关注
Refaat Hamed
Refaat Hamed
Associate Professor, Assiut University, University of Bradford
在 aun.edu.eg 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The enzymes of β-lactam biosynthesis
RB Hamed, JR Gomez-Castellanos, L Henry, C Ducho, MA McDonough, ...
Natural product reports 30 (1), 21-107, 2013
2382013
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans
W Ge, A Wolf, T Feng, C Ho, R Sekirnik, A Zayer, N Granatino, ...
Nature chemical biology 8 (12), 960-962, 2012
1872012
Mechanisms and structures of crotonase superfamily enzymes–how nature controls enolate and oxyanion reactivity
RB Hamed, ET Batchelar, IJ Clifton, CJ Schofield
Cellular and Molecular Life Sciences 65, 2507-2527, 2008
1342008
Evidence for the slow reaction of hypoxia‐inducible factor prolyl hydroxylase 2 with oxygen
E Flashman, LM Hoffart, RB Hamed, JM Bollinger Jr, C Krebs, ...
The FEBS journal 277 (19), 4089-4099, 2010
1122010
Factor‐inhibiting hypoxia‐inducible factor (FIH) catalyses the post‐translational hydroxylation of histidinyl residues within ankyrin repeat domains
M Yang, R Chowdhury, W Ge, RB Hamed, MA McDonough, ...
FEBS Journal 278 (7), 1086-1097, 2011
892011
Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo
SV Sharma, X Tong, C Pubill-Ulldemolins, C Cartmell, EJA Bogosyan, ...
Nature communications 8 (1), 229, 2017
662017
Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde.
R Hopkinson, R Hamed, N Rose, T Claridge, C Schofield
Chembiochem: a European journal of chemical biology 11 (4), 2010
652010
Iron‐Mediated Cleavage of C C Bonds in Vicinal Tricarbonyl Compounds in Water
J Mecinović, RB Hamed, CJ Schofield
Angewandte Chemie International Edition 48 (15), 2796-2800, 2009
632009
The 2-oxoglutarate-dependent oxygenase JMJD6 catalyses oxidation of lysine residues to give 5S-hydroxylysine residues.
M Mantri, ND Loik, RB Hamed, TD Claridge, JS McCullagh, CJ Schofield
Chembiochem: a European journal of chemical biology 12 (4), 531-534, 2011
612011
Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions
D Rotili, M Altun, RB Hamed, C Loenarz, A Thalhammer, RJ Hopkinson, ...
Chemical Communications 47 (5), 1488-1490, 2011
452011
Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S, 5S)-trans-carboxymethylproline
RB Hamed, ET Batchelar, J Mecinovic, TDW Claridge, CJ Schofield
ChemBioChem 10 (2), 246, 2009
332009
Crotonase catalysis enables flexible production of functionalized prolines and carbapenams
RB Hamed, L Henry, JR Gomez-Castellanos, J Mecinovic, C Ducho, ...
Journal of the American Chemical Society 134 (1), 471-479, 2012
302012
Thioester Hydrolysis and C C Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily
ET Batchelar, RB Hamed, C Ducho, TDW Claridge, MJ Edelmann, ...
Angewandte Chemie International Edition 47 (48), 9322-9325, 2008
302008
Stereoselective C–C bond formation catalysed by engineered carboxymethylproline synthases
RB Hamed, JR Gomez-Castellanos, A Thalhammer, D Harding, C Ducho, ...
Nature chemistry 3 (5), 365-371, 2011
292011
Synthesis of regio-and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis
C Ducho, RB Hamed, ET Batchelar, JL Sorensen, B Odell, CJ Schofield
Organic & Biomolecular Chemistry 7 (13), 2770-2779, 2009
272009
A natural solution to photoprotection and isolation of the potent polyene antibiotic, marinomycin A
CS Bailey, JS Zarins-Tutt, M Agbo, H Gao, A Diego-Taboada, M Gan, ...
Chemical Science 10 (32), 7549-7553, 2019
252019
Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles
RB Hamed, J Mecinović, C Ducho, TDW Claridge, CJ Schofield
Chemical communications 46 (9), 1413-1415, 2010
222010
Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6
M Mantri, CJ Webby, ND Loik, RB Hamed, ML Nielsen, MA McDonough, ...
MedChemComm 3 (1), 80-85, 2012
202012
Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles
TJ Smart, RB Hamed, TDW Claridge, CJ Schofield
Bioorganic Chemistry 94, 103386, 2020
152020
Stereoselective preparation of lipidated carboxymethyl-proline/pipecolic acid derivatives via coupling of engineered crotonases with an alkylmalonyl-CoA synthetase
RB Hamed, L Henry, JR Gomez-Castellanos, A Asghar, J Brem, ...
Organic & biomolecular chemistry 11 (47), 8191-8196, 2013
152013
系统目前无法执行此操作,请稍后再试。
文章 1–20