Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator SD O’Donovan, M Lenz, GH Goossens, CJH van der Kallen, ... Scientific reports 9 (1), 9388, 2019 | 34 | 2019 |
A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data SD O’Donovan, M Lenz, RG Vink, NJT Roumans, TMCM de Kok, ... PLoS computational biology 15 (10), e1007400, 2019 | 18 | 2019 |
Transcriptomic signature of fasting in human adipose tissue M Defour, CCJR Michielsen, SD O’donovan, LA Afman, S Kersten Physiological genomics 52 (10), 451-467, 2020 | 17 | 2020 |
Personalized computational model quantifies heterogeneity in postprandial responses to oral glucose challenge B Erdős, B van Sloun, ME Adriaens, SD O’Donovan, D Langin, A Astrup, ... PLoS Computational Biology 17 (3), e1008852, 2021 | 15 | 2021 |
Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes SD O’Donovan, K Driessens, D Lopatta, F Wimmenauer, A Lukas, ... Plos one 15 (8), e0236392, 2020 | 5 | 2020 |
Analysis of high-dimensional metabolomics data with complex temporal dynamics using RM-ASCA+ B Erdős, JA Westerhuis, ME Adriaens, SD O’Donovan, R Xie, ... PLOS Computational Biology 19 (6), e1011221, 2023 | 4 | 2023 |
E-DES-PROT: A novel computational model to describe the effects of amino acids and protein on postprandial glucose and insulin dynamics in humans B van Sloun, GH Goossens, B Erdõs, SD O’Donovan, CM Singh-Povel, ... Iscience 26 (3), 2023 | 4 | 2023 |
Quantifying the contribution of triglycerides to metabolic resilience through the mixed meal model SD O’Donovan, B Erdős, DM Jacobs, AJ Wanders, EL Thomas, JD Bell, ... Iscience 25 (11), 2022 | 4 | 2022 |
Deep learning methods to translate gene expression changes induced in vitro in rat hepatocytes to human in vivo TM de Kok, S O'Donovan, M Lenz, F Wimmenauer, A Lukas, J Neeven, ... Toxicology Letters 314, S170-S170, 2019 | 2 | 2019 |
Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study B Erdős, B van Sloun, GH Goossens, SD O’Donovan, BE de Galan, ... Plos one 18 (7), e0285820, 2023 | 1 | 2023 |
Quantifying the effect of nutritional interventions on metabolic resilience using personalized computational models SD O’Donovan, M Rundle, EL Thomas, JD Bell, G Frost, DM Jacobs, ... Iscience 27 (4), 2024 | | 2024 |
Leveraging continuous glucose monitoring for personalized modeling of insulin-regulated glucose metabolism B Erdős, SD O’Donovan, ME Adriaens, A Gijbels, I Trouwborst, KM Jardon, ... Scientific Reports 14 (1), 8037, 2024 | | 2024 |
Physiology-informed regularization enables training of universal differential equation systems for biological applications M de Rooij, B Erdos, N van Riel, S O'Donovan bioRxiv, 2024.05. 28.596164, 2024 | | 2024 |
Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data SD O’Donovan, R Cavill, F Wimmenauer, A Lukas, T Stumm, E Smirnov, ... Plos one 18 (11), e0292030, 2023 | | 2023 |
Accelerating Dynamic Modelling and Parameter Estimation in Biology using the Julia Programming Language M de Rooij, B Erdős, NAW van Riel, S O'Donovan | | 2023 |
From Population to Personalized Physiological Models: Parameter Estimation Approaches in a Physiology-Constrained Simulation Study R de Vries, S O'Donovan, NAW van Riel | | 2023 |
The Mixed Meal Model: quantifying the contribution of 1 triglycerides to metabolic resilience. SD O’Donovan, B Erdős, DM Jacobs, AJ Wanders, EL Thomas, JD Bell, ... iScience 25 (11), 2022 | | 2022 |
Metabolic Reprogramming of the Innate Immune System S O'Donovan, N Valenbreder, NAW van Riel 8th Dutch Bioinformatics & Systems Biology Conference, 2022 | | 2022 |
The Mixed Meal Model; towards precision nutrition in overweight and obesity. S O'Donovan, ICW Arts, L Afman, NAW van Riel 8th Dutch Bioinformatics & Systems Biology Conference, 2022 | | 2022 |
The M3al Model; towards precision nutrition in overweight an obesity. S O'Donovan, R de Vries, ICW Arts, NAW van Riel, L Afman NuGO week 2021, 2021 | | 2021 |