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Dannielle D. Engle
Dannielle D. Engle
Assistant Professor, Salk Institute
在 salk.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
D Öhlund, A Handly-Santana, G Biffi, E Elyada, AS Almeida, ...
Journal of Experimental Medicine 214 (3), 579-596, 2017
20932017
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
20272015
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts
E Elyada, M Bolisetty, P Laise, WF Flynn, ET Courtois, RA Burkhart, ...
Cancer discovery 9 (8), 1102-1123, 2019
14832019
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy
MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins, H Tiriac, ...
Cell 159 (1), 80-93, 2014
11132014
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
Cancer discovery 8 (9), 1112-1129, 2018
8682018
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
L Seifert, G Werba, S Tiwari, NN Giao Ly, S Alothman, D Alqunaibit, ...
Nature 532 (7598), 245-249, 2016
5602016
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
SR Nielsen, V Quaranta, A Linford, P Emeagi, C Rainer, A Santos, ...
Nature cell biology 18 (5), 549-560, 2016
4362016
Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors
L Ireland, A Santos, MS Ahmed, C Rainer, SR Nielsen, V Quaranta, ...
Cancer research 76 (23), 6851-6863, 2016
2632016
A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer
BT Spike, DD Engle, JC Lin, SK Cheung, J La, GM Wahl
Cell stem cell 10 (2), 183-197, 2012
2622012
The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice
DD Engle, H Tiriac, KD Rivera, A Pommier, S Whalen, TE Oni, B Alagesan, ...
Science 364 (6446), 1156-1162, 2019
2222019
TLR9 ligation in pancreatic stellate cells promotes tumorigenesis
CP Zambirinis, E Levie, S Nguy, A Avanzi, R Barilla, Y Xu, L Seifert, ...
Journal of Experimental Medicine 212 (12), 2077-2094, 2015
1642015
Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer
V Quaranta, C Rainer, SR Nielsen, ML Raymant, MS Ahmed, DD Engle, ...
Cancer research 78 (15), 4253-4269, 2018
1442018
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290
H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ...
CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
91
Pancreatic cancer cell migration and metastasis is regulated by chemokine-biased agonism and bioenergetic signaling
I Roy, DM McAllister, E Gorse, K Dixon, CT Piper, NP Zimmerman, ...
Cancer research 75 (17), 3529-3542, 2015
722015
Model organoids provide new research opportunities for ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, DD Engle, DA Tuveson, H Clevers
Molecular & cellular oncology 3 (1), e1014757, 2016
712016
p53 mutations change phosphatidylinositol acyl chain composition
A Naguib, G Bencze, DD Engle, IIC Chio, T Herzka, K Watrud, S Bencze, ...
Cell reports 10 (1), 8-19, 2015
642015
Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity
YV Wang, M Leblanc, N Fox, JH Mao, KL Tinkum, K Krummel, D Engle, ...
Genes & development 25 (13), 1426-1438, 2011
612011
Identification of resistance pathways specific to malignancy using organoid models of pancreatic cancer
M Ponz-Sarvise, V Corbo, H Tiriac, DD Engle, KK Frese, TE Oni, ...
Clinical Cancer Research 25 (22), 6742-6755, 2019
562019
SIRT1–NOX4 signaling axis regulates cancer cachexia
A Dasgupta, SK Shukla, E Vernucci, RJ King, J Abrego, SE Mulder, ...
Journal of Experimental Medicine 217 (7), 2020
552020
Altered glycosylation in pancreatic cancer and beyond
JC Lumibao, JR Tremblay, J Hsu, DD Engle
Journal of Experimental Medicine 219 (6), e20211505, 2022
472022
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