SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies CO Barnes, CA Jette, ME Abernathy, KMA Dam, SR Esswein, HB Gristick, ... Nature 588 (7839), 682-687, 2020 | 1439 | 2020 |
Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies CO Barnes, AP West, KE Huey-Tubman, MAG Hoffmann, NG Sharaf, ... Cell 182 (4), 828-842. e16, 2020 | 769 | 2020 |
Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico DF Robbiani, L Bozzacco, JR Keeffe, R Khouri, PC Olsen, A Gazumyan, ... Cell 169 (4), 597-609. e11, 2017 | 346 | 2017 |
Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site HB Gristick, L von Boehmer, AP West Jr, M Schamber, A Gazumyan, ... Nature structural & molecular biology 23 (10), 906-915, 2016 | 205 | 2016 |
Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller NT Freund, H Wang, L Scharf, L Nogueira, JA Horwitz, Y Bar-On, ... Science translational medicine 9 (373), eaal2144, 2017 | 170 | 2017 |
Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop H Wang, AA Cohen, RP Galimidi, HB Gristick, GJ Jensen, PJ Bjorkman Proceedings of the National Academy of Sciences 113 (46), E7151-E7158, 2016 | 160 | 2016 |
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques A Escolano, HB Gristick, ME Abernathy, J Merkenschlager, R Gautam, ... Nature 570 (7762), 468-473, 2019 | 150 | 2019 |
Restriction of HIV-1 escape by a highly broad and potent neutralizing antibody P Schommers, H Gruell, ME Abernathy, MK Tran, AS Dingens, HB Gristick, ... Cell 180 (3), 471-489. e22, 2020 | 108 | 2020 |
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope CO Barnes, HB Gristick, NT Freund, A Escolano, AY Lyubimov, ... Nature communications 9 (1), 1251, 2018 | 101 | 2018 |
An ACE2 microbody containing a single immunoglobulin Fc domain is a potent inhibitor of SARS-CoV-2 T Tada, C Fan, JS Chen, R Kaur, KA Stapleford, H Gristick, BM Dcosta, ... Cell Reports 33 (12), 2020 | 76 | 2020 |
Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4 HB Gristick, M Rao, JW Chartron, ME Rome, S Shan, WM Clemons Jr nAture structurAl & moleculAr biology 21 (5), 437-442, 2014 | 64 | 2014 |
Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies H Wang, HB Gristick, L Scharf, AP West Jr, RP Galimidi, MS Seaman, ... Elife 6, e27389, 2017 | 59 | 2017 |
Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway ME Rome, US Chio, M Rao, H Gristick, S Shan Proceedings of the National Academy of Sciences 111 (46), E4929-E4935, 2014 | 47 | 2014 |
Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody Z Yang, H Wang, AZ Liu, HB Gristick, PJ Bjorkman Nature structural & molecular biology 26 (12), 1167-1175, 2019 | 45 | 2019 |
Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies CO Barnes, CA Jette, ME Abernathy, KMA Dam, SR Esswein, HB Gristick, ... bioRxiv, 2020 | 37 | 2020 |
Crystal structure of mitochondrial fission complex reveals scaffolding function for mitochondrial division 1 (Mdv1) coiled coil Y Zhang, NC Chan, HB Ngo, H Gristick, DC Chan Journal of Biological Chemistry 287 (13), 9855-9861, 2012 | 31 | 2012 |
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env A Escolano, HB Gristick, R Gautam, AT DeLaitsch, ME Abernathy, Z Yang, ... Science translational medicine 13 (621), eabk1533, 2021 | 27 | 2021 |
Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells MAG Hoffmann, Y Bar-On, Z Yang, HB Gristick, PNP Gnanapragasam, ... Proceedings of the National Academy of Sciences 117 (31), 18719-18728, 2020 | 25 | 2020 |
Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer Z Yang, KMA Dam, MD Bridges, MAG Hoffmann, AT DeLaitsch, ... Nature communications 13 (1), 732, 2022 | 19 | 2022 |
X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer HB Gristick, H Wang, PJ Bjorkman Acta Crystallographica Section D: Structural Biology 73 (10), 822-828, 2017 | 19 | 2017 |