A new glucagon and GLP-1 co-agonist eliminates obesity in rodents JW Day, N Ottaway, JT Patterson, V Gelfanov, D Smiley, J Gidda, ... Nature chemical biology 5 (10), 749-757, 2009 | 683 | 2009 |
Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans B Finan, T Ma, N Ottaway, TD Müller, KM Habegger, KM Heppner, ... Science translational medicine 5 (209), 209ra151-209ra151, 2013 | 603 | 2013 |
Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling SH Lockie, KM Heppner, N Chaudhary, JR Chabenne, DA Morgan, ... Diabetes 61 (11), 2753-2762, 2012 | 251 | 2012 |
Activation of thermogenesis in brown adipose tissue and dysregulated lipid metabolism associated with cancer cachexia in mice M Tsoli, M Moore, D Burg, A Painter, R Taylor, SH Lockie, N Turner, ... Cancer research 72 (17), 4372-4382, 2012 | 177 | 2012 |
Neonatal ghrelin programs development of hypothalamic feeding circuits SM Steculorum, G Collden, B Coupe, S Croizier, S Lockie, ZB Andrews, ... The Journal of clinical investigation 125 (2), 846-858, 2015 | 157 | 2015 |
Ghrelin-induced adiposity is independent of orexigenic effects D Perez-Tilve, K Heppner, H Kirchner, SH Lockie, SC Woods, DL Smiley, ... The FASEB Journal 25 (8), 2814, 2011 | 147 | 2011 |
The temporal pattern of cfos activation in hypothalamic, cortical, and brainstem nuclei in response to fasting and refeeding in male mice Q Wu, MB Lemus, R Stark, JA Bayliss, A Reichenbach, SH Lockie, ... Endocrinology 155 (3), 840-853, 2014 | 127 | 2014 |
Calorie-restricted weight loss reverses high-fat diet-induced ghrelin resistance, which contributes to rebound weight gain in a ghrelin-dependent manner DI Briggs, SH Lockie, Q Wu, MB Lemus, R Stark, ZB Andrews Endocrinology 154 (2), 709-717, 2013 | 94 | 2013 |
A stereological analysis of NPY, POMC, Orexin, GFAP astrocyte, and Iba1 microglia cell number and volume in diet-induced obese male mice MB Lemus, JA Bayliss, SH Lockie, VV Santos, A Reichenbach, R Stark, ... Endocrinology 156 (5), 1701-1713, 2015 | 86 | 2015 |
The endocannabinoid system: role in glucose and energy metabolism R Nogueiras, A Diaz-Arteaga, SH Lockie, DA Velásquez, J Tschop, ... Pharmacological research 60 (2), 93-98, 2009 | 75 | 2009 |
Diet-induced obesity causes ghrelin resistance in reward processing tasks SH Lockie, T Dinan, AJ Lawrence, SJ Spencer, ZB Andrews Psychoneuroendocrinology 62, 114-120, 2015 | 72 | 2015 |
Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice DI Briggs, SH Lockie, J Benzler, Q Wu, R Stark, A Reichenbach, AJ Hoy, ... Endocrinology 155 (7), 2411-2422, 2014 | 72 | 2014 |
The hormonal signature of energy deficit: Increasing the value of food reward SH Lockie, ZB Andrews Molecular metabolism 2 (4), 329-336, 2013 | 57 | 2013 |
G lucagon‐Like Peptide‐1 Receptor in the Brain: Role in Neuroendocrine Control of Energy Metabolism and Treatment Target for Obesity SH Lockie Journal of neuroendocrinology 25 (7), 597-604, 2013 | 47 | 2013 |
Acyl ghrelin acts in the brain to control liver function and peripheral glucose homeostasis in male mice R Stark, A Reichenbach, SH Lockie, C Pracht, Q Wu, A Tups, ZB Andrews Endocrinology 156 (3), 858-868, 2015 | 44 | 2015 |
Des-acyl ghrelin and ghrelin O-acyltransferase regulate hypothalamic-pituitary-adrenal axis activation and anxiety in response to acute stress R Stark, VV Santos, B Geenen, A Cabral, T Dinan, JA Bayliss, SH Lockie, ... Endocrinology 157 (10), 3946-3957, 2016 | 42 | 2016 |
Neural and humoral changes associated with the adjustable gastric band: insights from a rodent model J Kampe, A Stefanidis, SH Lockie, WA Brown, JB Dixon, A Odoi, ... International journal of obesity 36 (11), 1403-1411, 2012 | 38 | 2012 |
Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum A Reichenbach, RE Clarke, R Stark, SH Lockie, M Mequinion, ... Elife 11, e72668, 2022 | 35 | 2022 |
AgRP neurons require carnitine acetyltransferase to regulate metabolic flexibility and peripheral nutrient partitioning A Reichenbach, R Stark, M Mequinion, RRG Denis, JF Goularte, ... Cell reports 22 (7), 1745-1759, 2018 | 32 | 2018 |
Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-induced obese mice ANA Verty, SH Lockie, A Stefanidis, BJ Oldfield International journal of obesity 37 (2), 279-287, 2013 | 32 | 2013 |