Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function JI Garaycoechea, GP Crossan, F Langevin, M Daly, MJ Arends, KJ Patel Nature 489 (7417), 571-575, 2012 | 408 | 2012 |
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells JI Garaycoechea, GP Crossan, F Langevin, L Mulderrig, S Louzada, ... Nature 553 (7687), 171-177, 2018 | 371 | 2018 |
Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen LB Pontel, IV Rosado, G Burgos-Barragan, JI Garaycoechea, R Yu, ... Molecular cell 60 (1), 177-188, 2015 | 341 | 2015 |
Why does the bone marrow fail in Fanconi anemia? JI Garaycoechea, KJ Patel Blood 123 (1), 26-34, 2014 | 180 | 2014 |
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair MRG Hodskinson, J Silhan, GP Crossan, JI Garaycoechea, S Mukherjee, ... Molecular cell 54 (3), 472-484, 2014 | 163 | 2014 |
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response L Mulderrig, JI Garaycoechea, ZK Tuong, CL Millington, FA Dingler, ... Nature 600 (7887), 158-163, 2021 | 81 | 2021 |
Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases E Rajendra, JI Garaycoechea, KJ Patel, LA Passmore Nucleic acids research 42 (22), 13736-13748, 2014 | 49 | 2014 |
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements LJ Luquette, MB Miller, Z Zhou, CL Bohrson, Y Zhao, H Jin, D Gulhan, ... Nature genetics 54 (10), 1564-1571, 2022 | 40 | 2022 |
XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways L Mulderrig, JI Garaycoechea PLoS genetics 16 (4), e1008555, 2020 | 19 | 2020 |
Biocatalysed halogenation of nucleobase analogues R Médici, JI Garaycoechea, LA Dettorre, AM Iribarren, ES Lewkowicz Biotechnology letters 33 (10), 1999-2003, 2011 | 18 | 2011 |
A comparative study on phosphotransferase activity of acid phosphatases from Raoultella planticola and Enterobacter aerogenes on nucleosides, sugars, and related compounds R Médici, JI Garaycoechea, AL Valino, CA Pereira, ES Lewkowicz, ... Applied microbiology and biotechnology 98 (7), 3013-3022, 2014 | 13 | 2014 |
Do mutational dynamics in stem cells explain the origin of common cancers? GP Crossan, JI Garaycoechea, KJ Patel Cell stem cell 16 (2), 111-112, 2015 | 9 | 2015 |
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner M Wang, LTL Brandt, X Wang, H Russell, E Mitchell, ... Molecular cell 83 (14), 2417-2433. e7, 2023 | 8 | 2023 |
Pathological consequences of DNA damage in the kidney JI Garaycoechea, C Quinlan, MS Luijsterburg Nature Reviews Nephrology 19 (4), 229-243, 2023 | 6 | 2023 |
[Aldehydes and Fanconi anaemia: the enemy within]. FP Langevin, JI Garaycoechea, GP Crossan, KJ Patel Medecine sciences: M/S 29 (4), 361-364, 2013 | 2 | 2013 |
Aldéhydes et anémie de Fanconi-L’ennemi de l’intérieur FPM Langevin, JI Garaycoechea, GP Crossan, KJ Patel médecine/sciences 29 (4), 361-364, 2013 | | 2013 |
Synthesis of nucleoside and pentose monophosphates by acid phosphatase over-producing whole cells E Lewkowicz, R Medici, JI Garaycoechea, AL Valino, G Canepa, ... New Biotechnology, S124, 2009 | | 2009 |