Modelling insecticide-binding sites in the voltage-gated sodium channel AO O'Reilly, BPS Khambay, MS Williamson, LM Field, BA Wallace, ... Biochemical Journal 396 (2), 255-263, 2006 | 335 | 2006 |
Voltage-gated sodium channels as targets for pyrethroid insecticides LM Field, TG Emyr Davies, AO O’reilly, MS Williamson, BA Wallace European biophysics journal 46, 675-679, 2017 | 176 | 2017 |
Sodium channelopathies and pain A Lampert, AO O’Reilly, P Reeh, A Leffler Pflügers Archiv-European Journal of Physiology 460, 249-263, 2010 | 171 | 2010 |
Mutations in DIIS5 and the DIIS4–S5 linker of Drosophila melanogaster sodium channel define binding domains for pyrethroids and DDT PNR Usherwood, TGE Davies, IR Mellor, AO O’reilly, F Peng, H Vais, ... Febs Letters 581 (28), 5485-5492, 2007 | 129 | 2007 |
Knockdown resistance to DDT and pyrethroids: from target‐site mutations to molecular modelling TGE Davies, AO O'Reilly, LM Field, BA Wallace, MS Williamson Pest Management Science: formerly Pesticide Science 64 (11), 1126-1130, 2008 | 113 | 2008 |
The genetic architecture of target‐site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii CS Clarkson, A Miles, NJ Harding, AO O’Reilly, D Weetman, ... Molecular ecology 30 (21), 5303-5317, 2021 | 93 | 2021 |
Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel AO O’Reilly, E Eberhardt, C Weidner, C Alzheimer, BA Wallace, ... Public Library of Science 7 (7), e41667, 2012 | 92 | 2012 |
Inherited pain: sodium channel Nav1. 7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation M Eberhardt, J Nakajima, AB Klinger, C Neacsu, K Hühne, AO O'Reilly, ... Journal of Biological Chemistry 289 (4), 1971-1980, 2014 | 72 | 2014 |
A point mutation in the glutamate‐gated chloride channel of Plutella xylostella is associated with resistance to abamectin X Wang, R Wang, Y Yang, S Wu, AO O'Reilly, Y Wu Insect molecular biology 25 (2), 116-125, 2016 | 70 | 2016 |
Synchrotron radiation circular dichroism spectroscopy-defined structure of the C-terminal domain of NaChBac and its role in channel assembly AM Powl, AO O’Reilly, AJ Miles, BA Wallace Proceedings of the National Academy of Sciences 107 (32), 14064-14069, 2010 | 54 | 2010 |
Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady … NB Cronin, A O'Reilly, H Duclohier, BA Wallace Journal of Biological Chemistry 278 (12), 10675-10682, 2003 | 54 | 2003 |
Predictive 3D modelling of the interactions of pyrethroids with the voltage‐gated sodium channels of ticks and mites AO O'Reilly, MS Williamson, J González‐Cabrera, A Turberg, LM Field, ... Pest management science 70 (3), 369-377, 2014 | 52 | 2014 |
A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1. 7 channel is disrupted by the erythromelalgia-associated F1449V mutation A Lampert, AO O'Reilly, SD Dib-Hajj, L Tyrrell, BA Wallace, SG Waxman Journal of Biological Chemistry 283 (35), 24118-24127, 2008 | 52 | 2008 |
Effects of deglycosylation of sodium channels on their structure and function NB Cronin, A O'Reilly, H Duclohier, BA Wallace Biochemistry 44 (2), 441-449, 2005 | 50 | 2005 |
The opioid methadone induces a local anaesthetic‐like inhibition of the cardiac Na+ channel, Nav1.5 V Schulze, C Stoetzer, AO O'Reilly, E Eberhardt, N Foadi, J Ahrens, ... British journal of pharmacology 171 (2), 427-437, 2014 | 45 | 2014 |
Tetrameric bacterial sodium channels: characterization of structure, stability, and drug binding G Nurani, M Radford, K Charalambous, AO O’Reilly, NB Cronin, S Haque, ... Biochemistry 47 (31), 8114-8121, 2008 | 38 | 2008 |
Evolution of the Insecticide Target Rdl in African Anopheles Is Driven by Interspecific and Interkaryotypic Introgression X Grau-Bové, S Tomlinson, AO O’Reilly, NJ Harding, A Miles, ... Molecular Biology and Evolution 37 (10), 2900-2917, 2020 | 35 | 2020 |
p53 is an important regulator of CCL2 gene expression X Tang, M Asano, A O'Reilly, A Farquhar, Y Yang, S Amar Current molecular medicine 12 (8), 929-943, 2012 | 33 | 2012 |
An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids JS Amey, AO O’Reilly, MJ Burton, AM Puinean, IR Mellor, IR Duce, ... FEBS letters 589 (5), 598-607, 2015 | 32 | 2015 |
Thermal and chemical unfolding and refolding of a eukaryotic sodium channel K Charalambous, AO O'Reilly, PA Bullough, BA Wallace Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (6), 1279-1286, 2009 | 31 | 2009 |