Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer D Öhlund, A Handly-Santana, G Biffi, E Elyada, AS Almeida, ... Journal of Experimental Medicine 214 (3), 579-596, 2017 | 2093 | 2017 |
Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015 | 2027 | 2015 |
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts E Elyada, M Bolisetty, P Laise, WF Flynn, ET Courtois, RA Burkhart, ... Cancer discovery 9 (8), 1102-1123, 2019 | 1483 | 2019 |
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ... Cell 159 (1), 80-93, 2014 | 1113 | 2014 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 868 | 2018 |
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression L Seifert, G Werba, S Tiwari, NN Giao Ly, S Alothman, D Alqunaibit, ... Nature 532 (7598), 245-249, 2016 | 560 | 2016 |
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis SR Nielsen, V Quaranta, A Linford, P Emeagi, C Rainer, A Santos, ... Nature cell biology 18 (5), 549-560, 2016 | 436 | 2016 |
Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors L Ireland, A Santos, MS Ahmed, C Rainer, SR Nielsen, V Quaranta, ... Cancer research 76 (23), 6851-6863, 2016 | 263 | 2016 |
A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer BT Spike, DD Engle, JC Lin, SK Cheung, J La, GM Wahl Cell stem cell 10 (2), 183-197, 2012 | 262 | 2012 |
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice DD Engle, H Tiriac, KD Rivera, A Pommier, S Whalen, TE Oni, B Alagesan, ... Science 364 (6446), 1156-1162, 2019 | 222 | 2019 |
TLR9 ligation in pancreatic stellate cells promotes tumorigenesis CP Zambirinis, E Levie, S Nguy, A Avanzi, R Barilla, Y Xu, L Seifert, ... Journal of Experimental Medicine 212 (12), 2077-2094, 2015 | 164 | 2015 |
Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer V Quaranta, C Rainer, SR Nielsen, ML Raymant, MS Ahmed, DD Engle, ... Cancer research 78 (15), 4253-4269, 2018 | 144 | 2018 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 91 | |
Pancreatic cancer cell migration and metastasis is regulated by chemokine-biased agonism and bioenergetic signaling I Roy, DM McAllister, E Gorse, K Dixon, CT Piper, NP Zimmerman, ... Cancer research 75 (17), 3529-3542, 2015 | 72 | 2015 |
Model organoids provide new research opportunities for ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, DD Engle, DA Tuveson, H Clevers Molecular & cellular oncology 3 (1), e1014757, 2016 | 71 | 2016 |
p53 mutations change phosphatidylinositol acyl chain composition A Naguib, G Bencze, DD Engle, IIC Chio, T Herzka, K Watrud, S Bencze, ... Cell reports 10 (1), 8-19, 2015 | 64 | 2015 |
Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity YV Wang, M Leblanc, N Fox, JH Mao, KL Tinkum, K Krummel, D Engle, ... Genes & development 25 (13), 1426-1438, 2011 | 61 | 2011 |
Identification of resistance pathways specific to malignancy using organoid models of pancreatic cancer M Ponz-Sarvise, V Corbo, H Tiriac, DD Engle, KK Frese, TE Oni, ... Clinical Cancer Research 25 (22), 6742-6755, 2019 | 56 | 2019 |
SIRT1–NOX4 signaling axis regulates cancer cachexia A Dasgupta, SK Shukla, E Vernucci, RJ King, J Abrego, SE Mulder, ... Journal of Experimental Medicine 217 (7), 2020 | 55 | 2020 |
Altered glycosylation in pancreatic cancer and beyond JC Lumibao, JR Tremblay, J Hsu, DD Engle Journal of Experimental Medicine 219 (6), e20211505, 2022 | 47 | 2022 |