EPA and DHA reduce LPS-induced inflammation responses in HK-2 cells: Evidence for a PPAR-γ–dependent mechanism H Li, XZ Ruan, SH Powis, R Fernando, WY Mon, DC Wheeler, ... Kidney international 67 (3), 867-874, 2005 | 598 | 2005 |
Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease APJ De Vries, P Ruggenenti, XZ Ruan, M Praga, JM Cruzado, IM Bajema, ... The lancet Diabetes & endocrinology 2 (5), 417-426, 2014 | 437 | 2014 |
An update on the lipid nephrotoxicity hypothesis XZ Ruan, Z Varghese, JF Moorhead Nature Reviews Nephrology 5 (12), 713-721, 2009 | 330 | 2009 |
Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice KL Ma, XZ Ruan, SH Powis, Y Chen, JF Moorhead, Z Varghese Hepatology 48 (3), 770-781, 2008 | 296 | 2008 |
CD36 in chronic kidney disease: novel insights and therapeutic opportunities X Yang, DM Okamura, X Lu, Y Chen, J Moorhead, Z Varghese, XZ Ruan Nature Reviews Nephrology 13 (12), 769-781, 2017 | 192 | 2017 |
CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis L Zhao, C Zhang, X Luo, P Wang, W Zhou, S Zhong, Y Xie, Y Jiang, ... Journal of hepatology 69 (3), 705-717, 2018 | 188 | 2018 |
Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation XZ Ruan, Z Varghese, SH Powis, JF Moorhead Kidney international 60 (5), 1716-1725, 2001 | 175 | 2001 |
Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines XZ Ruan, JF Moorhead, JL Tao, KL Ma, DC Wheeler, SH Powis, ... Arteriosclerosis, thrombosis, and vascular biology 26 (5), 1150-1155, 2006 | 169 | 2006 |
Reactive oxygen species generation and atherosclerosis WN Nowak, J Deng, XZ Ruan, Q Xu Arteriosclerosis, thrombosis, and vascular biology 37 (5), e41-e52, 2017 | 157 | 2017 |
CD36 mediated fatty acid-induced podocyte apoptosis via oxidative stress W Hua, H Huang, L Tan, J Wan, H Gui, L Zhao, X Ruan, X Chen, X Du PloS one 10 (5), e0127507, 2015 | 151 | 2015 |
PPAR agonists protect mesangial cells from interleukin 1β-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway XZ Ruan, JF Moorhead, R Fernando, DC Wheeler, SH Powis, Z Varghese Journal of the American Society of Nephrology 14 (3), 593-600, 2003 | 148 | 2003 |
PPARs and the kidney in metabolic syndrome X Ruan, F Zheng, Y Guan American Journal of Physiology-Renal Physiology 294 (5), F1032-F1047, 2008 | 138 | 2008 |
CD36 and lipid metabolism in the evolution of atherosclerosis L Zhao, Z Varghese, JF Moorhead, Y Chen, XZ Ruan British medical bulletin 126 (1), 101-112, 2018 | 135 | 2018 |
CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway [S] Y Li, P Yang, L Zhao, Y Chen, X Zhang, S Zeng, L Wei, Z Varghese, ... Journal of lipid research 60 (4), 844-855, 2019 | 123 | 2019 |
Dysregulation of the low-density lipoprotein receptor pathway is involved in lipid disorder-mediated organ injury Y Zhang, KL Ma, XZ Ruan, BC Liu International journal of biological sciences 12 (5), 569, 2016 | 123 | 2016 |
Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway P Yang, C Su, X Luo, H Zeng, L Zhao, L Wei, X Zhang, Z Varghese, ... Cancer letters 438, 76-85, 2018 | 121 | 2018 |
Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA release J Pan, Z Ou, C Cai, P Li, J Gong, XZ Ruan, K He Cellular Immunology 332, 111-120, 2018 | 114 | 2018 |
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis L Zhao, Y Chen, R Tang, Y Chen, Q Li, J Gong, A Huang, Z Varghese, ... Journal of gastroenterology and hepatology 26 (5), 875-883, 2011 | 108 | 2011 |
The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis X Luo, E Zheng, L Wei, H Zeng, H Qin, X Zhang, M Liao, L Chen, L Zhao, ... Cell death & disease 12 (4), 328, 2021 | 103 | 2021 |
Anti-atherosclerotic effects of sirolimus on human vascular smooth muscle cells KL Ma, XZ Ruan, SH Powis, JF Moorhead, Z Varghese American Journal of Physiology-Heart and Circulatory Physiology 292 (6 …, 2007 | 95 | 2007 |