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Lalit K. Golani
Lalit K. Golani
Northeastern University
在 northeastern.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Rapid-acting antidepressants
JM Witkin, AE Martin, LK Golani, NZ Xu, JL Smith
Advances in Pharmacology 86, 47-96, 2019
622019
GABAkines–Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors
A Lippa, MM Poe, JL Smith, X Jin, X Ping, LK Golani, JM Cook, JM Witkin
Pharmacology & therapeutics 234, 108035, 2022
572022
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and …
LK Golani, A Wallace-Povirk, SM Deis, J Wong, J Ke, X Gu, S Raghavan, ...
Journal of medicinal chemistry 59 (17), 7856-7876, 2016
442016
Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α …
LK Golani, C George, S Zhao, S Raghavan, S Orr, A Wallace, MR Wilson, ...
Journal of medicinal chemistry 57 (19), 8152-8166, 2014
372014
The α2, 3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats
JM Witkin, R Cerne, PG Davis, KB Freeman, JM Do Carmo, JK Rowlett, ...
Pharmacology Biochemistry and Behavior 180, 22-31, 2019
332019
The positive allosteric modulator of α2/3-containing GABAA receptors, KRM-II-81, is active in pharmaco-resistant models of epilepsy and reduces hyperexcitability after …
JM Witkin, G Li, LK Golani, W Xiong, JL Smith, X Ping, F Rashid, R Jahan, ...
Journal of Pharmacology and Experimental Therapeutics 372 (1), 83-94, 2020
252020
Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam
MJ Moerke, G Li, LK Golani, J Cook, SS Negus
Behavioural pharmacology 30 (5), 452-461, 2019
192019
The α2, 3-selective potentiators of GABAA receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without …
A Biggerstaff, B Kivell, JL Smith, MY Mian, LK Golani, F Rashid, ...
Pharmacology Biochemistry and Behavior 196, 172996, 2020
182020
Improved synthesis of anxiolytic, anticonvulsant, and antinociceptive α2/α3-GABA (A)-ergic receptor subtype selective ligands as promising agents to treat anxiety, epilepsy …
G Li, LK Golani, R Jahan, F Rashid, JM Cook
Synthesis 50 (20), 4124-4132, 2018
182018
An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors
KR Methuku, X Li, R Cerne, SD Gleason, JM Schkeryantz, V Tiruveedhula, ...
Pharmacology Biochemistry and Behavior 170, 9-13, 2018
172018
Design, synthesis and biological evaluation of novel pyrrolo [2, 3-d] pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors …
LK Golani, F Islam, C O'Connor, AS Dekhne, Z Hou, LH Matherly, ...
Bioorganic & medicinal chemistry 28 (12), 115544, 2020
142020
Papaverine ameliorates prenatal alcohol‐induced experimental attention deficit hyperactivity disorder by regulating neuronal function, inflammation, and oxidative stress
N Sharma, B Sharma, N Dhiman, LK Golani
International Journal of Developmental Neuroscience 81 (1), 71-81, 2021
122021
Imidazodiazepine anticonvulsant, KRM-II-81, produces novel, non-diazepam-like antiseizure effects
DE Knutson, JL Smith, X Ping, X Jin, LK Golani, G Li, ...
ACS Chemical Neuroscience 11 (17), 2624-2637, 2020
112020
GABAA Receptor Subtypes and the Abuse‐Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators
LF Berro, D Rüedi‐Bettschen, JE Cook, LK Golani, G Li, R Jahan, ...
Alcoholism: Clinical and Experimental Research 43 (5), 791-802, 2019
112019
Animal models of fatigue in major depressive disorder
PV Stutz, LK Golani, JM Witkin
Physiology & behavior 199, 300-305, 2019
112019
Involvement of muscarinic receptor mechanisms in antidepressant drug action
JM Witkin, JL Smith, LK Golani, EA Brooks, AE Martin
Advances in pharmacology 89, 311-356, 2020
92020
Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni
P McCusker, MY Mian, G Li, MD Olp, VVNPB Tiruveedhula, F Rashid, ...
PLoS Neglected Tropical Diseases 13 (11), e0007826, 2019
92019
Clinical pharmacological innovation in the treatment of depression
JM Witkin, LK Golani, JL Smith
Expert Review of Clinical Pharmacology 16 (4), 349-362, 2023
82023
Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies
LK Golani, MY Mian, T Ahmed, KP Pandey, P Mondal, D Sharmin, ...
Bioorganic & Medicinal Chemistry Letters 62, 128637, 2022
82022
The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81
JM Witkin, X Ping, C Mouser, X Jin, J Hobbs, VVNPB Tiruveedhula, G Li, ...
Brain research 1722, 146356, 2019
82019
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