Sulfadiazine Exerts Potential Anticancer Effect in HepG2 and MCF7 Cells by Inhibiting TNFα, IL1b, COX-1, COX-2, 5-LOX Gene Expression: Evidence from In Vitro and Computational … M Gomaa, W Gad, D Hussein, FH Pottoo, N Tawfeeq, M Alturki, D Alfahad, ... Pharmaceuticals 17 (2), 189, 2024 | 6 | 2024 |
Polyisoprenylated Cysteinyl Amide Inhibitors: A Novel Approach to Controlling Cancers with Hyperactive Growth Signaling NS Lamango, AT Nkembo, E Ntantie, N Tawfeeq Current Medicinal Chemistry 28 (18), 3476-3489, 2021 | 5 | 2021 |
Synthetic Optimization and MAPK Pathway Activation Anticancer Mechanism of Polyisoprenylated Cysteinyl Amide Inhibitors N Tawfeeq, Y Jin, NS Lamango Cancers 13 (22), 5757, 2021 | 4 | 2021 |
Synthetic Optimization and MAPK Pathway Activation Anticancer Mechanism of Polyisoprenylated Cysteinyl Amide Inhibitors. Cancers (Basel). 2021; 13: 5757 N Tawfeeq, Y Jin, NS Lamango Epub 2021/11/28. https://doi. org/10.3390/cancers13225757 PMID: 34830912, 2021 | 3 | 2021 |
Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines N Tawfeeq, JMS Lazarte, Y Jin, MD Gregory, NS Lamango Oncotarget 14, 243, 2023 | 2 | 2023 |
Discovery of Non-Peptide GLP-1 Positive Allosteric Modulators from Natural Products: Virtual Screening, Molecular Dynamics, ADMET Profiling, Repurposing, and Chemical Scaffolds … MS Gomaa, MS Alturki, N Tawfeeq, DA Hussein, FH Pottoo, AH Al Khzem, ... Pharmaceutics 16 (12), 1607, 2024 | 1 | 2024 |
PCAI-induced phosphorylation of MAP kinase pathway enzymes is associated with cell death of black American lung adenocarcinoma cell line NCI-H23 MD Gregory, N Tawfeeq, JM Lazarte, Y Jin, P Puente, N Belony, ... Cancer Research 82 (12_Supplement), 2680-2680, 2022 | 1 | 2022 |
Drug Repurposing for Cancer Treatment: A Comprehensive Review AH Al Khzem, MS Gomaa, MS Alturki, N Tawfeeq, M Sarafroz, ... International Journal of Molecular Sciences 25 (22), 12441, 2024 | | 2024 |
Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces … MD Gregory, K Ofosu-Asante, JMS Lazarte, PE Puente, N Tawfeeq, ... PloS one 19 (10), e0312563, 2024 | | 2024 |
Targeting Shikimate Kinase in Acinetobacter baumannii: Gallic Acid as a Potent Inhibitory Metabolite from FDA-Approved Drug Screening MS Alturki, AH Al Khzem, M Gomaa, N Tawfeeq, MH Alhamadah, ... | | 2024 |
Treatment of a Black American lung cancer cell line harboring KRAS mutations with polyisoprenylated cysteinyl amide inhibitors reveals effects on the MAP kinase signaling … MD Gregory, PE Puente, NL Belony, JMS Lazarte, N Tawfeeq, Y Huang, ... CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 32 (1), 237-238, 2023 | | 2023 |
Abstract C022: Treatment of a Black American lung cancer cell line harboring KRAS mutations with polyisoprenylated cysteinyl amide inhibitors reveals effects on the MAP kinase … MD Gregory, PE Puente, NL Belony, JMS Lazarte, N Tawfeeq, Y Huang, ... Cancer Epidemiology, Biomarkers & Prevention 32 (1_Supplement), C022-C022, 2023 | | 2023 |
Activation of MAP kinase pathway in breast cancer cell lines by polyisoprenylated cysteinyl amide inhibitors (PCAIs) causes cell death JM Lazarte, N Tawfeeq, Y Jin, N Lamango Cancer Research 82 (12_Supplement), 2683-2683, 2022 | | 2022 |
MAPK signaling pathway disruption explains the anticancer mechanism for polyisoprenylated cysteinyl amide inhibitors (PCAIs) N Tawfeeq, Y Jin, N Lamango Cancer Research 81 (13_Supplement), 2273-2273, 2021 | | 2021 |
Targeting KRAS Mutant Cancers with Polyisoprenylated Cysteinyl Amide Inhibitors N Tawfeeq Florida Agricultural and Mechanical University, 2021 | | 2021 |
Synthetic optimization of polyisoprenylated cysteinyl amide inhibitors to target cancers with hyperactive G-proteins N Tawfeeq, Y Jin, NS Lamango Cancer Research 80 (16_Supplement), 2591-2591, 2020 | | 2020 |
Disrupting the protein signaling activity of MAPK pathway as target for metastatic colorectal cancer therapy AT Nkembo, NS Lamango, Y Jin, N Tawfeeq, J Mensah-Mamfo The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Synthesis and Studies of N, N‐(Dimethylamino) Methylene Prodrugs of Gemcitabine, Ara‐A and Ara‐G N Tawfeeq, S Kerr The FASEB Journal 30, 937.11-937.11, 2016 | | 2016 |
Synthesis and Physicochemical Studies of N, N-(dimethylamino) Methylene Prodrugs of Nucleoside Analogs N Tawfeeq Massachusetts College of Pharmacy and Health Sciences, 2015 | | 2015 |