Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex SY Kim, JM Jeong, SJ Kim, W Seo, MH Kim, WM Choi, W Yoo, JH Lee, ... Nature Communications 8 (1), 2247, 2017 | 209 | 2017 |
Exosome‐mediated activation of toll‐like receptor 3 in stellate cells stimulates interleukin‐17 production by γδ T cells in liver fibrosis W Seo, HS Eun, SY Kim, HS Yi, YS Lee, SH Park, MJ Jang, E Jo, SC Kim, ... Hepatology 64 (2), 616-631, 2016 | 183 | 2016 |
Fructose promotes leaky gut, endotoxemia, and liver fibrosis through ethanol‐inducible cytochrome P450‐2E1–mediated oxidative and nitrative stress YE Cho, DK Kim, W Seo, B Gao, SH Yoo, BJ Song Hepatology 73 (6), 2180-2195, 2021 | 164 | 2021 |
ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles W Seo, Y Gao, Y He, J Sun, H Xu, D Feng, SH Park, YE Cho, A Guillot, ... Journal of hepatology 71 (5), 1000-1011, 2019 | 142 | 2019 |
Interleukin-22 ameliorates acute-on-chronic liver failure by reprogramming impaired regeneration pathways in mice X Xiang, D Feng, S Hwang, T Ren, X Wang, E Trojnar, C Matyas, R Mo, ... Journal of hepatology 72 (4), 736-745, 2020 | 134 | 2020 |
MicroRNA‐223 ameliorates nonalcoholic steatohepatitis and cancer by targeting multiple inflammatory and oncogenic genes in hepatocytes Y He, S Hwang, Y Cai, SJ Kim, M Xu, D Yang, A Guillot, D Feng, W Seo, ... Hepatology 70 (4), 1150-1167, 2019 | 129 | 2019 |
Interleukin‐22 ameliorates neutrophil‐driven nonalcoholic steatohepatitis through multiple targets S Hwang, Y He, X Xiang, W Seo, SJ Kim, J Ma, T Ren, SH Park, Z Zhou, ... Hepatology 72 (2), 412-429, 2020 | 126 | 2020 |
Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223–enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis Y He, RM Rodrigues, X Wang, W Seo, J Ma, S Hwang, Y Fu, E Trojnár, ... The Journal of clinical investigation 131 (3), 2021 | 106 | 2021 |
Mitochondrial double‐stranded RNA in exosome promotes Interleukin‐17 production through toll‐like receptor 3 in alcohol‐associated liver injury JH Lee, YR Shim, W Seo, MH Kim, WM Choi, HH Kim, YE Kim, K Yang, ... Hepatology 72 (2), 609-625, 2020 | 93 | 2020 |
Glutamate signaling in hepatic stellate cells drives alcoholic steatosis WM Choi, HH Kim, MH Kim, R Cinar, HS Yi, HS Eun, SH Kim, YJ Choi, ... Cell metabolism 30 (5), 877-889. e7, 2019 | 76 | 2019 |
Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice HS Yi, YS Lee, JS Byun, W Seo, JM Jeong, O Park, G Duester, T Haseba, ... Hepatology 60 (3), 1044-1053, 2014 | 74 | 2014 |
Hepatic non-parenchymal cells: Master regulators of alcoholic liver disease? W Seo, WI Jeong World journal of gastroenterology 22 (4), 1348, 2016 | 67 | 2016 |
Disulfiram treatment normalizes body weight in obese mice M Bernier, SJ Mitchell, D Wahl, A Diaz, A Singh, W Seo, M Wang, A Ali, ... Cell metabolism 32 (2), 203-214. e4, 2020 | 59 | 2020 |
Adipocyte death preferentially induces liver injury and inflammation through the activation of chemokine (C‐C motif) receptor 2‐positive macrophages and lipolysis SJ Kim, D Feng, A Guillot, S Dai, F Liu, S Hwang, R Parker, W Seo, Y He, ... Hepatology 69 (5), 1965-1982, 2019 | 58 | 2019 |
Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids Y Gao, Z Zhou, T Ren, SJ Kim, Y He, W Seo, A Guillot, Y Ding, R Wu, ... Gut 68 (7), 1311-1322, 2019 | 54 | 2019 |
Protective and Detrimental Roles of p38α Mitogen‐Activated Protein Kinase in Different Stages of Nonalcoholic Fatty Liver Disease S Hwang, X Wang, RM Rodrigues, J Ma, Y He, W Seo, SH Park, SJ Kim, ... Hepatology 72 (3), 873-891, 2020 | 49 | 2020 |
Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice JH Hwang, YS Park, HS Kim, D Kim, SH Lee, CH Lee, SH Lee, JE Kim, ... Journal of Controlled Release 355, 184-198, 2023 | 47 | 2023 |
Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice YE Cho, W Seo, DK Kim, PG Moon, SH Kim, BH Lee, BJ Song, MC Baek Scientific reports 8 (1), 16070, 2018 | 47 | 2018 |
Protective effects of ginsenoside F2 on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation in mice SH Park, W Seo, HS Eun, SY Kim, E Jo, MH Kim, WM Choi, JH Lee, ... Biochemical and biophysical research communications 478 (4), 1713-1719, 2016 | 41 | 2016 |
E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9 RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ... Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022 | 32 | 2022 |