Regulation of neuronal survival by the serine-threonine protein kinase Akt H Dudek, SR Datta, TF Franke, MJ Birnbaum, R Yao, GM Cooper, ... Science 275 (5300), 661-665, 1997 | 3091 | 1997 |
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ) H Cho, J Mu, JK Kim, JL Thorvaldsen, Q Chu, EB Crenshaw III, ... Science 292 (5522), 1728-1731, 2001 | 2353 | 2001 |
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus Y Minokoshi, T Alquier, N Furukawa, YB Kim, A Lee, B Xue, J Mu, ... Nature 428 (6982), 569-574, 2004 | 1999 | 2004 |
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint RG Jones, DR Plas, S Kubek, M Buzzai, J Mu, Y Xu, MJ Birnbaum, ... Molecular cell 18 (3), 283-293, 2005 | 1925 | 2005 |
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation AD Kohn, SA Summers, MJ Birnbaum, RA Roth Journal of Biological Chemistry 271 (49), 31372-31378, 1996 | 1680 | 1996 |
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance WL Holland, JT Brozinick, LP Wang, ED Hawkins, KM Sargent, Y Liu, ... Cell metabolism 5 (3), 167-179, 2007 | 1372 | 2007 |
Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice H Cho, JL Thorvaldsen, Q Chu, F Feng, MJ Birnbaum Journal of Biological Chemistry 276 (42), 38349-38352, 2001 | 1318 | 2001 |
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation H Zong, JM Ren, LH Young, M Pypaert, J Mu, MJ Birnbaum, GI Shulman Proceedings of the national academy of sciences 99 (25), 15983-15987, 2002 | 1236 | 2002 |
A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle J Mu, JT Brozinick, O Valladares, M Bucan, MJ Birnbaum Molecular cell 7 (5), 1085-1094, 2001 | 1151 | 2001 |
Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia ES Emamian, D Hall, MJ Birnbaum, M Karayiorgou, JA Gogos Nature genetics 36 (2), 131-137, 2004 | 1135 | 2004 |
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ... Cell 142 (2), 270-283, 2010 | 1107 | 2010 |
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP RA Miller, Q Chu, J Xie, M Foretz, B Viollet, MJ Birnbaum Nature 494 (7436), 256-260, 2013 | 1032 | 2013 |
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin WL Holland, RA Miller, ZV Wang, K Sun, BM Barth, HH Bui, KE Davis, ... Nature medicine 17 (1), 55-63, 2011 | 1005 | 2011 |
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury RR Russell, J Li, DL Coven, M Pypaert, C Zechner, M Palmeri, ... The Journal of clinical investigation 114 (4), 495-503, 2004 | 878 | 2004 |
Role of Akt/protein kinase B in metabolism EL Whiteman, H Cho, MJ Birnbaum Trends in Endocrinology & Metabolism 13 (10), 444-451, 2002 | 870 | 2002 |
Identification of a novel gene encoding an insulin-responsive glucose transporter protein MJ Birnbaum Cell 57 (2), 305-315, 1989 | 803 | 1989 |
Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development D O’Sullivan, GJW van der Windt, SCC Huang, JD Curtis, CH Chang, ... Immunity 41 (1), 75-88, 2014 | 793 | 2014 |
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. MJ Birnbaum, HC Haspel, OM Rosen Proceedings of the National Academy of Sciences 83 (16), 5784-5788, 1986 | 733 | 1986 |
Role for Akt3/protein kinase Bγ in attainment of normal brain size RM Easton, H Cho, K Roovers, DW Shineman, M Mizrahi, MS Forman, ... Molecular and cellular biology 25 (5), 1869-1878, 2005 | 723 | 2005 |
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 712 | 2015 |