| Understanding and overcoming trade-offs between antibody affinity, specificity, stability and solubility LA Rabia, AA Desai, HS Jhajj, PM Tessier Biochemical engineering journal 137, 365-374, 2018 | 134 | 2018 |
| Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ... Nature communications 13 (1), 3788, 2022 | 76 | 2022 |
| Physicochemical rules for identifying monoclonal antibodies with drug-like specificity Y Zhang, L Wu, P Gupta, AA Desai, MD Smith, LA Rabia, SD Ludwig, ... Molecular pharmaceutics 17 (7), 2555-2569, 2020 | 43 | 2020 |
| Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis JM Zupancic, AA Desai, JS Schardt, G Pornnoppadol, EK Makowski, ... Cell Chemical Biology 28 (9), 1379-1388. e7, 2021 | 32 | 2021 |
| Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants JM Zupancic, JS Schardt, AA Desai, EK Makowski, MD Smith, ... Advanced Therapeutics, 2100099, 2021 | 32 | 2021 |
| Nature-inspired design and evolution of anti-amyloid antibodies MC Julian, LA Rabia, AA Desai, A Arsiwala, JE Gerson, HL Paulson, ... Journal of Biological Chemistry 294 (21), 8438-8451, 2019 | 30 | 2019 |
| Highly sensitive detection of antibody nonspecific interactions using flow cytometry EK Makowski, L Wu, AA Desai, PM Tessier MAbs 13 (1), 1951426, 2021 | 25 | 2021 |
| Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity AA Desai, MD Smith, Y Zhang, EK Makowski, JE Gerson, E Ionescu, ... Journal of Biological Chemistry 296, 2021 | 23 | 2021 |
| Reduction of therapeutic antibody self-association using yeast-display selections and machine learning EK Makowski, H Chen, M Lambert, EM Bennett, NS Eschmann, Y Zhang, ... MAbs 14 (1), 2146629, 2022 | 13 | 2022 |
| Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening JS Schardt, G Pornnoppadol, AA Desai, KS Park, JM Zupancic, ... Scientific Reports 11 (1), 20738, 2021 | 12 | 2021 |
| Sensitive detection of glucagon aggregation using amyloid fibril‐specific antibodies SD Stimple, S Kalyoncu, AA Desai, JE Mogensen, LT Spang, DJ Asgreen, ... Biotechnology and Bioengineering 116 (8), 1868-1877, 2019 | 8 | 2019 |
| Isolating anti-amyloid antibodies from yeast-displayed libraries AA Desai, JM Zupancic, MD Smith, PM Tessier Yeast Surface Display, 471-490, 2022 | 4 | 2022 |
| Facile isolation of high-affinity nanobodies from synthetic libraries using CDR-swapping mutagenesis JM Zupancic, AA Desai, PM Tessier STAR protocols 3 (1), 101101, 2022 | 4 | 2022 |
| Rapid and Quantitative In Vitro Evaluation of SARS-CoV-2 Neutralizing Antibodies and Nanobodies W Wu, X Tan, J Zupancic, JS Schardt, AA Desai, MD Smith, J Zhang, L Xie, ... Analytical chemistry 94 (10), 4504-4512, 2022 | 4 | 2022 |
| A hybridoma-derived monoclonal antibody with high homology to the aberrant myeloma light chain G Pornnoppadol, B Zhang, AA Desai, A Berardi, HA Remmer, PM Tessier, ... Plos one 16 (10), e0252558, 2021 | 4 | 2021 |
| Directed evolution of conformation‐specific antibodies for sensitive detection of polypeptide aggregates in therapeutic drug formulations W Lou, SD Stimple, AA Desai, EK Makowski, S Kalyoncu, JE Mogensen, ... Biotechnology and Bioengineering 118 (2), 797-808, 2021 | 3 | 2021 |
| Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils AA Desai, JM Zupancic, H Trzeciakiewicz, JE Gerson, KN DuBois, ... bioRxiv, 2023.07. 04.547698, 2023 | 2 | 2023 |
| Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies Y Han, AA Desai, JM Zupancic, MD Smith, PM Tessier, BT Ruotolo Protein Science 33 (6), e5008, 2024 | | 2024 |
| Facile generation of biepitopic antibodies with intrinsic agonism for activating tumor necrosis factor receptors HS Jhajj, JS Schardt, N Khalasawi, EL Yao, TS Lwo, NY Kwon, ... Cell Chemical Biology 31 (5), 944-954. e5, 2024 | | 2024 |
| In vivo Auto-tuning of Antibody-Drug Conjugate Delivery for Effective Immunotherapy using High-Avidity, Low-Affinity Antibodies A Kopp, S Dong, H Kwon, T Wang, AA Desai, JJ Linderman, P Tessier, ... bioRxiv, 2024 | | 2024 |
