| Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy A Sheih, V Voillet, LA Hanafi, HA DeBerg, M Yajima, R Hawkins, V Gersuk, ... Nature communications 11 (1), 219, 2020 | 200 | 2020 |
| Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations R Shahbazi, G Sghia-Hughes, JL Reid, S Kubek, KG Haworth, O Humbert, ... Nature materials 18 (10), 1124-1132, 2019 | 146 | 2019 |
| Role of high mobility group (HMG) chromatin proteins in DNA repair R Reeves, JE Adair DNA repair 4 (8), 926-938, 2005 | 145 | 2005 |
| Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells JL Gori, JM Butler, YY Chan, D Chandrasekaran, MG Poulos, M Ginsberg, ... The Journal of clinical investigation 125 (3), 1243-1254, 2015 | 126 | 2015 |
| Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates BC Beard, GD Trobridge, C Ironside, JS McCune, JE Adair, HP Kiem The Journal of clinical investigation 120 (7), 2345-2354, 2010 | 123 | 2010 |
| Extended survival of glioblastoma patients after chemoprotective HSC gene therapy JE Adair, BC Beard, GD Trobridge, T Neff, JK Rockhill, DL Silbergeld, ... Science translational medicine 4 (133), 133ra57-133ra57, 2012 | 120 | 2012 |
| Therapeutically relevant engraftment of a CRISPR-Cas9–edited HSC-enriched population with HbF reactivation in nonhuman primates O Humbert, S Radtke, C Samuelson, RR Carrillo, AM Perez, SS Reddy, ... Science translational medicine 11 (503), eaaw3768, 2019 | 109 | 2019 |
| A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates S Radtke, JE Adair, MA Giese, YY Chan, ZK Norgaard, M Enstrom, ... Science translational medicine 9 (414), eaan1145, 2017 | 106 | 2017 |
| Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells CX Wang, BD Sather, X Wang, J Adair, I Khan, S Singh, S Lang, A Adams, ... Blood, The Journal of the American Society of Hematology 124 (6), 913-923, 2014 | 102 | 2014 |
| Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients JE Adair, SK Johnston, MM Mrugala, BC Beard, LA Guyman, AL Baldock, ... The Journal of clinical investigation 124 (9), 4082-4092, 2014 | 100 | 2014 |
| Point-of-care and/or portable platform for gene therapy JE Adair, HP Kiem US Patent 10,350,245, 2019 | 95 | 2019 |
| Inhibition of nucleotide excision repair by high mobility group protein HMGA1 JE Adair, YH Kwon, GA Dement, MJ Smerdon, R Reeves Journal of Biological Chemistry 280 (37), 32184-32192, 2005 | 71 | 2005 |
| Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS CW Peterson, KG Haworth, BP Burke, P Polacino, KK Norman, JE Adair, ... Molecular Therapy-Methods & Clinical Development 3, 2016 | 63 | 2016 |
| Safeguarding nonhuman primate iPS cells with suicide genes B Zhong, KL Watts, JL Gori, ME Wohlfahrt, J Enssle, JE Adair, HP Kiem Molecular Therapy 19 (9), 1667-1675, 2011 | 62 | 2011 |
| Plerixafor+G-CSF–mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy G Karponi, N Psatha, CW Lederer, JE Adair, F Zervou, N Zogas, ... Blood, The Journal of the American Society of Hematology 126 (5), 616-619, 2015 | 58 | 2015 |
| Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting J Tolar, JE Adair, M Antoniou, CC Bartholomae, PS Becker, BR Blazar, ... Molecular Therapy 19 (7), 1193-1198, 2011 | 57 | 2011 |
| Inter-α-trypsin inhibitor promotes bronchial epithelial repair after injury through vitronectin binding JE Adair, V Stober, M Sobhany, L Zhuo, JD Roberts, M Negishi, K Kimata, ... Journal of Biological Chemistry 284 (25), 16922-16930, 2009 | 53 | 2009 |
| Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector PS Becker, JA Taylor, GD Trobridge, X Zhao, BC Beard, S Chien, J Adair, ... Gene therapy 17 (10), 1244-1252, 2010 | 48 | 2010 |
| Efficient generation, purification, and expansion of CD34+ hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells JL Gori, D Chandrasekaran, JP Kowalski, JE Adair, BC Beard, ... Blood, The Journal of the American Society of Hematology 120 (13), e35-e44, 2012 | 44 | 2012 |
| Lessons learned from two decades of clinical trial experience in gene therapy for Fanconi anemia J E Adair, J Sevilla, C Diaz de Heredia, P S Becker, HP Kiem, J Bueren Current Gene Therapy 16 (5), 338-348, 2016 | 43 | 2016 |
