Direct conversion of fibroblasts into functional astrocytes by defined transcription factors M Caiazzo, S Giannelli, P Valente, G Lignani, A Carissimo, A Sessa, ... Stem cell reports 4 (1), 25-36, 2015 | 243 | 2015 |
dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice G Colasante, G Lignani, S Brusco, C Di Berardino, J Carpenter, ... Molecular Therapy 28 (1), 235-253, 2020 | 183 | 2020 |
Rapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming G Colasante, G Lignani, A Rubio, L Medrihan, L Yekhlef, A Sessa, ... Cell stem cell 17 (6), 719-734, 2015 | 176 | 2015 |
Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons G Colasante, P Collombat, V Raimondi, D Bonanomi, C Ferrai, M Maira, ... Journal of Neuroscience 28 (42), 10674-10686, 2008 | 164 | 2008 |
Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired … E Colombo, P Collombat, G Colasante, M Bianchi, J Long, A Mansouri, ... Journal of Neuroscience 27 (17), 4786-4798, 2007 | 148 | 2007 |
Remote control of induced dopaminergic neurons in parkinsonian rats MT Dell’Anno, M Caiazzo, D Leo, E Dvoretskova, L Medrihan, ... The Journal of clinical investigation 124 (7), 3215-3229, 2014 | 132 | 2014 |
Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of … A Sessa, CA Mao, G Colasante, A Nini, WH Klein, V Broccoli Genes & development 24 (16), 1816-1826, 2010 | 121 | 2010 |
Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors I Theka, M Caiazzo, E Dvoretskova, D Leo, F Ungaro, S Curreli, F Managò, ... Stem cells translational medicine 2 (6), 473-479, 2013 | 103 | 2013 |
In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy G Colasante, Y Qiu, L Massimino, C Di Berardino, JH Cornford, ... Brain 143 (3), 891-905, 2020 | 92 | 2020 |
Mouse orthologue of ARX, a gene mutated in several X‐linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons E Colombo, R Galli, G Cossu, J Gécz, V Broccoli Developmental dynamics: an official publication of the American Association …, 2004 | 92 | 2004 |
Aristaless-related homeobox gene, the gene responsible for West syndrome and related disorders, is a Groucho/transducin-like enhancer of split dependent transcriptional repressor O McKenzie, I Ponte, M Mangelsdorf, M Finnis, G Colasante, ... Neuroscience 146 (1), 236-247, 2007 | 77 | 2007 |
GAS2 and GAS4, a Pair of Developmentally Regulated Genes Required for Spore Wall Assembly in Saccharomyces cerevisiae E Ragni, A Coluccio, E Rolli, JM Rodriguez-Pena, G Colasante, J Arroyo, ... Eukaryotic cell 6 (2), 302-316, 2007 | 66 | 2007 |
ARX Regulates Cortical Intermediate Progenitor Cell Expansion and Upper Layer Neuron Formation Through Repression of Cdkn1c G Colasante, JC Simonet, R Calogero, S Crispi, A Sessa, G Cho, ... Cerebral cortex 25 (2), 322-335, 2015 | 63 | 2015 |
Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity G Colasante, A Sessa, S Crispi, R Calogero, A Mansouri, P Collombat, ... Developmental biology 334 (1), 59-71, 2009 | 62 | 2009 |
The Tbr2 molecular network controls cortical neuronal differentiation through complementary genetic and epigenetic pathways A Sessa, E Ciabatti, D Drechsel, L Massimino, G Colasante, S Giannelli, ... Cerebral cortex 27 (6), 3378-3396, 2017 | 58 | 2017 |
Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons PG Mazzara, S Muggeo, M Luoni, L Massimino, M Zaghi, PTT Valverde, ... Nature Communications 11 (1), 4178, 2020 | 55 | 2020 |
Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome N Valassina, S Brusco, A Salamone, L Serra, M Luoni, S Giannelli, S Bido, ... Nature communications 13 (1), 161, 2022 | 45 | 2022 |
Reconstitution of the human nigro-striatal pathway on-a-chip reveals OPA1-dependent mitochondrial defects and loss of dopaminergic synapses A Iannielli, GS Ugolini, C Cordiglieri, S Bido, A Rubio, G Colasante, ... Cell reports 29 (13), 4646-4656. e4, 2019 | 43 | 2019 |
Direct neuronal reprogramming reveals unknown functions for known transcription factors G Colasante, A Rubio, L Massimino, V Broccoli Frontiers in Neuroscience 13, 283, 2019 | 24 | 2019 |
CRISPR/dCas9 as a therapeutic approach for neurodevelopmental disorders: innovations and limitations compared to traditional strategies R Ricci, G Colasante Developmental Neuroscience 43 (3-4), 253-261, 2021 | 19 | 2021 |