EditR: a method to quantify base editing from Sanger sequencing MG Kluesner, DA Nedveck, WS Lahr, JR Garbe, JE Abrahante, ... The CRISPR journal 1 (3), 239-250, 2018 | 372 | 2018 |
TALEN-based gene correction for epidermolysis bullosa MJ Osborn, CG Starker, AN McElroy, BR Webber, MJ Riddle, L Xia, ... Molecular Therapy 21 (6), 1151-1159, 2013 | 327 | 2013 |
Evaluation of TCR gene editing achieved by TALENs, CRISPR/Cas9, and megaTAL nucleases MJ Osborn, BR Webber, F Knipping, C Lonetree, N Tennis, AP DeFeo, ... Molecular Therapy 24 (3), 570-581, 2016 | 261 | 2016 |
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors BR Webber, C Lonetree, MG Kluesner, MJ Johnson, EJ Pomeroy, ... Nature communications 10 (1), 5222, 2019 | 185 | 2019 |
A genetically engineered primary human natural killer cell platform for cancer immunotherapy EJ Pomeroy, JT Hunzeker, MG Kluesner, WS Lahr, BA Smeester, ... Molecular Therapy 28 (1), 52-63, 2020 | 142 | 2020 |
Fanconi anemia gene editing by the CRISPR/Cas9 system MJ Osborn, R Gabriel, BR Webber, AP DeFeo, AN McElroy, J Jarjour, ... Human gene therapy 26 (2), 114-126, 2015 | 125 | 2015 |
Efficient targeted integration directed by short homology in zebrafish and mammalian cells WA Wierson, JM Welker, MP Almeida, CM Mann, DA Webster, ME Torrie, ... Elife 9, e53968, 2020 | 111 | 2020 |
Rapid DNA replication origin licensing protects stem cell pluripotency JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, ... Elife 6, e30473, 2017 | 98 | 2017 |
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome) J Tolar, IH Park, L Xia, CJ Lees, B Peacock, B Webber, RT McElmurry, ... Blood, The Journal of the American Society of Hematology 117 (3), 839-847, 2011 | 96 | 2011 |
CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa BR Webber, MJ Osborn, AN McElroy, K Twaroski, C Lonetree, AP DeFeo, ... NPJ Regenerative medicine 1 (1), 1-11, 2016 | 94 | 2016 |
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments ED Tabdanov, NJ Rodríguez-Merced, AX Cartagena-Rivera, VV Puram, ... Nature communications 12 (1), 2815, 2021 | 90 | 2021 |
Base editor correction of COL7A1 in recessive dystrophic epidermolysis bullosa patient-derived fibroblasts and iPSCs MJ Osborn, GA Newby, AN McElroy, F Knipping, SC Nielsen, MJ Riddle, ... Journal of Investigative Dermatology 140 (2), 338-347. e5, 2020 | 89 | 2020 |
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells MG Kluesner, WS Lahr, C Lonetree, BA Smeester, X Qiu, NJ Slipek, ... Nature communications 12 (1), 2437, 2021 | 76 | 2021 |
Engineering of primary human B cells with CRISPR/Cas9 targeted nuclease MJ Johnson, K Laoharawee, WS Lahr, BR Webber, BS Moriarity Scientific Reports 8 (1), 12144, 2018 | 67 | 2018 |
Aryl hydrocarbon receptor inhibition promotes hematolymphoid development from human pluripotent stem cells MG Angelos, PN Ruh, BR Webber, RH Blum, CD Ryan, L Bendzick, ... Blood, The Journal of the American Society of Hematology 129 (26), 3428-3439, 2017 | 64 | 2017 |
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays M Kurata, NK Wolf, WS Lahr, MT Weg, MG Kluesner, S Lee, K Hui, ... PLoS one 13 (9), e0198714, 2018 | 63 | 2018 |
Intracellular genomic transplant and methods of therapy B Moriarity, B Webber, RS McIvor, M Choudhry, SA Rosenberg, ... US Patent 10,166,255, 2019 | 61 | 2019 |
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade DC Palmer, BR Webber, Y Patel, MJ Johnson, CM Kariya, WS Lahr, ... Med 3 (10), 682-704. e8, 2022 | 48 | 2022 |
Modified cells and methods of therapy B Moriarity, B Webber, M Choudhry, RS McIvor, D Largaespada, ... US Patent 11,147,837, 2021 | 48 | 2021 |
Modified cells and methods of therapy B Moriarity, B Webber, M Choudhry, SA Rosenberg, DC Palmer, ... US Patent 10,406,177, 2019 | 44 | 2019 |