Covid-19 in critically ill patients in the Seattle region—case series PK Bhatraju, BJ Ghassemieh, M Nichols, R Kim, KR Jerome, AK Nalla, ... New England Journal of Medicine 382 (21), 2012-2022, 2020 | 3191 | 2020 |
Archaic hominin admixture facilitated adaptation to out-of-Africa environments RM Gittelman, JG Schraiber, B Vernot, C Mikacenic, MM Wurfel, JM Akey Current Biology 26 (24), 3375-3382, 2016 | 189 | 2016 |
APOε4 is associated with enhanced in vivo innate immune responses in human subjects SC Gale, L Gao, C Mikacenic, SM Coyle, N Rafaels, TM Dudenkov, ... Journal of allergy and clinical immunology 134 (1), 127-134. e9, 2014 | 179 | 2014 |
Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia C Mikacenic, R Moore, V Dmyterko, TE West, WA Altemeier, WC Liles, ... Critical Care 22, 1-8, 2018 | 149 | 2018 |
Identification of acute kidney injury subphenotypes with differing molecular signatures and responses to vasopressin therapy PK Bhatraju, LR Zelnick, J Herting, R Katz, C Mikacenic, S Kosamo, ... American journal of respiratory and critical care medicine 199 (7), 863-872, 2019 | 133 | 2019 |
Biomarkers of endothelial activation are associated with poor outcome in critical illness C Mikacenic, WO Hahn, BL Price, S Harju-Baker, R Katz, KC Kain, ... PloS one 10 (10), e0141251, 2015 | 115 | 2015 |
Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis JP Reilly, F Wang, TK Jones, JA Palakshappa, BJ Anderson, ... Intensive care medicine 44, 1849-1858, 2018 | 106 | 2018 |
Comparison of clinical features and outcomes in critically ill patients hospitalized with COVID-19 versus influenza NL Cobb, NA Sathe, KI Duan, KP Seitz, MR Thau, CC Sung, ED Morrell, ... Annals of the American Thoracic Society 18 (4), 632-640, 2021 | 99 | 2021 |
Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus C Johansson, JD Wetzel, JP He, C Mikacenic, TS Dermody, BL Kelsall The Journal of experimental medicine 204 (6), 1349-1358, 2007 | 99 | 2007 |
Interleukin-17A is associated with alveolar inflammation and poor outcomes in acute respiratory distress syndrome C Mikacenic, EE Hansen, F Radella, SA Gharib, RD Stapleton, MM Wurfel Critical care medicine 44 (3), 496-502, 2016 | 91 | 2016 |
A case for targeting Th17 cells and IL-17A in SARS-CoV-2 infections M Orlov, PL Wander, ED Morrell, C Mikacenic, MM Wurfel The Journal of Immunology 205 (4), 892-898, 2020 | 84 | 2020 |
Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses C Mikacenic, AP Reiner, TD Holden, DA Nickerson, MM Wurfel Genes & Immunity 14 (1), 52-57, 2013 | 78 | 2013 |
A two-biomarker model predicts mortality in the critically ill with sepsis C Mikacenic, BL Price, S Harju-Baker, DS O’Mahony, C Robinson-Cohen, ... American journal of respiratory and critical care medicine 196 (8), 1004-1011, 2017 | 68 | 2017 |
Alveolar macrophage transcriptional programs are associated with outcomes in acute respiratory distress syndrome ED Morrell, PK Bhatraju, CR Mikacenic, F Radella, AM Manicone, ... American journal of respiratory and critical care medicine 200 (6), 732-741, 2019 | 64 | 2019 |
Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation JH Madenspacher, ED Morrell, KM Gowdy, JG McDonald, BM Thompson, ... JCI insight 5 (11), 2020 | 63 | 2020 |
Plasma sRAGE acts as a genetically regulated causal intermediate in sepsis-associated acute respiratory distress syndrome TK Jones, R Feng, VE Kerchberger, JP Reilly, BJ Anderson, ... American journal of respiratory and critical care medicine 201 (1), 47-56, 2020 | 58 | 2020 |
Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients C Robinson-Cohen, R Katz, BL Price, S Harju-Baker, C Mikacenic, ... Critical Care 20, 1-8, 2016 | 56 | 2016 |
Peripheral and alveolar cell transcriptional programs are distinct in acute respiratory distress syndrome ED Morrell, F Radella, AM Manicone, C Mikacenic, RD Stapleton, ... American journal of respiratory and critical care medicine 197 (4), 528-532, 2018 | 53 | 2018 |
A research agenda for precision medicine in sepsis and acute respiratory distress syndrome: an official American Thoracic Society research statement FA Shah, NJ Meyer, DC Angus, R Awdish, É Azoulay, CS Calfee, ... American journal of respiratory and critical care medicine 204 (8), 891-901, 2021 | 50 | 2021 |
Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome ED Morrell, A Wiedeman, SA Long, SA Gharib, TE West, SJ Skerrett, ... JCI insight 3 (10), 2018 | 46 | 2018 |