关注
Alexander I Taylor
Alexander I Taylor
Sir Henry Dale Fellow, Lecturer in Chemical Biology (proleptic), King's College London
在 kcl.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Synthetic genetic polymers capable of heredity and evolution
VB Pinheiro, AI Taylor, C Cozens, M Abramov, M Renders, S Zhang, ...
Science 336 (6079), 341-344, 2012
7772012
Catalysts from synthetic genetic polymers
AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ...
Nature 518 (7539), 427-430, 2015
2922015
Beyond DNA and RNA: the expanding toolbox of synthetic genetics
AI Taylor, G Houlihan, P Holliger
Cold Spring Harbor perspectives in biology 11 (6), a032490, 2019
198*2019
A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids
S Arangundy-Franklin, AI Taylor, BT Porebski, V Genna, S Peak-Chew, ...
Nature chemistry 11 (6), 533-542, 2019
842019
The crystal structure of an avian IgY-Fc fragment reveals conservation with both mammalian IgG and IgE
AI Taylor, SM Fabiane, BJ Sutton, RA Calvert
Biochemistry 48 (3), 558-562, 2009
722009
Avian IgY binds to a monocyte receptor with IgG-like kinetics despite an IgE-like structure
AI Taylor, HJ Gould, BJ Sutton, RA Calvert
Journal of Biological Chemistry 283 (24), 16384-16390, 2008
672008
Nanostructures from synthetic genetic polymers
AI Taylor, F Beuron, SY Peak‐Chew, EP Morris, P Herdewijn, P Holliger
ChemBioChem 17 (12), 1107-1110, 2016
632016
Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers
AI Taylor, P Holliger
Nature Protocols 10 (10), 1625-1642, 2015
552015
Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity
G Houlihan, S Arangundy-Franklin, BT Porebski, N Subramanian, ...
Nature chemistry 12 (8), 683-690, 2020
532020
Towards applications of synthetic genetic polymers in diagnosis and therapy
AI Taylor, S Arangundy-Franklin, P Holliger
Current Opinion in Chemical Biology 22, 79-84, 2014
502014
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination
H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ...
Elife 7, e43022, 2018
412018
A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing
AI Taylor, CJK Wan, MJ Donde, SY Peak-Chew, P Holliger
Nature chemistry 14 (11), 1295-1305, 2022
362022
The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL
AI Taylor, HJ Gould, BJ Sutton, RA Calvert
Immunogenetics 59, 323-328, 2007
292007
A two-residue nascent-strand steric gate controls synthesis of 2′-O-methyl- and 2′-O-(2-methoxyethyl)-RNA
N Freund, AI Taylor, S Arangundy-Franklin, N Subramanian, ...
Nature chemistry 15 (1), 91-100, 2023
282023
Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites
AI Taylor, BJ Sutton, RA Calvert
Developmental & Comparative Immunology 34 (2), 97-101, 2010
282010
A monomeric chicken IgY receptor binds IgY with 2: 1 stoichiometry
AI Taylor, RL Beavil, BJ Sutton, RA Calvert
Journal of Biological Chemistry 284 (36), 24168-24175, 2009
282009
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages
C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger
Angewandte Chemie International Edition 54 (51), 15570-15573, 2015
252015
Selecting Fully‐Modified XNA Aptamers Using Synthetic Genetics
AI Taylor, P Holliger
Current protocols in chemical biology 10 (2), e44, 2018
212018
XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection
PP Gerber, MJ Donde, NJ Matheson, AI Taylor
Nature Communications 13 (1), 6716, 2022
122022
On gene silencing by the X10-23 DNAzyme
AI Taylor, P Holliger
Nature Chemistry 14 (8), 855-858, 2022
122022
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