A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression CA Zarate, JB Singh, PJ Carlson, NE Brutsche, R Ameli, DA Luckenbaugh, ... Archives of general psychiatry 63 (8), 856-864, 2006 | 3964 | 2006 |
Efficacy and safety of intranasal esketamine adjunctive to oral antidepressant therapy in treatment-resistant depression: a randomized clinical trial EJ Daly, JB Singh, M Fedgchin, K Cooper, P Lim, RC Shelton, ME Thase, ... JAMA psychiatry 75 (2), 139-148, 2018 | 643 | 2018 |
Efficacy and safety of flexibly dosed esketamine nasal spray combined with a newly initiated oral antidepressant in treatment-resistant depression: a randomized double-blind … V Popova, EJ Daly, M Trivedi, K Cooper, R Lane, P Lim, C Mazzucco, ... American Journal of Psychiatry 176 (6), 428-438, 2019 | 535 | 2019 |
A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression JB Singh, M Fedgchin, EJ Daly, P De Boer, K Cooper, P Lim, C Pinter, ... American Journal of Psychiatry 173 (8), 816-826, 2016 | 519 | 2016 |
Efficacy and safety of intranasal esketamine for the rapid reduction of symptoms of depression and suicidality in patients at imminent risk for suicide: results of a double … CM Canuso, JB Singh, M Fedgchin, L Alphs, R Lane, P Lim, C Pinter, ... American journal of psychiatry 175 (7), 620-630, 2018 | 478 | 2018 |
A double-blind, placebo-controlled study of memantine in the treatment of major depression CA Zarate Jr, JB Singh, JA Quiroz, G De Jesus, KK Denicoff, ... American Journal of Psychiatry 163 (1), 153-155, 2006 | 470 | 2006 |
Efficacy of esketamine nasal spray plus oral antidepressant treatment for relapse prevention in patients with treatment-resistant depression: a randomized clinical trial EJ Daly, MH Trivedi, A Janik, H Li, Y Zhang, X Li, R Lane, P Lim, AR Duca, ... JAMA psychiatry 76 (9), 893-903, 2019 | 463 | 2019 |
Pramipexole for bipolar II depression: a placebo-controlled proof of concept study CA Zarate Jr, JL Payne, J Singh, JA Quiroz, DA Luckenbaugh, ... Biological psychiatry 56 (1), 54-60, 2004 | 428 | 2004 |
Intravenous esketamine in adult treatment-resistant depression: a double-blind, double-randomization, placebo-controlled study JB Singh, M Fedgchin, E Daly, L Xi, C Melman, G De Bruecker, A Tadic, ... Biological psychiatry 80 (6), 424-431, 2016 | 421 | 2016 |
Efficacy and safety of fixed-dose esketamine nasal spray combined with a new oral antidepressant in treatment-resistant depression: results of a randomized, double-blind … M Fedgchin, M Trivedi, EJ Daly, R Melkote, R Lane, P Lim, D Vitagliano, ... International Journal of Neuropsychopharmacology 22 (10), 616-630, 2019 | 337 | 2019 |
Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder CA Zarate Jr, J Singh, HK Manji Biological psychiatry 59 (11), 1006-1020, 2006 | 311 | 2006 |
An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression CA Zarate Jr, JA Quiroz, JB Singh, KD Denicoff, G De Jesus, ... Biological Psychiatry 57 (4), 430-432, 2005 | 309 | 2005 |
Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers TD Gould, JA Quiroz, J Singh, CA Zarate, HK Manji Molecular psychiatry 9 (8), 734-755, 2004 | 302 | 2004 |
The underlying neurobiology of bipolar disorder HK Manji, JA Quiroz, JL Payne, J Singh, BP Lopes, JS Viegas, CA Zarate World Psychiatry 2 (3), 136, 2003 | 251 | 2003 |
Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study CA Zarate Jr, JB Singh, PJ Carlson, J Quiroz, L Jolkovsky, ... Bipolar disorders 9 (6), 561-570, 2007 | 242 | 2007 |
Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system CA Zarate Jr, J Du, J Quiroz, NA Gray, KD Denicoff, J Singh, DS Charney, ... Annals of the New York Academy of Sciences 1003 (1), 273-291, 2003 | 237 | 2003 |
Efficacy and safety of esketamine nasal spray plus an oral antidepressant in elderly patients with treatment-resistant depression—TRANSFORM-3 R Ochs-Ross, EJ Daly, Y Zhang, R Lane, P Lim, RL Morrison, D Hough, ... The American Journal of Geriatric Psychiatry 28 (2), 121-141, 2020 | 233 | 2020 |
Esketamine nasal spray plus oral antidepressant in patients with treatment-resistant depression: assessment of long-term safety in a phase 3, open-label study (SUSTAIN-2) E Wajs, L Aluisio, R Holder, EJ Daly, R Lane, P Lim, JE George, ... The Journal of clinical psychiatry 81 (3), 10773, 2020 | 209 | 2020 |
Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2 D Sakry, A Neitz, J Singh, R Frischknecht, D Marongiu, F Binamé, ... PLoS biology 12 (11), e1001993, 2014 | 195 | 2014 |
Neural circuitry and neuroplasticity in mood disorders: insights for novel therapeutic targets PJ Carlson, JB Singh, CA Zarate Jr, WC Drevets, HK Manji NeuroRx 3 (1), 22-41, 2006 | 182 | 2006 |