacokinetics 46, 589-598, 2007
532007
HIV-1 Gag polymorphisms determine treatment response to bevirimat (PA-457)
S McCallister, J Lalezari, G Richmond, M Thompson, R Harrigan, D Martin, ...
Antivir Ther 13 (Suppl 3), A10, 2008
522008
Pharmacokinetics and protein binding of eprosartan in healthy volunteers and in patients with varying degrees of renal impairment
DE Martin, MC Chapelsky, B Ilson, D Tenero, SC Boike, N Zariffa, ...
The Journal of Clinical Pharmacology 38 (2), 129-137, 1998
501998
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