Function and mechanism of zinc metalloenzymes KA McCall, C Huang, CA Fierke The Journal of nutrition 130 (5), 1437S-1446S, 2000 | 1366 | 2000 |
Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli CA Fierke, KA Johnson, SJ Benkovic Biochemistry 26 (13), 4085-4092, 1987 | 615 | 1987 |
Carbonic anhydrase: evolution of the zinc binding site by nature and by design DW Christianson, CA Fierke Accounts of Chemical Research 29 (7), 331-339, 1996 | 582 | 1996 |
Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli T Ogura, K Inoue, T Tatsuta, T Suzaki, K Karata, K Young, LH Su, ... Molecular microbiology 31 (3), 833-844, 1999 | 306 | 1999 |
Measuring picomolar intracellular exchangeable zinc in PC-12 cells using a ratiometric fluorescence biosensor RA Bozym, RB Thompson, AK Stoddard, CA Fierke ACS chemical biology 1 (2), 103-111, 2006 | 293 | 2006 |
Concentrations of extracellular free zinc (pZn) e in the central nervous system during simple anesthetization, ischemia and reperfusion CJ Frederickson, LJ Giblin, A Krężel, DJ McAdoo, RN Muelle, Y Zeng, ... Experimental neurology 198 (2), 285-293, 2006 | 278 | 2006 |
Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and1H assignments of human carbonic anhydrase II RA Venters, BT Farmer II, CA Fierke, LD Spicer Journal of molecular biology 264 (5), 1101-1116, 1996 | 239 | 1996 |
Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA S Niranjanakumari, T Stams, SM Crary, DW Christianson, CA Fierke Proceedings of the National Academy of Sciences 95 (26), 15212-15217, 1998 | 238 | 1998 |
Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors, DP Dowling, SL Gantt, SG Gattis, CA Fierke, DW Christianson Biochemistry 47 (51), 13554-13563, 2008 | 236 | 2008 |
Biochemical characterization of the Yersinia YopT protease: Cleavage site and recognition elements in Rho GTPases F Shao, PO Vacratsis, Z Bao, KE Bowers, CA Fierke, JE Dixon Proceedings of the National Academy of Sciences 100 (3), 904-909, 2003 | 235 | 2003 |
Zinc hydrolases: the mechanisms of zinc-dependent deacetylases M Hernick, CA Fierke Archives of biochemistry and biophysics 433 (1), 71-84, 2005 | 233 | 2005 |
Protein component of Bacillus subtilis RNase P specifically enhances the affinity for precursor-tRNAAsp JC Kurz, S Niranjanakumari, CA Fierke Biochemistry 37 (8), 2393-2400, 1998 | 233 | 1998 |
Hydrogen bond network in the metal binding site of carbonic anhydrase enhances zinc affinity and catalytic efficiency LL Kiefer, SA Paterno, CA Fierke Journal of the american chemical society 117 (26), 6831-6837, 1995 | 228 | 1995 |
Ribonuclease P protein structure: evolutionary origins in the translational apparatus T Stams, S Niranjanakumari, CA Fierke, DW Christianson Science 280 (5364), 752-755, 1998 | 222 | 1998 |
Antibacterial Agents That Target Lipid A Biosynthesis in Gram-negative Bacteria: Inhibition of diverse UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylases by … JE Jackman, CA Fierke, LN Tumey, M Pirrung, T Uchiyama, SH Tahir, ... Journal of Biological Chemistry 275 (15), 11002-11009, 2000 | 217 | 2000 |
Evidence for a catalytic role of zinc in protein farnesyltransferase: Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate CC Huang, PJ Casey, CA Fierke Journal of Biological Chemistry 272 (1), 20-23, 1997 | 216 | 1997 |
Insights into enzyme function from studies on mutants of dihydrofolate reductase SJ Benkovic, CA Fierke, AM Naylor Science 239 (4844), 1105-1110, 1988 | 209 | 1988 |
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121. SK Nair, TL Calderone, DW Christianson, CA Fierke Journal of biological chemistry 266 (26), 17320-17325, 1991 | 202 | 1991 |
Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes S Xiao, F Scott, CA Fierke, DR Engelke Annual review of biochemistry 71 (1), 165-189, 2002 | 194 | 2002 |
A kinetic mechanism for cleavage of precursor tRNAAsp catalyzed by the RNA component of Bacillus subtilis ribonuclease P JA Beebe, CA Fierke Biochemistry 33 (34), 10294-10304, 1994 | 190 | 1994 |