关注
Matthew D. DeMars II
Matthew D. DeMars II
Research scientist, RevivBio
在 revivbio.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Controlled Oxidation of Remote sp3 C–H Bonds in Artemisinin via P450 Catalysts with Fine-Tuned Regio- and Stereoselectivity
K Zhang, BM Shafer, MD Demars, HA Stern, R Fasan
Journal of the American Chemical Society 134 (45), 18695-18704, 2012
2032012
Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C H Functionalization
AN Lowell, MD DeMars, ST Slocum, F Yu, K Anand, JA Chemler, ...
Journal of the American Chemical Society 139 (23), 7913-7920, 2017
832017
Regiodivergent glycosylations of 6-deoxy-erythronolide B and oleandomycin-derived macrolactones enabled by chiral acid catalysis
JH Tay, AJ Argüelles, MD DeMars, PM Zimmerman, DH Sherman, ...
Journal of the American Chemical Society 139 (25), 8570-8578, 2017
72*2017
Synthesis of diverse 11-and 12-membered macrolactones from a common linear substrate using a single biocatalyst
MM Gilbert, MD DeMars, S Yang, JM Grandner, S Wang, H Wang, ...
ACS Central Science 3 (12), 1304-1310, 2017
262017
Computational-based mechanistic study and engineering of cytochrome P450 MycG for selective oxidation of 16-membered macrolide antibiotics
S Yang, MD DeMars, JM Grandner, NM Olson, Y Anzai, DH Sherman, ...
Journal of the American Chemical Society 142 (42), 17981-17988, 2020
192020
Biochemical and structural characterization of MycCI, a versatile P450 biocatalyst from the mycinamicin biosynthetic pathway
MD DeMars, F Sheng, SR Park, AN Lowell, LM Podust, DH Sherman
ACS chemical biology 11 (9), 2642-2654, 2016
162016
Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis
MO Kamileen, MD DeMars, B Hong, Y Nakamura, C Paetz, BR Lichman, ...
Journal of the American Chemical Society 144 (43), 19673-19679, 2022
92022
Exploring the molecular basis for substrate specificity in homologous macrolide biosynthetic cytochromes P450
MD DeMars, NL Samora, S Yang, M Garcia-Borràs, JN Sanders, KN Houk, ...
Journal of Biological Chemistry 294 (44), 15947-15961, 2019
72019
Structure and biochemistry of cytochromes P450 involved in the biosynthesis of macrolide antibiotics
M DeMars II
32017
Evolution and diversification of carboxylesterase-like [4+ 2] cyclases in aspidosperma and iboga alkaloid biosynthesis
MD DeMars, SE O’Connor
Proceedings of the National Academy of Sciences 121 (7), e2318586121, 2024
12024
Mechanism and Evolution of [4+ 2] Cyclases in Monoterpene Indole Alkaloid Biosynthesis
MD DeMars, Y Nakamura, MO Kamileen, JN Sanders, C Paetz, KN Houk, ...
The FASEB Journal 36, 2022
2022
Comparative Analysis of Bacterial Cytochromes P450 Involved in the Biosynthesis of 16‐Membered Ring Macrolide Antibiotics
MD DeMars, S Yang, F Sheng, NL Samora, SR Park, AN Lowell, KN Houk, ...
The FASEB Journal 32, 529.4-529.4, 2018
2018
Synthesis of Diverse 11-and 12-Membered Macrolactones from a Common Linear Substrate
MM Gilbert, MD DeMars, S Yang
ACS central science, 3 (12), 2017
2017
Exploring biosynthetic P450s as biocatalysts for multi-functional CH oxidation
J Stachowski, M Demars, D Sherman, J Montgomery
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017
2017
Studying the substrate specificity and reactivity of MycG: A multifunctional enzyme
S Yang, J Grandner, M Demars, D Sherman, K Houk
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Chemoenzymatic methods in the total synthesis of macrolide antibiotics: The 16-membered macrolactone core of tylosin/rosamicin/juvenimicin
A Lowell, S Slocum, A Koch, M DeMars, N Korakavi, J Chemler, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
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