Neuroprotective effects of CD4+ CD25+ Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer's disease model H Baek, M Ye, GH Kang, C Lee, G Lee, DB Choi, J Jung, H Kim, S Lee, ... Oncotarget 7 (43), 69347, 2016 | 149 | 2016 |
Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling KY Ryu, H Lee, H Woo, RJ Kang, KM Han, HH Park, SM Lee, JY Lee, ... Journal of neuroinflammation 16, 1-36, 2019 | 117 | 2019 |
Donepezil regulates LPS and Aβ-stimulated neuroinflammation through MAPK/NLRP3 inflammasome/STAT3 signaling J Kim, H Lee, SK Park, JH Park, HR Jeong, S Lee, H Lee, E Seol, HS Hoe International journal of molecular sciences 22 (19), 10637, 2021 | 73 | 2021 |
Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking E Kim, Y Lee, HJ Lee, JS Kim, BS Song, JW Huh, SR Lee, SU Kim, ... Biochemical and biophysical research communications 403 (2), 167-171, 2010 | 72 | 2010 |
Ibrutinib modulates Aβ/tau pathology, neuroinflammation, and cognitive function in mouse models of Alzheimer's disease H Lee, SG Jeon, J Kim, RJ Kang, SM Kim, KM Han, HH Park, K Kim, ... Aging Cell 20 (3), e13332, 2021 | 40 | 2021 |
Decreased Interleukin‐4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress H Lee, HJ Park, A Starkweather, K An, I Shim Mediators of Inflammation 2016 (1), 3501905, 2016 | 36 | 2016 |
Diverse structural conversion and aggregation pathways of Alzheimerʼs amyloid-β (1–40) Y Lin, BR Sahoo, D Ozawa, M Kinoshita, J Kang, MH Lim, M Okumura, ... ACS nano 13 (8), 8766-8783, 2019 | 33 | 2019 |
Regorafenib regulates AD pathology, neuroinflammation, and dendritic spinogenesis in cells and a mouse model of AD KM Han, RJ Kang, H Jeon, H Lee, JS Lee, HH Park, S Gak Jeon, K Suk, ... Cells 9 (7), 1655, 2020 | 27 | 2020 |
Nilotinib modulates LPS-induced cognitive impairment and neuroinflammatory responses by regulating P38/STAT3 signaling J Kim, H Lee, JH Park, BY Cha, HS Hoe Journal of Neuroinflammation 19 (1), 187, 2022 | 26 | 2022 |
The novel DYRK1A inhibitor KVN93 regulates cognitive function, amyloid-beta pathology, and neuroinflammation H Lee, H Woo, HE Lee, H Jeon, KY Ryu, J han Nam, SG Jeon, HH Park, ... Free Radical Biology and Medicine 160, 575-595, 2020 | 26 | 2020 |
Idebenone regulates Aβ and LPS-induced neurogliosis and cognitive function through inhibition of NLRP3 inflammasome/IL-1β axis activation H Lee, JH Park, HS Hoe Frontiers in Immunology 13, 749336, 2022 | 23 | 2022 |
Regulation of habenular G-protein gamma 8 on learning and memory via modulation of the central acetylcholine system H Lee, TI Choi, YM Kim, S Lee, B Han, IS Bak, SA Moon, DY Yu, KS Shin, ... Molecular psychiatry 26 (8), 3737-3750, 2021 | 18 | 2021 |
Sedative effect of sophora flavescens and matrine H Lee, S Lee, D Jang, SY Chung, I Shim Biomolecules & Therapeutics 25 (4), 390, 2017 | 17 | 2017 |
The VEGF inhibitor vatalanib regulates AD pathology in 5xFAD mice SG Jeon, H Lee, HH Park, KM Han, HS Hoe Molecular brain 13 (1), 131, 2020 | 13 | 2020 |
White ginseng ameliorates depressive behavior and increases hippocampal 5‐HT level in the stressed ovariectomized rats D Jang, H Lee, K Lee, KR Kim, R Won, SE Lee, I Shim BioMed Research International 2019 (1), 5705232, 2019 | 13 | 2019 |
Idebenone decreases Aβ pathology by modulating RAGE/Caspase-3 signaling and the Aβ degradation enzyme NEP in a mouse model of AD H Lee, HR Jeong, JH Park, HS Hoe Biology 10 (9), 938, 2021 | 10 | 2021 |
Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling H Lee, HS Hoe Pharmacological Research 190, 106725, 2023 | 9 | 2023 |
Reelin and APP Cooperatively Modulate Dendritic Spine Formation In Vitro and In Vivo H Lee, JH Park, JH Trotter, JN Maher, KE Keenoy, YM Jang, Y Lee, JI Kim, ... Experimental Neurobiology 32 (1), 42, 2023 | 5 | 2023 |
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD H Lee, JW Hwang, JH Park, YJ Jeong, JY Jang, HS Hoe Molecular Brain 16 (1), 63, 2023 | 3 | 2023 |
Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β JH Park, JW Hwang, H Lee, GM Jang, YJ Jeong, J Cho, J Seo, HS Hoe Frontiers in Immunology 14, 1150940, 2023 | 2 | 2023 |