Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ... Molecular cell 68 (2), 414-430. e8, 2017 | 351 | 2017 |
Phosphorylated CtIP functions as a co-factor of the MRE11-RAD50-NBS1 endonuclease in DNA end resection R Anand, L Ranjha, E Cannavo, P Cejka Molecular cell 64 (5), 940-950, 2016 | 326 | 2016 |
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ... Cell reports 20 (8), 1921-1935, 2017 | 174 | 2017 |
The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions L Ranjha, R Anand, P Cejka Journal of Biological Chemistry 289 (9), 5674-5686, 2014 | 144 | 2014 |
Regulation of the MLH1–MLH3 endonuclease in meiosis E Cannavo, A Sanchez, R Anand, L Ranjha, J Hugener, C Adam, ... Nature 586 (7830), 618-622, 2020 | 99 | 2020 |
RECQL4 promotes DNA end resection in repair of DNA double-strand breaks H Lu, RA Shamanna, G Keijzers, R Anand, LJ Rasmussen, P Cejka, ... Cell reports 16 (1), 161-173, 2016 | 97 | 2016 |
NBS1 promotes the endonuclease activity of the MRE11‐RAD50 complex by sensing CtIP phosphorylation R Anand, A Jasrotia, D Bundschuh, SM Howard, L Ranjha, M Stucki, ... The EMBO journal 38 (7), e101005, 2019 | 78 | 2019 |
CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection I Ceppi, SM Howard, K Kasaciunaite, C Pinto, R Anand, R Seidel, P Cejka Proceedings of the National Academy of Sciences 117 (16), 8859-8869, 2020 | 63 | 2020 |
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins O Belan, C Barroso, A Kaczmarczyk, R Anand, S Federico, N O’Reilly, ... Molecular cell 81 (5), 1058-1073. e7, 2021 | 61 | 2021 |
MRE11-RAD50-NBS1 complex is sufficient to promote transcription by RNA polymerase II at double-strand breaks by melting DNA ends S Sharma, R Anand, X Zhang, S Francia, F Michelini, A Galbiati, ... Cell reports 34 (1), 2021 | 57 | 2021 |
The Mre11-Nbs1 interface is essential for viability and tumor suppression JH Kim, M Grosbart, R Anand, C Wyman, P Cejka, JHJ Petrini Cell reports 18 (2), 496-507, 2017 | 57 | 2017 |
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells O Belan, M Sebald, M Adamowicz, R Anand, A Vancevska, J Neves, ... Molecular cell 82 (24), 4664-4680. e9, 2022 | 48 | 2022 |
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 R Anand, E Buechelmaier, O Belan, M Newton, A Vancevska, ... Nature 601 (7892), 268-273, 2022 | 42 | 2022 |
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage JW Huang, A Acharya, A Taglialatela, TS Nambiar, R Cuella-Martin, ... Nature communications 11 (1), 2948, 2020 | 37 | 2020 |
Methods to study DNA end resection I: recombinant protein purification R Anand, C Pinto, P Cejka Methods in enzymology 600, 25-66, 2018 | 31 | 2018 |
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2 S Halder, A Sanchez, L Ranjha, G Reginato, I Ceppi, A Acharya, R Anand, ... Molecular Cell 82 (19), 3553-3565. e5, 2022 | 26 | 2022 |
Competing interaction partners modulate the activity of Sgs1 helicase during DNA end resection K Kasaciunaite, F Fettes, M Levikova, P Daldrop, R Anand, P Cejka, ... The EMBO journal 38 (13), e101516, 2019 | 23 | 2019 |
Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet J Varghese, JV James, R Anand, M Narayanasamy, G Rebekah, ... The Journal of nutritional biochemistry 84, 108441, 2020 | 20 | 2020 |
Methods to study DNA end resection II: biochemical reconstitution assays C Pinto, R Anand, P Cejka Methods in enzymology 600, 67-106, 2018 | 17 | 2018 |
The internal region of CtIP negatively regulates DNA end resection SM Howard, I Ceppi, R Anand, R Geiger, P Cejka Nucleic acids research 48 (10), 5485-5498, 2020 | 14 | 2020 |