Crystal structure of a DExx box DNA helicase HS Subramanya, LE Bird, JA Brannigan, DB Wigley Nature 384 (6607), 379-383, 1996 | 553 | 1996 |
Structure of HIV-2 reverse transcriptase at 2.35-Å resolution and the mechanism of resistance to non-nucleoside inhibitors J Ren, LE Bird, PP Chamberlain, GB Stewart-Jones, DI Stuart, ... Proceedings of the National Academy of Sciences 99 (22), 14410-14415, 2002 | 265 | 2002 |
Crystal structure of the site‐specific recombinase, XerD HS Subramanya, LK Arciszewska, RA Baker, LE Bird, DJ Sherratt, ... The EMBO Journal, 1997 | 263 | 1997 |
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside … J Ren, C Nichols, L Bird, P Chamberlain, K Weaver, S Short, DI Stuart, ... Journal of molecular biology 312 (4), 795-805, 2001 | 249 | 2001 |
Functional genetic analysis of mutations implicated in a human speech and language disorder SC Vernes, J Nicod, FM Elahi, JA Coventry, N Kenny, AM Coupe, LE Bird, ... Human molecular genetics 15 (21), 3154-3167, 2006 | 218 | 2006 |
Helicases: a unifying structural theme? LE Bird, HS Subramanya, DB Wigley Current opinion in structural biology 8 (1), 14-18, 1998 | 212 | 1998 |
Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding J Ren, C Nichols, LE Bird, T Fujiwara, H Sugimoto, DI Stuart, ... Journal of Biological Chemistry 275 (19), 14316-14320, 2000 | 172 | 2000 |
Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases: structural and biochemical analyses J Ren, J Diprose, J Warren, RM Esnouf, LE Bird, S Ikemizu, M Slater, ... Journal of Biological Chemistry 275 (8), 5633-5639, 2000 | 170 | 2000 |
Mapping Protein−Protein Interactions within a Stable Complex of DNA Primase and DnaB Helicase from Bacillus stearothermophilus LE Bird, H Pan, P Soultanas, DB Wigley Biochemistry 39 (1), 171-182, 2000 | 123 | 2000 |
Characterisation of Bacillus stearothermophilus PcrA helicase: Evidence against an active rolling mechanism LE Bird, JA Brannigan, HS Subramanya, DB Wigley Nucleic acids research 26 (11), 2686-2693, 1998 | 123 | 1998 |
High throughput construction and small scale expression screening of multi-tag vectors in Escherichia coli LE Bird Methods 55 (1), 29-37, 2011 | 118 | 2011 |
Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms S Sainsbury, L Bird, V Rao, SM Shepherd, DI Stuart, WN Hunter, ... Journal of molecular biology 405 (1), 173-184, 2011 | 114 | 2011 |
Genetic modification of a baculovirus vector for increased expression in insect cells RB Hitchman, RD Possee, AT Crombie, A Chambers, K Ho, E Siaterli, ... Cell biology and toxicology 26, 57-68, 2010 | 113 | 2010 |
Crystal structure of SANOS, a bacterial nitric oxide synthase oxygenase protein from Staphylococcus aureus LE Bird, J Ren, J Zhang, N Foxwell, AR Hawkins, IG Charles, ... Structure 10 (12), 1687-1696, 2002 | 111 | 2002 |
Structure and Assembly of a Trans-Periplasmic Channel for Type IV Pili in Neisseria meningitidis JL Berry, MM Phelan, RF Collins, T Adomavicius, T Tønjum, SA Frye, ... Public Library of Science 8 (9), e1002923, 2012 | 94 | 2012 |
Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2 M Harkiolaki, T Tsirka, M Lewitzky, PC Simister, D Joshi, LE Bird, ... Structure 17 (6), 809-822, 2009 | 88 | 2009 |
Molecular architecture and ligand recognition determinants for T4 RNA ligase K El Omari, J Ren, LE Bird, MK Bona, G Klarmann, SFJ LeGrice, ... Journal of Biological Chemistry 281 (3), 1573-1579, 2006 | 79 | 2006 |
The centromere and promoter factor 1, CPFI, of Saccharomyces cerevisiae modulates gene activity through a family of factors including SPT21, RPD1 (SIN3 … EA McKenzie, NA Kent, SJ Dowell, F Moreno, LE Bird, J Mellor Molecular and General Genetics MGG 240, 374-386, 1993 | 74 | 1993 |
Improved expression of secreted and membrane‐targeted proteins in insect cells RB Hitchman, RD Possee, E Siaterli, KS Richards, AJ Clayton, LE Bird, ... Biotechnology and applied biochemistry 56 (3), 85-93, 2010 | 71 | 2010 |
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1α localization in erythroblasts R Renella, NA Roberts, JM Brown, M De Gobbi, LE Bird, T Hassanali, ... Blood, The Journal of the American Society of Hematology 117 (25), 6928-6938, 2011 | 68 | 2011 |