Caudo‐rostral brain spreading of α‐synuclein through vagal connections A Ulusoy, R Rusconi, BI Pérez‐Revuelta, RE Musgrove, M Helwig, ... EMBO molecular medicine 5 (7), 1119-1127, 2013 | 293 | 2013 |
α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease I Lastres-Becker, A Ulusoy, NG Innamorato, G Sahin, A Rábano, D Kirik, ... Human molecular genetics 21 (14), 3173-3192, 2012 | 280 | 2012 |
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson’s disease M Decressac, A Ulusoy, B Mattsson, B Georgievska, M Romero-Ramos, ... Brain 134 (8), 2302-2311, 2011 | 221 | 2011 |
Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections A Ulusoy, RJ Phillips, M Helwig, M Klinkenberg, TL Powley, DA Di Monte Acta neuropathologica 133, 381-393, 2017 | 185 | 2017 |
Oxidative stress in vagal neurons promotes parkinsonian pathology and intercellular α-synuclein transfer RE Musgrove, M Helwig, EJ Bae, H Aboutalebi, SJ Lee, A Ulusoy, ... The Journal of clinical investigation 129 (9), 3738-3753, 2019 | 166 | 2019 |
Viral vector-mediated overexpression of α-synuclein as a progressive model of Parkinson’s disease A Ulusoy, M Decressac, D Kirik, A Björklund Progress in brain research 184, 89-111, 2010 | 155 | 2010 |
LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation EJ Bae, DK Kim, C Kim, M Mante, A Adame, E Rockenstein, A Ulusoy, ... Nature communications 9 (1), 3465, 2018 | 146 | 2018 |
Co‐expression of C‐terminal truncated alpha‐synuclein enhances full‐length alpha‐synuclein‐induced pathology A Ulusoy, F Febbraro, PH Jensen, D Kirik, M Romero‐Ramos European Journal of Neuroscience 32 (3), 409-422, 2010 | 128 | 2010 |
Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease C Milanese, S Cerri, A Ulusoy, SV Gornati, A Plat, S Gabriels, F Blandini, ... Cell death & disease 9 (8), 818, 2018 | 112 | 2018 |
Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice M Helwig, M Klinkenberg, R Rusconi, RE Musgrove, NK Majbour, ... Brain 139 (3), 856-870, 2016 | 109 | 2016 |
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury A Ulusoy, RE Musgrove, R Rusconi, M Klinkenberg, M Helwig, ... Acta neuropathologica communications 3, 1-13, 2015 | 105 | 2015 |
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo TG McWilliams, E Barini, R Pohjolan-Pirhonen, SP Brooks, F Singh, ... Royal Society Open Biology 8 (11), 180108, 2018 | 102 | 2018 |
Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons A Ulusoy, G Sahin, T Björklund, P Aebischer, D Kirik Molecular Therapy 17 (9), 1574-1584, 2009 | 95 | 2009 |
In vivo models of alpha-synuclein transmission and propagation A Recasens, A Ulusoy, PJ Kahle, DA Di Monte, B Dehay Cell and tissue research 373, 183-193, 2018 | 71 | 2018 |
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons A Ulusoy, T Björklund, K Buck, D Kirik Neurobiology of disease 47 (3), 367-377, 2012 | 68 | 2012 |
Synapsin condensates recruit alpha-synuclein C Hoffmann, R Sansevrino, G Morabito, C Logan, RM Vabulas, A Ulusoy, ... Journal of molecular biology 433 (12), 166961, 2021 | 65 | 2021 |
Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA–induced dyskinesia in rats A Ulusoy, G Sahin, D Kirik Proceedings of the National Academy of Sciences 107 (29), 13159-13164, 2010 | 63 | 2010 |
α-Synuclein elevation in human neurodegenerative diseases: experimental, pathogenetic, and therapeutic implications A Ulusoy, DA Di Monte Molecular neurobiology 47, 484-494, 2013 | 62 | 2013 |
In vivo gene delivery for development of mammalian models for Parkinson's disease A Ulusoy, T Bjorklund, S Hermening, D Kirik Experimental neurology 209 (1), 89-100, 2008 | 52 | 2008 |
Animal models of brain-first and body-first Parkinson's disease N Van Den Berge, A Ulusoy Neurobiology of disease 163, 105599, 2022 | 50 | 2022 |