关注
Philipp Wortmann
Philipp Wortmann
AstraZeneca Computational Pathology
在 tum.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
A primer to scaffolded DNA origami
CE Castro, F Kilchherr, DN Kim, EL Shiao, T Wauer, P Wortmann, ...
Nature methods 8 (3), 221-229, 2011
11152011
Multidomain structure and correlated dynamics determined by self-consistent FRET networks
B Hellenkamp, P Wortmann, F Kandzia, M Zacharias, T Hugel
Nature methods 14 (2), 174-180, 2017
1412017
Design and preclinical evaluation of a novel B7-H4–directed antibody–drug conjugate, AZD8205, alone and in combination with the PARP1-selective inhibitor AZD5305
K Kinneer, P Wortmann, ZA Cooper, NJ Dickinson, L Masterson, ...
Clinical Cancer Research 29 (6), 1086-1101, 2023
322023
Cooperative nucleotide binding in Hsp90 and its regulation by Aha1
P Wortmann, M Götz, T Hugel
Biophysical journal 113 (8), 1711-1718, 2017
302017
A multicolor single-molecule FRET approach to study protein dynamics and interactions simultaneously
M Götz, P Wortmann, S Schmid, T Hugel
Methods in enzymology 581, 487-516, 2016
302016
Using three-color single-molecule FRET to study the correlation of protein interactions
M Götz, P Wortmann, S Schmid, T Hugel
JoVE (Journal of Visualized Experiments), e56896, 2018
112018
Stain isolation-based guidance for improved stain translation
N Brieu, FJ Segerer, A Kapil, P Wortmann, G Schmidt
arXiv preprint arXiv:2207.00431, 2022
32022
Auxiliary CycleGAN-guidance for Task-Aware Domain Translation from Duplex to Monoplex IHC Images
N Brieu, N Triltsch, P Wortmann, D Winter, S Saran, M Rebelatto, ...
arXiv preprint arXiv:2403.07389, 2024
22024
Cooperative nucleotide binding in Hsp90 and the underlying mechanisms
P Wortmann, M Goötz, T Hugel
bioRxiv, 113191, 2017
22017
339 Quantitative assessment of CAR-T cell therapy targets using computational pathology
N Harder, M Schick, P Sontakke, A Andoni, K DaCosta, R Nalbandian, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
12022
Discovery and first disclosure of AZD8205, a B7-H4-targeted antibody-drug conjugate utilizing a novel topoisomerase I linker-warhead
K Kinneer, NJ Dickinson, L Masterson, T Cailleau, I Hutchinson, ...
Cancer Research 82 (12_Supplement), 1765-1765, 2022
12022
Quantitative assessment of IHC using computational pathology allows superior patient selection for biomarker-informed patients
H Sade, A Kapil, P Wortmann, A Spitzmueller, N Triltsch, L Meinecke, ...
Cancer Research 82 (12_Supplement), 468-468, 2022
12022
Determination of structural ensembles and correlated dynamics of a multi-domain protein
B Hellenkamp, T Hugel, P Wortmann, F Kandzia, M Zacharias
12017
The dynamics of the Hsp90 machine: studied by single molecule FRET
P Wortmann
Technische Universität München, 2017
12017
A Scoring Method for an Anti-B7H4 Antibody-Drug Conjugate Therapy
G Schmidt, N Brieu, A Spitzmueller, A Kapil, T Tan, P Wortmann
US Patent App. 18/025,883, 2024
2024
Single-molecule FRET and tracking of transfected biomolecules: multi-dimensional protein dynamics in living cells
A Anandamurugan, A Eidloth, P Wortmann, L Schrangl, F Aprile-Garcia, ...
bioRxiv, 2023.09. 15.557875, 2023
2023
Abstract P6-04-16: ART: Automated Region segmentation of Tumor on HER2-stained breast cancer tissue
A Kapil, A Shumilov, P Wortmann, S Khelifa, J Chan, M Vandenberghe, ...
Cancer Research 83 (5_Supplement), P6-04-16-P6-04-16, 2023
2023
Development and implementation of image analysis-based Quantitative Continuous Score (QCS) for B7-H4 IHC to understand AZD8205 pharmacodynamics
P Wortmann, TH Tan, S Haneder, AE Storti, A Kapil, J Chesebrough, ...
Cancer Research 82 (12_Supplement), 452-452, 2022
2022
Protein Conformational Dynamics In Cellula and IN VIVO Using Live-Cell Single-Molecule Fret Hilo Microscopy
A Anandamurugan, P Wortmann, C Lan, AG Fernando, M Veil, L Schrangl, ...
Biophysical Journal 120 (3), 114a, 2021
2021
Combining the best of two worlds: Transfer of multiplex immunofluorescence images from non-small cell lung carcinoma patients into pseudo multiplex chromogenic …
L Rognoni, AH Sastre, L Bruetzel, P Wortmann, M Baehner, M Testori, ...
JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019
2019
系统目前无法执行此操作,请稍后再试。
文章 1–20