| Programmable RNA tracking in live cells with CRISPR/Cas9 DA Nelles, MY Fang, MR O’Connell, JL Xu, SJ Markmiller, JA Doudna, ... Cell 165 (2), 488-496, 2016 | 589 | 2016 |
| Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9 R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ... Cell 170 (5), 899-912. e10, 2017 | 293 | 2017 |
| Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development L Kurian, A Aguirre, I Sancho-Martinez, C Benner, T Hishida, TB Nguyen, ... Circulation 131 (14), 1278-1290, 2015 | 215 | 2015 |
| Intracellular mRNA regulation with self-assembled locked nucleic acid polymer nanoparticles AM Rush, DA Nelles, AP Blum, SA Barnhill, ET Tatro, GW Yeo, ... Journal of the American Chemical Society 136 (21), 7615-7618, 2014 | 65 | 2014 |
| Tracking and manipulating cellular rna via nuclear delivery of crispr/cas9 G Yeo, DA Nelles, M Fang, R Batra US Patent App. 15/359,567, 2017 | 63 | 2017 |
| Applications of Cas9 as an RNA‐programmed RNA‐binding protein DA Nelles, MY Fang, S Aigner, GW Yeo BioEssays 37 (7), 732-739, 2015 | 49 | 2015 |
| The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1 R Batra, DA Nelles, DM Roth, F Krach, CA Nutter, T Tadokoro, JD Thomas, ... Nature biomedical engineering 5 (2), 157-168, 2021 | 46 | 2021 |
| Self-transfecting micellar RNA: modulating nanoparticle cell interactions via high density display of small molecule ligands on micelle coronas A Roloff, DA Nelles, MP Thompson, GW Yeo, NC Gianneschi Bioconjugate chemistry 29 (1), 126-135, 2018 | 29 | 2018 |
| Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9 E Yeo, K Brannan, R Marina, D Nelles US Patent 11,453,891, 2022 | 22 | 2022 |
| Peptide brush polymers for efficient delivery of a gene editing protein to stem cells AP Blum, DA Nelles, FJ Hidalgo, MA Touve, DS Sim, AA Madrigal, ... Angewandte Chemie 131 (44), 15793-15796, 2019 | 22 | 2019 |
| Alternative splicing in stem cell self-renewal and diferentiation DA Nelles, GW Yeo Adv Exp Med Biol 695, 92-104, 2010 | 13 | 2010 |
| Reversal of molecular pathology by RNA-targeting Cas9 in a myotonic dystrophy mouse model R Batra, DA Nelles, F Krach, JD Thomas, L Snjader, SM Blue, S Aigner, ... bioRxiv, 184408, 2017 | 4 | 2017 |
| Compositions and methods for the modulation of adaptive immunity DA Nelles, R Batra, G Yeo US Patent App. 16/434,787, 2019 | 3 | 2019 |
| Tracking and manipulating cellular RNA via nuclear delivery of CRISPR/CAS9 E Yeo, DA Nelles, M Fang, R Batra US Patent 11,667,903, 2023 | 2 | 2023 |
| Rna-targeting knockdown and replacement compositions and methods for use DA Nelles, R Batra US Patent App. 16/926,205, 2021 | 2 | 2021 |
| Fasl immunomodulatory gene therapy compositions and methods for use DA Nelles US Patent App. 17/271,123, 2022 | 1 | 2022 |
| RNA-targeting fusion protein compositions and methods for use DA Nelles, R Batra, E Yeo US Patent 10,822,617, 2020 | 1 | 2020 |
| Unbiased identification of nanoparticle cell uptake mechanism via a genome-wide CRISPR/Cas9 knockout screen ELV Nostrand, SA Barnhill, AA Shishkin, DA Nelles, E Byeon, T Nguyen, ... bioRxiv, 2020.10. 08.332510, 2020 | 1 | 2020 |
| High efficiency trans-splicing for replacement of targeted rna sequences in human cells DA Nelles US Patent App. 18/485,535, 2024 | | 2024 |
| Rna-targeting compositions and methods for treating myotonic dystrophy type 1 DA Nelles, R Batra, D Roth, D Zisoulis, TA Angeline US Patent App. 18/039,812, 2024 | | 2024 |
Gene Yeo PhD MBAProfessor of Cellular and Molecular Medicine at UC San Diego在 ucsd.edu 的电子邮件经过验证
