Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency MG Agadjanyan, K Zagorski, I Petrushina, H Davtyan, K Kazarian, ... Molecular neurodegeneration 12, 1-18, 2017 | 56 | 2017 |
Assembly of α-synuclein aggregates on phospholipid bilayers Z Lv, M Hashemi, S Banerjee, K Zagorski, JC Rochet, YL Lyubchenko Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (9), 802-812, 2019 | 49* | 2019 |
Alzheimer’s disease AdvaxCpG- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Aβ pathological … H Davtyan, K Zagorski, H Rajapaksha, A Hovakimyan, A Davtyan, ... Scientific reports 6 (1), 28912, 2016 | 47 | 2016 |
Supported lipid bilayers for atomic force microscopy studies Z Lv, S Banerjee, K Zagorski, YL Lyubchenko Nanoscale Imaging: Methods and Protocols, 129-143, 2018 | 40 | 2018 |
Cholesterol in membranes facilitates aggregation of amyloid β protein at physiologically relevant concentrations S Banerjee, M Hashemi, K Zagorski, YL Lyubchenko ACS Chemical Neuroscience 12 (3), 506-516, 2021 | 38 | 2021 |
Interaction of Aβ42 with membranes triggers the self-assembly into oligomers S Banerjee, M Hashemi, K Zagorski, YL Lyubchenko International journal of molecular sciences 21 (3), 1129, 2020 | 35 | 2020 |
Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials I Petrushina, A Hovakimyan, IS Harahap-Carrillo, H Davtyan, T Antonyan, ... Neurobiology of disease 139, 104823, 2020 | 32 | 2020 |
Immunogenicity of DNA-and recombinant protein-based Alzheimer disease epitope vaccines H Davtyan, A Bacon, I Petrushina, K Zagorski, DH Cribbs, A Ghochikyan, ... Human vaccines & immunotherapeutics 10 (5), 1248-1255, 2014 | 31 | 2014 |
MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice H Davtyan, WW Chen, K Zagorski, J Davis, I Petrushina, K Kazarian, ... Vaccine 35 (16), 2015-2024, 2017 | 28 | 2017 |
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice H Davtyan, A Hovakimyan, S Kiani Shabestari, T Antonyan, MA Coburn, ... Alzheimer's Research & Therapy 11, 1-13, 2019 | 24 | 2019 |
Molecular model for the surface-catalyzed protein self-assembly Y Pan, S Banerjee, K Zagorski, LS Shlyakhtenko, AB Kolomeisky, ... The Journal of Physical Chemistry B 124 (2), 366-372, 2019 | 20* | 2019 |
Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology A Joly-Amado, H Davtyan, K Serraneau, P Jules, A Zitnyar, E Pressman, ... Neurobiology of disease 134, 104636, 2020 | 19 | 2020 |
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: Therapeutic efficacy in PS19 mice A Hovakimyan, T Antonyan, SK Shabestari, O Svystun, G Chailyan, ... Scientific reports 9 (1), 15455, 2019 | 19 | 2019 |
MultiTEP platform–based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency H Davtyan, K Zagorski, I Petrushina, K Kazarian, NRS Goldberg, ... Neurobiology of aging 59, 156-170, 2017 | 15 | 2017 |
Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: Prelude for IND enabling studies C Kim, A Hovakimyan, K Zagorski, T Antonyan, I Petrushina, H Davtyan, ... npj Vaccines 7 (1), 1, 2022 | 13 | 2022 |
BTX AgilePulseTM system is an effective electroporation device for intramuscular and intradermal delivery of DNA vaccine H Davtyan, A Hovakimyan, K Zagorski, A Davtyan, I Petrushina, ... Current Gene Therapy 14 (3), 190-199, 2014 | 13 | 2014 |
Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates A Hovakimyan, K Zagorski, G Chailyan, T Antonyan, L Melikyan, ... npj Vaccines 7 (1), 117, 2022 | 10 | 2022 |
The enzymatic activity of APOBE3G multimers Y Pan, K Zagorski, LS Shlyakhtenko, YL Lyubchenko Scientific reports 8 (1), 17953, 2018 | 6 | 2018 |
Immunogenicity of multiTEP-platform-based recombinant protein vaccine, PV-1950R, targeting three B-cell antigenic determinants of pathological α-synuclein K Zagorski, G Chailyan, A Hovakimyan, T Antonyan, S Kiani Shabestari, ... International journal of molecular sciences 23 (11), 6080, 2022 | 5 | 2022 |
Modular nanoarray vaccine for SARS-CoV-2 K Zagorski, K Pandey, R Rajaiah, OA Olwenyi, AN Bade, A Acharya, ... Nanomedicine: Nanotechnology, Biology and Medicine 46, 102604, 2022 | 4 | 2022 |