| Genetic and transcriptional evolution alters cancer cell line drug response U Ben-David, B Siranosian, G Ha, H Tang, Y Oren, K Hinohara, ... Nature 560 (7718), 325-330, 2018 | 837 | 2018 |
| Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration JM McFarland, ZV Ho, G Kugener, JM Dempster, PG Montgomery, ... Nature Communications 9 (1), 2018 | 341 | 2018 |
| Extracting biological insights from the project achilles genome-scale CRISPR screens in cancer cell lines JM Dempster, J Rossen, M Kazachkova, J Pan, G Kugener, DE Root, ... BioRxiv, 720243, 2019 | 312 | 2019 |
| Integrated cross-study datasets of genetic dependencies in cancer C Pacini, JM Dempster, I Boyle, E Gonçalves, H Najgebauer, E Karakoc, ... Nature communications 12 (1), 1661, 2021 | 207 | 2021 |
| Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ... Nature communications 10 (1), 5817, 2019 | 196 | 2019 |
| Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects JM Dempster, I Boyle, F Vazquez, DE Root, JS Boehm, WC Hahn, ... Genome biology 22, 1-23, 2021 | 193 | 2021 |
| Noncanonical open reading frames encode functional proteins essential for cancer cell survival JR Prensner, OM Enache, V Luria, K Krug, KR Clauser, JM Dempster, ... Nature biotechnology 39 (6), 697-704, 2021 | 107 | 2021 |
| A first-generation pediatric cancer dependency map NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ... Nature genetics 53 (4), 529-538, 2021 | 101 | 2021 |
| Targetable vulnerabilities in T-and NK-cell lymphomas identified through preclinical models SY Ng, N Yoshida, AL Christie, M Ghandi, NV Dharia, J Dempster, ... Nature communications 9 (1), 2024, 2018 | 95 | 2018 |
| Synthetic lethal interaction of SHOC2 depletion with MEK inhibition in RAS-driven cancers R Sulahian, JJ Kwon, KH Walsh, E Pailler, TL Bosse, M Thaker, ... Cell reports 29 (1), 118-134. e8, 2019 | 75 | 2019 |
| Understanding degenerate ground states of a protected quantum circuit in the presence of disorder JM Dempster, B Fu, DG Ferguson, DI Schuster, J Koch Physical Review B 90 (9), 094518, 2014 | 67 | 2014 |
| Aggregation of heterogeneously charged colloids JM Dempster, M Olvera de la Cruz Acs Nano 10 (6), 5909-5915, 2016 | 51 | 2016 |
| Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer DP Bondeson, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, ... Nature cancer 3 (6), 681-695, 2022 | 32 | 2022 |
| Selective modulation of a pan-essential protein as a therapeutic strategy in cancer CF Malone, NV Dharia, G Kugener, AB Forman, MV Rothberg, ... Cancer discovery 11 (9), 2282-2299, 2021 | 29 | 2021 |
| BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022 | 28 | 2022 |
| Paramagnetic filaments in a fast precessing field: Planar versus helical conformations P Vázquez-Montejo, JM Dempster, MO de la Cruz Physical Review Materials 1 (6), 064402, 2017 | 27 | 2017 |
| Gene expression has more power for predicting in vitro cancer cell vulnerabilities than genomics JM Dempster, JM Krill-Burger, JM McFarland, A Warren, JS Boehm, ... BioRxiv, 2020.02. 21.959627, 2020 | 26 | 2020 |
| Contractile actuation and dynamical gel assembly of paramagnetic filaments in fast precessing fields JM Dempster, P Vázquez-Montejo, M Olvera de la Cruz Physical Review E 95 (5), 052606, 2017 | 25 | 2017 |
| Comparative optimization of combinatorial CRISPR screens R Li, O Klingbeil, D Monducci, MJ Young, DJ Rodriguez, Z Bayyat, ... Nature Communications 13 (1), 2469, 2022 | 21 | 2022 |
| Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration. Nat Commun. 2018; 9 (1): 4610 JM McFarland, ZV Ho, G Kugener, JM Dempster, PG Montgomery, ... DOI: https://doi. org/10.1038/s41467-018-06916-5. PMID: https://www. ncbi …, 0 | 20 | |
Francisca VazquezDirector, Cancer Dependency Map, Broad Institute在 broadinstitute.org 的电子邮件经过验证
