Halogen atoms in the modern medicinal chemistry: hints for the drug design MZ Hernandes, SMT Cavalcanti, DRM Moreira, WF de Azevedo Junior, ... Current drug targets 11 (3), 303-314, 2010 | 659 | 2010 |
Rotational features of carbon-nitrogen bonds in axially chiral o-tert-butyl anilides and related molecules. Potential substrates for the ‘prochiral auxiliary’approach to … DP Curran, GR Hale, SJ Geib, A Balog, QB Cass, ALG Degani, ... Tetrahedron: Asymmetry 8 (23), 3955-3975, 1997 | 148 | 1997 |
Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi ACL Leite, RS de Lima, DRM Moreira, MVO Cardoso, ACG de Brito, ... Bioorganic & medicinal chemistry 14 (11), 3749-3757, 2006 | 143 | 2006 |
2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ... European Journal of Medicinal Chemistry 86, 48-59, 2014 | 120 | 2014 |
Synthesis and anti-inflammatory activity of new arylidene-thiazolidine-2, 4-diones as PPARγ ligands CD Barros, AA Amato, TB de Oliveira, KBR Iannini, AL da Silva, ... Bioorganic & medicinal chemistry 18 (11), 3805-3811, 2010 | 110 | 2010 |
Quercetin as an inhibitor of snake venom secretory phospholipase A2 CA Cotrim, SCB de Oliveira, EBS Diz Filho, FV Fonseca, L Baldissera Jr, ... Chemico-Biological Interactions 189 (1-2), 9-16, 2011 | 89 | 2011 |
Selective and mild oxidation of sulfides to sulfoxides by oxodiperoxo molybdenum complexes adsorbed onto silica gel F Batigalhia, M Zaldini-Hernandes, AG Ferreira, I Malvestiti, QB Cass Tetrahedron 57 (48), 9669-9676, 2001 | 85 | 2001 |
Synthesis, Cruzain Docking, and in vitro Studies of Aryl‐4‐Oxothiazolylhydrazones Against Trypanosoma cruzi ACL Leite, DR de M. Moreira, MV de O. Cardoso, MZ Hernandes, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (9), 1339-1345, 2007 | 82 | 2007 |
Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities LFC da Costa Leite, RHV Mourão, MCA de Lima, SL Galdino, ... European journal of medicinal chemistry 42 (10), 1263-1271, 2007 | 79 | 2007 |
The use of solid dispersion systems in hydrophilic carriers to increase benznidazole solubility ÁAN Lima, JL Soares‐Sobrinho, JL Silva, RAC Corrêa‐Júnior, MAM Lyra, ... Journal of pharmaceutical sciences 100 (6), 2443-2451, 2011 | 78 | 2011 |
The encapsulation of β-lapachone in 2-hydroxypropyl-β-cyclodextrin inclusion complex into liposomes: a physicochemical evaluation and molecular modeling approach IMF Cavalcanti, EAM Mendonça, MCB Lira, SB Honrato, CA Camara, ... European journal of pharmaceutical sciences 44 (3), 332-340, 2011 | 76 | 2011 |
Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice DRM Moreira, SPM Costa, MZ Hernandes, MM Rabello, ... Journal of Medicinal Chemistry 55 (24), 10918-10936, 2012 | 74 | 2012 |
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents MZ Hernandes, MM Rabello, ACL Leite, MVO Cardoso, DRM Moreira, ... Bioorganic & Medicinal Chemistry 18 (22), 7826-7835, 2010 | 69 | 2010 |
New 1, 3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi PAT de Moraes Gomes, M de Oliveira Barbosa, EF Santiago, ... European Journal of Medicinal Chemistry 121, 387-398, 2016 | 61 | 2016 |
Structural Design, Synthesis and Structure–Activity Relationships of Thiazolidinones with Enhanced Anti‐Trypanosoma cruzi Activity DRM Moreira, AC Lima Leite, MVO Cardoso, RM Srivastava, ... ChemMedChem 9 (1), 177-188, 2014 | 55 | 2014 |
A theoretical study of red-shifting and blue-shifting hydrogen bonds occurring between imidazolidine derivatives and PEG/PVP polymers BG Oliveira, MCA Lima, IR Pitta, SL Galdino, MZ Hernandes Journal of molecular modeling 16, 119-127, 2010 | 51 | 2010 |
Discovery of phthalimides as immunomodulatory and antitumor drug prototypes C Pessoa, PMP Ferreira, LVC Lotufo, MO de Moraes, SMT Cavalcanti, ... ChemMedChem 5 (4), 523-528, 2010 | 48 | 2010 |
Thiosemicarbazones as Aedes aegypti larvicidal JBP da Silva, DM do AF Navarro, AG da Silva, GKN Santos, KA Dutra, ... European journal of medicinal chemistry 100, 162-175, 2015 | 45 | 2015 |
Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities MV de Oliveira Cardoso, DRM Moreira, GB Oliveira Filho, SMT Cavalcanti, ... European Journal of Medicinal Chemistry 96, 491-503, 2015 | 44 | 2015 |
Interaction of morphine with a new α2-adrenoceptor agonist in mice RT Sudo, JA Calasans-Maia, SL Galdino, MCA Lima, G Zapata-Sudo, ... The Journal of Pain 11 (1), 71-78, 2010 | 41 | 2010 |