| Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus CT De Souza, EP Araujo, S Bordin, R Ashimine, RL Zollner, AC Boschero, ... Endocrinology 146 (10), 4192-4199, 2005 | 1317 | 2005 |
| Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1212 | 2009 |
| Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance DML Tsukumo, MA Carvalho-Filho, JBC Carvalheira, PO Prada, ... Diabetes 56 (8), 1986-1998, 2007 | 1063 | 2007 |
| Linking gut microbiota and inflammation to obesity and insulin resistance MJA Saad, A Santos, PO Prada Physiology 31 (4), 283-293, 2016 | 780 | 2016 |
| TyG index performs better than HOMA in a Brazilian population: a hyperglycemic clamp validated study ACJ Vasques, FS Novaes, MS de Oliveira, JRM Souza, A Yamanaka, ... Diabetes research and clinical practice 93 (3), e98-e100, 2011 | 514 | 2011 |
| High-fat diet induces apoptosis of hypothalamic neurons JC Moraes, A Coope, J Morari, DE Cintra, EA Roman, JR Pauli, ... PloS one 4 (4), e5045, 2009 | 498 | 2009 |
| Cross-talk between the insulin and angiotensin signaling systems. LA Velloso, F Folli, XJ Sun, MF White, MJ Saad, CR Kahn Proceedings of the National Academy of Sciences 93 (22), 12490-12495, 1996 | 487 | 1996 |
| IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition ER Ropelle, MB Flores, DE Cintra, GZ Rocha, JR Pauli, J Morari, ... PLoS biology 8 (8), e1000465, 2010 | 462 | 2010 |
| Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. MJ Saad, F Folli, JA Kahn, CR Kahn The Journal of clinical investigation 92 (4), 2065-2072, 1993 | 425 | 1993 |
| Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity DE Cintra, ER Ropelle, JC Moraes, JR Pauli, J Morari, CT de Souza, ... PloS one 7 (1), e30571, 2012 | 414 | 2012 |
| Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. MJ Saad, E Araki, M Miralpeix, PL Rothenberg, MF White, CR Kahn The Journal of clinical investigation 90 (5), 1839-1849, 1992 | 407 | 1992 |
| Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice BM Carvalho, D Guadagnini, DML Tsukumo, AA Schenka, P Latuf-Filho, ... Diabetologia 55, 2823-2834, 2012 | 355 | 2012 |
| Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth GZ Rocha, MM Dias, ER Ropelle, F Osório-Costa, FA Rossato, ... Clinical cancer research 17 (12), 3993-4005, 2011 | 351 | 2011 |
| S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance MA Carvalho-Filho, M Ueno, SM Hirabara, AB Seabra, JBC Carvalheira, ... Diabetes 54 (4), 959-967, 2005 | 336 | 2005 |
| Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice AM Caricilli, PK Picardi, LL de Abreu, M Ueno, PO Prada, ER Ropelle, ... PLoS biology 9 (12), e1001212, 2011 | 334 | 2011 |
| Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat. F Folli, MJ Saad, JM Backer, CR Kahn Journal of Biological Chemistry 267 (31), 22171-22177, 1992 | 321 | 1992 |
| The role of gut microbiota on insulin resistance AM Caricilli, MJA Saad Nutrients 5 (3), 829-851, 2013 | 298 | 2013 |
| Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. F Folli, MJ Saad, JM Backer, CR Kahn The Journal of clinical investigation 92 (4), 1787-1794, 1993 | 294 | 1993 |
| TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation LA Velloso, F Folli, MJ Saad Endocrine reviews 36 (3), 245-271, 2015 | 286 | 2015 |
| Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice RA Bagarolli, N Tobar, AG Oliveira, TG Araújo, BM Carvalho, GZ Rocha, ... The Journal of nutritional biochemistry 50, 16-25, 2017 | 264 | 2017 |
