Sarcoma treatment in the era of molecular medicine TGP Grünewald, M Alonso, S Avnet, A Banito, S Burdach, F Cidre‐Aranaz, ... EMBO molecular medicine 12 (11), e11131, 2020 | 233 | 2020 |
Osteosarcoma: cells‐of‐origin, cancer stem cells, and targeted therapies A Abarrategi, J Tornin, L Martinez-Cruzado, A Hamilton, ... Stem cells international 2016 (1), 3631764, 2016 | 233 | 2016 |
Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress R Rodriguez, M Meuth Molecular biology of the cell 17 (1), 402-412, 2006 | 229 | 2006 |
Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool J Garcia‐Castro, C Trigueros, J Madrenas, JA Perez‐Simon, R Rodriguez, ... Journal of cellular and molecular medicine 12 (6b), 2552-2565, 2008 | 222 | 2008 |
Bone microenvironment signals in osteosarcoma development A Alfranca, L Martinez-Cruzado, J Tornin, A Abarrategi, T Amaral, ... Cellular and Molecular Life Sciences 72, 3097-3113, 2015 | 212 | 2015 |
Modeling sarcomagenesis using multipotent mesenchymal stem cells R Rodriguez, R Rubio, P Menendez Cell research 22 (1), 62-77, 2012 | 165 | 2012 |
Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory … L Sánchez, I Gutierrez-Aranda, G Ligero, R Rubio, M Muñoz-López, ... Stem cells 29 (2), 251-262, 2011 | 161 | 2011 |
Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene P Menendez, P Catalina, R Rodríguez, GJ Melen, C Bueno, M Arriero, ... Journal of Experimental Medicine 206 (13), 3131-3141, 2009 | 156 | 2009 |
ATR and Chk1 suppress a caspase-3–dependent apoptotic response following DNA replication stress K Myers, ME Gagou, P Zuazua-Villar, R Rodriguez, M Meuth PLoS genetics 5 (1), e1000324, 2009 | 151 | 2009 |
Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells R Rodriguez, R Rubio, M Masip, P Catalina, A Nieto, T de la Cueva, ... Neoplasia 11 (4), 397-IN9, 2009 | 132 | 2009 |
Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo R Rubio, J García-Castro, I Gutiérrez-Aranda, J Paramio, M Santos, ... Cancer research 70 (10), 4185-4194, 2010 | 122 | 2010 |
Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells R Rubio, A Abarrategi, J Garcia‐Castro, L Martinez‐Cruzado, C Suarez, ... Stem cells 32 (5), 1136-1148, 2014 | 109 | 2014 |
Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement C Bueno, R Montes, P Catalina, R Rodriguez, P Menendez Leukemia 25 (3), 400-410, 2011 | 102 | 2011 |
The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development R Rubio, I Gutierrez-Aranda, AI Sáez-Castillo, A Labarga, M Rosu-Myles, ... Oncogene 32 (41), 4970-4980, 2013 | 101 | 2013 |
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors V Ramos-Mejía, R Montes, C Bueno, V Ayllón, PJ Real, R Rodríguez, ... PloS one 7 (4), e35824, 2012 | 92 | 2012 |
Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation R Rodriguez, J Tornin, C Suarez, A Astudillo, R Rubio, C Yauk, A Williams, ... Stem cells 31 (10), 2061-2072, 2013 | 83 | 2013 |
Pyruvate plays a main role in the antitumoral selectivity of cold atmospheric plasma in osteosarcoma J Tornin, M Mateu-Sanz, A Rodríguez, C Labay, R Rodríguez, C Canal Scientific reports 9 (1), 10681, 2019 | 81 | 2019 |
Sarcoma stem cell heterogeneity J Hatina, M Kripnerova, K Houfkova, M Pesta, J Kuncova, J Sana, O Slaby, ... Stem Cells Heterogeneity-Novel Concepts, 95-118, 2019 | 72 | 2019 |
FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells R Rodriguez, R Rubio, I Gutierrez-Aranda, GJ Melen, C Elosua, ... Stem Cells 29 (2), 179-192, 2011 | 72 | 2011 |
Inactivation of p53 in human keratinocytes leads to squamous differentiation and shedding via replication stress and mitotic slippage A Freije, R Molinuevo, L Ceballos, M Cagigas, P Alonso-Lecue, ... Cell reports 9 (4), 1349-1360, 2014 | 65 | 2014 |