Advances in oligonucleotide drug delivery TC Roberts, R Langer, MJA Wood Nature reviews Drug discovery 19 (10), 673-694, 2020 | 1315 | 2020 |
The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease TC Roberts, KV Morris, MJA Wood Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 206 | 2014 |
The microRNA biology of the mammalian nucleus TC Roberts Molecular Therapy-Nucleic Acids 3, 2014 | 205 | 2014 |
The viral protein corona directs viral pathogenesis and amyloid aggregation K Ezzat, M Pernemalm, S Pålsson, TC Roberts, P Järver, A Dondalska, ... Nature communications 10 (1), 2331, 2019 | 187 | 2019 |
Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs TC Roberts, KV Morris, MS Weinberg Epigenetics 9 (1), 13-20, 2014 | 155* | 2014 |
Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy TC Roberts, KEM Blomberg, G McClorey, SEL Andaloussi, C Godfrey, ... Molecular Therapy-Nucleic Acids 1, 2012 | 153 | 2012 |
Assessment of RT-qPCR normalization strategies for accurate quantification of extracellular microRNAs in murine serum TC Roberts, AML Coenen-Stass, MJA Wood PloS one 9 (2), e89237, 2014 | 149 | 2014 |
Quantification of nascent transcription by bromouridine immunocapture nuclear run-on RT-qPCR TC Roberts, JR Hart, MU Kaikkonen, MS Weinberg, PK Vogt, KV Morris Nature protocols 10 (8), 1198-1211, 2015 | 104 | 2015 |
Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover TC Roberts, C Godfrey, G McClorey, P Vader, D Briggs, C Gardiner, ... Nucleic acids research 41 (20), 9500-9513, 2013 | 101 | 2013 |
MYC regulates the non-coding transcriptome JR Hart, TC Roberts, MS Weinberg, KV Morris, PK Vogt Oncotarget 5 (24), 12543, 2014 | 91 | 2014 |
Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer J Voutila, V Reebye, TC Roberts, P Protopapa, P Andrikakou, DC Blakey, ... Molecular Therapy 25 (12), 2705-2714, 2017 | 89 | 2017 |
Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model B Bestas, PMD Moreno, KEM Blomberg, DK Mohammad, AF Saleh, ... The Journal of clinical investigation 124 (9), 4067-4081, 2014 | 75 | 2014 |
Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress TA Turunen, TC Roberts, P Laitinen, MA Väänänen, P Korhonen, T Malm, ... Scientific reports 9 (1), 10332, 2019 | 68 | 2019 |
Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies J Rouillon, J Poupiot, A Zocevic, F Amor, T Léger, C Garcia, JM Camadro, ... Human molecular genetics 24 (17), 4916-4932, 2015 | 68 | 2015 |
Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics AML Coenen-Stass, G McClorey, R Manzano, CA Betts, A Blain, AF Saleh, ... Scientific reports 5 (1), 17014, 2015 | 67 | 2015 |
Therapeutic targeting of non-coding RNAs TC Roberts, MJA Wood Essays in biochemistry 54, 127-145, 2013 | 67 | 2013 |
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics AML Coenen-Stass, MJ Pauwels, B Hanson, C Martin Perez, ... RNA biology 16 (5), 696-706, 2019 | 66 | 2019 |
Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice CA Betts, AF Saleh, CA Carr, SM Hammond, AML Coenen-Stass, ... Scientific reports 5 (1), 8986, 2015 | 63 | 2015 |
Biomarker potential of extracellular miRNAs in Duchenne muscular dystrophy AML Coenen-Stass, MJA Wood, TC Roberts Trends in molecular medicine 23 (11), 989-1001, 2017 | 62 | 2017 |
GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain GH Dar, CC Mendes, WL Kuan, AA Speciale, M Conceição, A Görgens, ... Nature communications 12 (1), 6666, 2021 | 61 | 2021 |