| Antibiotic discovery in the twenty-first century: current trends and future perspectives S Donadio, S Maffioli, P Monciardini, M Sosio, D Jabes The Journal of antibiotics 63 (8), 423-430, 2010 | 370 | 2010 |
| Discovering new bioactive molecules from microbial sources P Monciardini, M Iorio, S Maffioli, M Sosio, S Donadio Microbial biotechnology 7 (3), 209-220, 2014 | 201 | 2014 |
| Antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase: pseudouridimycin SI Maffioli, Z Yu, D Degen, T Carzaniga, G Del Gatto, S Serina, ... Cell 169 (7), 1240 - 1248, 2017 | 147 | 2017 |
| Mild and Reversible Dehydration of Primary Amides with PdCl2 in Aqueous Acetonitrile SI Maffioli, E Marzorati, A Marazzi Organic Letters 7 (23), 5237-5239, 2005 | 116 | 2005 |
| A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity M Iorio, O Sasso, SI Maffioli, R Bertorelli, P Monciardini, M Sosio, ... ACS chemical biology 9 (2), 398-404, 2014 | 107 | 2014 |
| The lantibiotic NAI-107 binds to bactoprenol-bound cell wall precursors and impairs membrane functions D Münch, A Müller, T Schneider, B Kohl, M Wenzel, JE Bandow, S Maffioli, ... Journal of Biological Chemistry 289 (17), 12063-12076, 2014 | 95 | 2014 |
| Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis MA Ortega, DP Cogan, S Mukherjee, N Garg, B Li, GN Thibodeaux, ... ACS chemical biology 12 (2), 548-557, 2017 | 85 | 2017 |
| GE23077 binds to the RNA polymerase ‘i’and ‘i+ 1’sites and prevents the binding of initiating nucleotides Y Zhang, D Degen, MX Ho, E Sineva, KY Ebright, YW Ebright, V Mekler, ... Elife 3, e02450, 2014 | 79 | 2014 |
| Bacterial RNA polymerase inhibitors: an organized overview of their structure, derivatives, biological activity and current clinical development status R Mariani, SI Maffioli Current medicinal chemistry 16 (4), 430-454, 2009 | 78 | 2009 |
| Brominated variant of the lantibiotic NAI-107 with enhanced antibacterial potency JCS Cruz, M Iorio, P Monciardini, M Simone, C Brunati, E Gaspari, ... Journal of natural products 78 (11), 2642-2647, 2015 | 54 | 2015 |
| Analysis of the pseudouridimycin biosynthetic pathway provides insights into the formation of C-nucleoside antibiotics M Sosio, E Gaspari, M Iorio, S Pessina, MH Medema, A Bernasconi, ... Cell chemical biology 25 (5), 540-549. e4, 2018 | 52 | 2018 |
| Capturing linear intermediates and C-terminal variants during maturation of the thiopeptide GE2270 A Tocchetti, S Maffioli, M Iorio, S Alt, E Mazzei, C Brunati, M Sosio, ... Chemistry & biology 20 (8), 1067-1077, 2013 | 51 | 2013 |
| Insights into an unusual nonribosomal peptide synthetase biosynthesis: identification and characterization of the GE81112 biosynthetic gene cluster TM Binz, SI Maffioli, M Sosio, S Donadio, R Müller Journal of Biological Chemistry 285 (43), 32710-32719, 2010 | 47 | 2010 |
| The genus Actinoallomurus and some of its metabolites R Pozzi, M Simone, C Mazzetti, S Maffioli, P Monciardini, L Cavaletti, ... The Journal of antibiotics 64 (1), 133-139, 2011 | 46 | 2011 |
| A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters MM Zdouc, MM Alanjary, GS Zarazúa, SI Maffioli, M Crüsemann, ... Cell Chemical Biology 28 (5), 733-739. e4, 2021 | 45 | 2021 |
| Characterization of the congeners in the lantibiotic NAI-107 complex SI Maffioli, M Iorio, M Sosio, P Monciardini, E Gaspari, S Donadio Journal of natural products 77 (1), 79-84, 2014 | 42 | 2014 |
| Sources of novel antibiotics—aside the common roads S Donadio, S Maffioli, P Monciardini, M Sosio, D Jabes Applied microbiology and biotechnology 88 (6), 1261-1267, 2010 | 40 | 2010 |
| Synthesis and preliminary biological characterization of new semisynthetic derivatives of ramoplanin R Ciabatti, SI Maffioli, G Panzone, A Canavesi, E Michelucci, PS Tiseni, ... Journal of medicinal chemistry 50 (13), 3077-3085, 2007 | 37 | 2007 |
| Characterization of madurastatin C1, a novel siderophore from Actinomadura sp. E Mazzei, M Iorio, SI Maffioli, M Sosio, S Donadio The Journal of Antibiotics 65 (5), 267-269, 2012 | 36 | 2012 |
| Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells C Brunati, TT Thomsen, E Gaspari, S Maffioli, M Sosio, D Jabes, ... Journal of Antimicrobial Chemotherapy 73 (2), 414-424, 2018 | 35 | 2018 |
