Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes E Ferrannini, S Baldi, S Frascerra, B Astiarraga, T Heise, R Bizzotto, ... Diabetes 65 (5), 1190-1195, 2016 | 666 | 2016 |
A reference map of potential determinants for the human serum metabolome N Bar, T Korem, O Weissbrod, D Zeevi, D Rothschild, S Leviatan, ... Nature 588 (7836), 135-140, 2020 | 298 | 2020 |
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study A Wesolowska-Andersen, CA Brorsson, R Bizzotto, A Mari, A Tura, ... Cell Reports Medicine 3 (1), 100477, 2022 | 59 | 2022 |
Multinomial logistic estimation of Markov-chain models for modeling sleep architecture in primary insomnia patients R Bizzotto, S Zamuner, G De Nicolao, MO Karlsson, R Gomeni Journal of pharmacokinetics and pharmacodynamics 37 (2), 137-155, 2010 | 46 | 2010 |
Pharmacometrics Markup Language (PharmML): opening new perspectives for model exchange in drug development MJ Swat, S Moodie, SM Wimalaratne, NR Kristensen, M Lavielle, A Mari, ... CPT: pharmacometrics & systems pharmacology 4 (6), 316-319, 2015 | 41 | 2015 |
Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials AY Dawed, A Mari, A Brown, TJ McDonald, L Li, S Wang, MG Hong, ... The Lancet Diabetes & Endocrinology 11 (1), 33-41, 2023 | 39 | 2023 |
Mixed meal ingestion diminishes glucose excursion in comparison with glucose ingestion via several adaptive mechanisms in people with and without type 2 diabetes W Alsalim, A Tura, G Pacini, B Omar, R Bizzotto, A Mari, B Ahrén Diabetes, Obesity and Metabolism 18 (1), 24-33, 2016 | 39 | 2016 |
Incretin and islet hormone responses to meals of increasing size in healthy subjects W Alsalim, B Omar, G Pacini, R Bizzotto, A Mari, B Ahrén The Journal of Clinical Endocrinology & Metabolism 100 (2), 561-568, 2015 | 38 | 2015 |
Mathematical modeling for the physiological and clinical investigation of glucose homeostasis and diabetes A Mari, A Tura, E Grespan, R Bizzotto Frontiers in Physiology, 1548, 2020 | 36 | 2020 |
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models RL Allesøe, AT Lundgaard, RH Medina, A Aguayo-Orozco, J Johansen, ... Nature Biotechnology 41 (3), 399-408, 2023 | 34 | 2023 |
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study E Karimian Azari, KR Smith, F Yi, TF Osborne, R Bizzotto, A Mari, ... The American journal of clinical nutrition 105 (4), 1001-1009, 2017 | 31 | 2017 |
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration HR Wilman, CA Parisinos, N Atabaki-Pasdar, M Kelly, EL Thomas, ... Journal of hepatology 71 (3), 594-602, 2019 | 29 | 2019 |
Effect of single‐dose DPP‐4 inhibitor sitagliptin on β‐cell function and incretin hormone secretion after meal ingestion in healthy volunteers and drug‐naïve, well‐controlled … W Alsalim, O Göransson, RD Carr, R Bizzotto, A Tura, G Pacini, A Mari, ... Diabetes, Obesity and Metabolism 20 (4), 1080-1085, 2018 | 22 | 2018 |
New Insights on the Interactions Between Insulin Clearance and the Main Glucose Homeostasis Mechanisms R Bizzotto, D Tricò, A Natali, A Gastaldelli, E Muscelli, RA De Fronzo, ... Diabetes Care 44 (9), 2115-2123, 2021 | 18 | 2021 |
Processes underlying glycemic deterioration in type 2 diabetes: An IMI DIRECT study R Bizzotto, C Jennison, A Jones, A Kurbasic, G Kennedy, JD Bell, ... Diabetes Care 44 (2), 511-518, 2021 | 18 | 2021 |
Multinomial logistic functions in Markov chain models of sleep architecture: internal and external validation and covariate analysis R Bizzotto, S Zamuner, E Mezzalana, G De Nicolao, R Gomeni, ... The AAPS journal 13, 445-463, 2011 | 15 | 2011 |
GLP-1 response to sequential mixed meals: influence of insulin resistance E Rebelos, B Astiarraga, R Bizzotto, A Mari, ML Manca, A Gonzalez, ... Clinical Science 131 (24), 2901-2910, 2017 | 13 | 2017 |
Adaptation of β-Cell and Endothelial Function to Carbohydrate Loading: Influence of Insulin Resistance BE Hurwitz, N Schneiderman, JB Marks, AJ Mendez, A Gonzalez, ... Diabetes 64 (7), 2550-2559, 2015 | 13 | 2015 |
Increased insulin clearance in mice with double deletion of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors A Tura, R Bizzotto, Y Yamada, Y Seino, G Pacini, B Ahrén American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018 | 12 | 2018 |
Model Description Language (MDL): A Standard for Modeling and Simulation MK Smith, SL Moodie, R Bizzotto, E Blaudez, E Borella, L Carrara, ... CPT: Pharmacometrics & Systems Pharmacology 6 (10), 647-650, 2017 | 12 | 2017 |