The role of microglia and macrophages in glioma maintenance and progression D Hambardzumyan, DH Gutmann, H Kettenmann Nature neuroscience 19 (1), 20-27, 2016 | 1416 | 2016 |
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells AM Bleau, D Hambardzumyan, T Ozawa, EI Fomchenko, JT Huse, ... Cell stem cell 4 (3), 226-235, 2009 | 952 | 2009 |
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo JT Huse, C Brennan, D Hambardzumyan, B Wee, J Pena, ... Genes & development 23 (11), 1327-1337, 2009 | 661 | 2009 |
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations C Brennan, H Momota, D Hambardzumyan, T Ozawa, A Tandon, ... PloS one 4 (11), e7752, 2009 | 649 | 2009 |
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells N Charles, T Ozawa, M Squatrito, AM Bleau, CW Brennan, ... Cell stem cell 6 (2), 141-152, 2010 | 611 | 2010 |
Cellular and molecular identity of tumor-associated macrophages in glioblastoma Z Chen, X Feng, CJ Herting, VA Garcia, K Nie, WW Pong, R Rasmussen, ... Cancer research 77 (9), 2266-2278, 2017 | 564 | 2017 |
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo D Hambardzumyan, OJ Becher, MK Rosenblum, PP Pandolfi, ... Genes & development 22 (4), 436-448, 2008 | 553 | 2008 |
Ly6Chi monocytes provide a link between antibiotic-induced changes in gut microbiota and adult hippocampal neurogenesis L Möhle, D Mattei, MM Heimesaat, S Bereswill, A Fischer, M Alutis, ... Cell reports 15 (9), 1945-1956, 2016 | 446 | 2016 |
Glioblastoma: defining tumor niches D Hambardzumyan, G Bergers Trends in cancer 1 (4), 252-265, 2015 | 439 | 2015 |
Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1 F Szulzewsky, A Pelz, X Feng, M Synowitz, D Markovic, T Langmann, ... PloS one 10 (2), e0116644, 2015 | 413 | 2015 |
Immune microenvironment in glioblastoma subtypes Z Chen, D Hambardzumyan Frontiers in immunology 9, 1004, 2018 | 381 | 2018 |
Seeding and propagation of untransformed mouse mammary cells in the lung K Podsypanina, YCN Du, M Jechlinger, LJ Beverly, D Hambardzumyan, ... Science 321 (5897), 1841-1844, 2008 | 369 | 2008 |
Corticosteroids compromise survival in glioblastoma KL Pitter, I Tamagno, K Alikhanyan, A Hosni-Ahmed, SS Pattwell, ... Brain 139 (5), 1458-1471, 2016 | 337 | 2016 |
Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules K Leder, K Pitter, Q LaPlant, D Hambardzumyan, BD Ross, TA Chan, ... Cell 156 (3), 603-616, 2014 | 282 | 2014 |
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3 OA Guryanova, Q Wu, L Cheng, JD Lathia, Z Huang, J Yang, ... Cancer cell 19 (4), 498-511, 2011 | 275 | 2011 |
Modeling adult gliomas using RCAS/t-va technology D Hambardzumyan, NM Amankulor, KY Helmy, OJ Becher, EC Holland Translational oncology 2 (2), 89-IN6, 2009 | 271 | 2009 |
Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation NM Amankulor, D Hambardzumyan, SM Pyonteck, OJ Becher, JA Joyce, ... Journal of Neuroscience 29 (33), 10299-10308, 2009 | 241 | 2009 |
Radiation resistance and stem-like cells in brain tumors D Hambardzumyan, M Squartro, EC Holland Cancer cell 10 (6), 454-456, 2006 | 236 | 2006 |
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response FJ Núñez, FM Mendez, P Kadiyala, MS Alghamri, MG Savelieff, ... Science translational medicine 11 (479), eaaq1427, 2019 | 223 | 2019 |
Gli activity correlates with tumor grade in platelet-derived growth factor–induced gliomas OJ Becher, D Hambardzumyan, EI Fomchenko, H Momota, L Mainwaring, ... Cancer research 68 (7), 2241-2249, 2008 | 217 | 2008 |