| Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias E Passini, C Trovato, P Morissette, F Sannajust, A Bueno‐Orovio, ... British journal of pharmacology 176 (19), 3819-3833, 2019 | 64 | 2019 |
| Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities C Trovato, E Passini, N Nagy, A Varró, N Abi-Gerges, S Severi, ... Journal of molecular and cellular cardiology 142, 24-38, 2020 | 41 | 2020 |
| Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off‐label in the first wave of COVID‐19 A Delaunois, M Abernathy, WD Anderson, KA Beattie, KW Chaudhary, ... Clinical and Translational Science 14 (3), 1133-1146, 2021 | 27 | 2021 |
| The virtual assay software for human in silico drug trials to augment drug cardiac testing E Passini, X Zhou, C Trovato, OJ Britton, A Bueno-Orovio, B Rodriguez Journal of Computational Science 52, 101202, 2021 | 21 | 2021 |
| Cross clinical-experimental-computational qualification of in silico drug trials on human cardiac purkinje cells for proarrhythmia risk prediction C Trovato, M Mohr, F Schmidt, E Passini, B Rodriguez Frontiers in Toxicology 4, 992650, 2022 | 8 | 2022 |
| In silico evaluation of cell therapy in acute versus chronic infarction: role of automaticity, heterogeneity and Purkinje in human LL Riebel, ZJ Wang, H Martinez-Navarro, C Trovato, J Camps, LA Berg, ... Scientific Reports 14 (1), 21584, 2024 | 2 | 2024 |
| Modelling and simulation reveals density-dependent re-entry risk in the infarcted ventricles after stem cell-derived cardiomyocyte delivery LL Riebel, ZJ Wang, H Martinez-Navarro, C Trovato, J Biasetti, ... 2022 Computing in Cardiology (CinC) 498, 1-4, 2022 | 2 | 2022 |
| In silico trials for drug safety and efficacy assessment using a novel human Purkinje fibre model C Trovato, C Dusserre, S Billiald-Desquand, E Passini, B Rodríguez 2020 Computing in Cardiology, 1-4, 2020 | 1 | 2020 |
| Upregulation of the sodium potassium pump current supresses ectopic activity after stem cell delivery in the human-based heart after myocardial infarction L Riebel, Z Wang, H Martinez-Navarro, A Dasi, C Trovato, B Rodriguez European Heart Journal 45 (Supplement_1), ehae666. 3738, 2024 | | 2024 |
| In silico model predicts drug-induced changes on cardiac cellular contractility in simulated populations of human ventricular cardiomyocytes C Trovato, S Longobardi, E Passini, K Beattie, M Holmes, K Chaudhary, ... | | 2024 |
| In silico assessment of drug safety and efficacy using the human cardiac Purkinje Trovatomodel and comparison with experimental data C Trovato, M Mohr, F Schmidt, B Rodriguez, E Passini JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 117, 2022 | | 2022 |
| Applying CiPA paradigm for assessing proarrhythmia risk of Covid-19 current off-label used therapies A Delaunois, S Hebeisen, V Gryshkova, I Lushbough, E Passini, ... Journal of Pharmacological and Toxicological Methods 111, 107042, 2021 | | 2021 |
| Drug testing using a novel in silico human cardiac Purkinje cell model and comparison with experimental data C Trovato, C Dusserre, E Passini, B Rodriguez Journal of Pharmacological and Toxicological Methods 111, 107051, 2021 | | 2021 |
| Evaluation of four in silico biomarkers for drug-induced proarrhythmic risk: COVID-19 off-label therapies case study E Passini, X Zhou, C Trovato, A Delaunois, JP Valentin, A Bueno-Orovio, ... Journal of Pharmacological and Toxicological Methods 111, 107052, 2021 | | 2021 |
| Simulated heterogeneity in purkinje-ventricular electrophysiology following acute myocardial infarction remodelling C Trovato, X Zhou, BR Rodriguez EP Europace 23 (Supplement_3), euab116. 538, 2021 | | 2021 |
| Novel human Purkinje electrophysiology model for drug safety and efficacy mechanistic investigations C Trovato, E Passini, N Nagy, A Varro, N Abi-Gerges, A Ghetti, PE Miller, ... Journal of Pharmacological and Toxicological Methods 105, 106808, 2020 | | 2020 |
| Computational framework for multiscale investigation of pro-arrhythmic mechanisms in the human cardiac Purkinje system C Trovato University of Oxford, 2020 | | 2020 |
| A Novel In Silico Human Cardiac Purkinje Cell Model to Investigate Drug Safety and Efficacy E Passini, C Trovato, A Tissier, N Nagy, A Varro, S Severi, B Rodriguez Journal of Pharmacological and Toxicological Methods 88, 209, 2017 | | 2017 |
| P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs C Trovato, E Passini, A Tissier, N Nagy, A Varro', S Severi, B Rodriguez EP Europace 19 (suppl_3), iii116-iii116, 2017 | | 2017 |
| Dispositivi di ultima generazione per l'immunorivelazione di marcatori proteici in fase solida C Trovato | | |
