| Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation S Melgar, A Karlsson, E Michaëlsson American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (6 …, 2005 | 710 | 2005 |
| The impact of western diet and nutrients on the microbiota and immune response at mucosal interfaces D Statovci, M Aguilera, J MacSharry, S Melgar Frontiers in immunology 8, 838, 2017 | 508 | 2017 |
| Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease S Melgar, L Karlsson, E Rehnström, A Karlsson, H Utkovic, L Jansson, ... International immunopharmacology 8 (6), 836-844, 2008 | 245 | 2008 |
| Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis S Melgar, MMW Yeung, A Bas, G Forsberg, O Suhr, Å Öberg, ... Clinical & Experimental Immunology 134 (1), 127-137, 2003 | 227 | 2003 |
| Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease G Forsberg, O Hernell, S Melgar, A Israelsson, S Hammarström, ... Gastroenterology 123 (3), 667-678, 2002 | 226 | 2002 |
| Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease FJ Ryan, AM Ahern, RS Fitzgerald, EJ Laserna-Mendieta, EM Power, ... Nature communications 11 (1), 1512, 2020 | 223 | 2020 |
| Pattern recognition receptors—molecular orchestrators of inflammation in inflammatory bowel disease D Walsh, J McCarthy, C O’Driscoll, S Melgar Cytokine & growth factor reviews 24 (2), 91-104, 2013 | 193 | 2013 |
| Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggest T helper 1 and cytotoxic functions. C Lundqvist, S Melgar, MM Yeung, S Hammarström, ML Hammarström Journal of immunology (Baltimore, Md.: 1950) 157 (5), 1926-1934, 1996 | 174 | 1996 |
| A prospective metagenomic and metabolomic analysis of the impact of exercise and/or whey protein supplementation on the gut microbiome of sedentary adults O Cronin, W Barton, P Skuse, NC Penney, I Garcia-Perez, EF Murphy, ... MSystems 3 (3), 10.1128/msystems. 00044-18, 2018 | 163 | 2018 |
| Characterisation of mucosal lymphoid aggregates in ulcerative colitis: immune cell phenotype and TcR-γδ expression MMW Yeung, S Melgar, V Baranov, Å Öberg, Å Danielsson, ... Gut 47 (2), 215-227, 2000 | 162 | 2000 |
| Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models MJ O’Neill, L Bourre, S Melgar, CM O’Driscoll Drug discovery today 16 (5-6), 203-218, 2011 | 141 | 2011 |
| IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation SE Russell, RM Horan, AM Stefanska, A Carey, G Leon, M Aguilera, ... Mucosal immunology 9 (5), 1193-1204, 2016 | 136 | 2016 |
| Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis LJ Hall, E Faivre, A Quinlan, F Shanahan, K Nally, S Melgar Digestive diseases and sciences 56, 79-89, 2011 | 136 | 2011 |
| A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression AV Zhdanov, IA Okkelman, FWJ Collins, S Melgar, DB Papkovsky Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (10), 1254-1266, 2015 | 126 | 2015 |
| Research gaps in diet and nutrition in inflammatory bowel disease. A topical review by D-ECCO working group [dietitians of ECCO] R Sigall-Boneh, A Levine, M Lomer, N Wierdsma, P Allan, G Fiorino, ... Journal of Crohn's and Colitis 11 (12), 1407-1419, 2017 | 123 | 2017 |
| Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ... Nature immunology 14 (9), 927-936, 2013 | 113 | 2013 |
| Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production E Miyauchi, J O'Callaghan, LF Buttó, G Hurley, S Melgar, S Tanabe, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 303 (9 …, 2012 | 113 | 2012 |
| TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells JA Woznicki, N Saini, P Flood, S Rajaram, CM Lee, P Stamou, A Skowyra, ... Cell death & disease 12 (10), 864, 2021 | 78 | 2021 |
| The complex role of inflammasomes in the pathogenesis of inflammatory bowel diseases–lessons learned from experimental models M Aguilera, T Darby, S Melgar Cytokine & growth factor reviews 25 (6), 715-730, 2014 | 77 | 2014 |
| Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system J McCarthy, MJ O'neill, L Bourre, D Walsh, A Quinlan, G Hurley, J Ogier, ... Journal of controlled release 168 (1), 28-34, 2013 | 77 | 2013 |
