Synthetic genetic polymers capable of heredity and evolution VB Pinheiro, AI Taylor, C Cozens, M Abramov, M Renders, S Zhang, ... Science 336 (6079), 341-344, 2012 | 777 | 2012 |
Catalysts from synthetic genetic polymers AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ... Nature 518 (7539), 427-430, 2015 | 292 | 2015 |
Beyond DNA and RNA: the expanding toolbox of synthetic genetics AI Taylor, G Houlihan, P Holliger Cold Spring Harbor perspectives in biology 11 (6), a032490, 2019 | 198* | 2019 |
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids S Arangundy-Franklin, AI Taylor, BT Porebski, V Genna, S Peak-Chew, ... Nature chemistry 11 (6), 533-542, 2019 | 84 | 2019 |
The crystal structure of an avian IgY-Fc fragment reveals conservation with both mammalian IgG and IgE AI Taylor, SM Fabiane, BJ Sutton, RA Calvert Biochemistry 48 (3), 558-562, 2009 | 72 | 2009 |
Avian IgY binds to a monocyte receptor with IgG-like kinetics despite an IgE-like structure AI Taylor, HJ Gould, BJ Sutton, RA Calvert Journal of Biological Chemistry 283 (24), 16384-16390, 2008 | 67 | 2008 |
Nanostructures from synthetic genetic polymers AI Taylor, F Beuron, SY Peak‐Chew, EP Morris, P Herdewijn, P Holliger ChemBioChem 17 (12), 1107-1110, 2016 | 63 | 2016 |
Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers AI Taylor, P Holliger Nature Protocols 10 (10), 1625-1642, 2015 | 55 | 2015 |
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity G Houlihan, S Arangundy-Franklin, BT Porebski, N Subramanian, ... Nature chemistry 12 (8), 683-690, 2020 | 53 | 2020 |
Towards applications of synthetic genetic polymers in diagnosis and therapy AI Taylor, S Arangundy-Franklin, P Holliger Current Opinion in Chemical Biology 22, 79-84, 2014 | 50 | 2014 |
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ... Elife 7, e43022, 2018 | 41 | 2018 |
A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing AI Taylor, CJK Wan, MJ Donde, SY Peak-Chew, P Holliger Nature chemistry 14 (11), 1295-1305, 2022 | 36 | 2022 |
The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL AI Taylor, HJ Gould, BJ Sutton, RA Calvert Immunogenetics 59, 323-328, 2007 | 29 | 2007 |
A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA N Freund, AI Taylor, S Arangundy-Franklin, N Subramanian, ... Nature chemistry 15 (1), 91-100, 2023 | 28 | 2023 |
Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites AI Taylor, BJ Sutton, RA Calvert Developmental & Comparative Immunology 34 (2), 97-101, 2010 | 28 | 2010 |
A monomeric chicken IgY receptor binds IgY with 2: 1 stoichiometry AI Taylor, RL Beavil, BJ Sutton, RA Calvert Journal of Biological Chemistry 284 (36), 24168-24175, 2009 | 28 | 2009 |
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger Angewandte Chemie International Edition 54 (51), 15570-15573, 2015 | 25 | 2015 |
Selecting Fully‐Modified XNA Aptamers Using Synthetic Genetics AI Taylor, P Holliger Current protocols in chemical biology 10 (2), e44, 2018 | 21 | 2018 |
XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection PP Gerber, MJ Donde, NJ Matheson, AI Taylor Nature Communications 13 (1), 6716, 2022 | 12 | 2022 |
On gene silencing by the X10-23 DNAzyme AI Taylor, P Holliger Nature Chemistry 14 (8), 855-858, 2022 | 12 | 2022 |