Targeting p38 MAPK pathway for the treatment of Alzheimer's disease L Munoz, AJ Ammit Neuropharmacology 58 (3), 561-568, 2010 | 418 | 2010 |
Targeting cancer cell dormancy A Recasens, L Munoz Trends in pharmacological sciences 40 (2), 128-141, 2019 | 268 | 2019 |
A novel p38α MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse … L Munoz, HR Ranaivo, SM Roy, W Hu, JM Craft, LK McNamara, LW Chico, ... Journal of neuroinflammation 4, 1-14, 2007 | 259 | 2007 |
Interleukins in glioblastoma pathophysiology: implications for therapy YT Yeung, KL McDonald, T Grewal, L Munoz British journal of pharmacology 168 (3), 591-606, 2013 | 230 | 2013 |
DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications R Abbassi, TG Johns, M Kassiou, L Munoz Pharmacology & therapeutics 151, 87-98, 2015 | 148 | 2015 |
Non-kinase targets of protein kinase inhibitors L Munoz Nature Reviews Drug Discovery 16 (6), 424-440, 2017 | 123 | 2017 |
Targeting p38 or MK2 enhances the anti-leukemic activity of Smac-mimetics N Lalaoui, K Hänggi, G Brumatti, D Chau, NYN Nguyen, L Vasilikos, ... Cancer cell 29 (2), 145-158, 2016 | 121 | 2016 |
Mitogen-activated protein kinase–activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting FMS Gurgis, W Ziaziaris, L Munoz Molecular pharmacology 85 (2), 345-356, 2014 | 101 | 2014 |
Development of a novel therapeutic suppressor of brain proinflammatory cytokine up-regulation that attenuates synaptic dysfunction and behavioral deficits W Hu, HR Ranaivo, SM Roy, HA Behanna, LK Wing, L Munoz, L Guo, ... Bioorganic & medicinal chemistry letters 17 (2), 414-418, 2007 | 98 | 2007 |
p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells YT Yeung, NS Bryce, S Adams, N Braidy, M Konayagi, KL McDonald, ... Journal of neuro-oncology 109, 35-44, 2012 | 94 | 2012 |
The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells FMS Gurgis, YT Yeung, MXM Tang, B Heng, M Buckland, AJ Ammit, ... Oncogene 34 (22), 2934-2942, 2015 | 83 | 2015 |
Histone lysine demethylases and their functions in cancer J Sterling, SV Menezes, RH Abbassi, L Munoz International Journal of Cancer 148 (10), 2375-2388, 2021 | 67 | 2021 |
Structural optimization and pharmacological evaluation of inhibitors targeting dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) and CDC-like kinases (CLK) in … Q Zhou, AF Phoa, RH Abbassi, M Hoque, TA Reekie, JS Font, RM Ryan, ... Journal of Medicinal Chemistry 60 (5), 2052-2070, 2017 | 51 | 2017 |
Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle L Munoz, EE Ramsay, M Manetsch, Q Ge, C Peifer, S Laufer, AJ Ammit European journal of pharmacology 635 (1-3), 212-218, 2010 | 40 | 2010 |
Development and biological evaluation of a photoactivatable small molecule microtubule-targeting agent A Döbber, AF Phoa, RH Abbassi, BW Stringer, BW Day, TG Johns, ... ACS medicinal chemistry letters 8 (4), 395-400, 2017 | 37 | 2017 |
Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation L Munoz, ME Kavanagh, AF Phoa, B Heng, N Dzamko, EJ Chen, ... European Journal of Medicinal Chemistry 95, 29-34, 2015 | 35 | 2015 |
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells A Recasens, SJ Humphrey, M Ellis, M Hoque, RH Abbassi, B Chen, ... Cell death discovery 7 (1), 81, 2021 | 31 | 2021 |
Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists J O'Brien-Brown, A Jackson, TA Reekie, ML Barron, EL Werry, P Schiavini, ... European Journal of Medicinal Chemistry 130, 433-439, 2017 | 31 | 2017 |
Kinase targets in CNS drug discovery H Gunosewoyo, L Yu, L Munoz, M Kassiou Future Medicinal Chemistry 9 (3), 303-314, 2017 | 29 | 2017 |
Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells L Munoz, YT Yeung, T Grewal Cancer biology & therapy 17 (4), 355-363, 2016 | 27 | 2016 |