Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ... Nature medicine 22 (6), 586-597, 2016 | 1219 | 2016 |
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α ID Mascanfroni, MC Takenaka, A Yeste, B Patel, Y Wu, JE Kenison, ... Nature medicine 21 (6), 638-646, 2015 | 448 | 2015 |
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ... Nature neuroscience 22 (5), 729-740, 2019 | 384 | 2019 |
Complement C3-deficient mice fail to display age-related hippocampal decline Q Shi, KJ Colodner, SB Matousek, K Merry, S Hong, JE Kenison, JL Frost, ... Journal of Neuroscience 35 (38), 13029-13042, 2015 | 349 | 2015 |
Tolerogenic nanoparticles inhibit T cell–mediated autoimmunity through SOCS2 A Yeste, MC Takenaka, ID Mascanfroni, M Nadeau, JE Kenison, B Patel, ... Science signaling 9 (433), ra61-ra61, 2016 | 191 | 2016 |
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation V Rothhammer, JE Kenison, E Tjon, MC Takenaka, KA de Lima, ... Proceedings of the National Academy of Sciences 114 (8), 2012-2017, 2017 | 188 | 2017 |
AHR activation is protective against colitis driven by T cells in humanized mice JA Goettel, R Gandhi, JE Kenison, A Yeste, G Murugaiyan, ... Cell reports 17 (5), 1318-1329, 2016 | 182 | 2016 |
Environmental control of astrocyte pathogenic activities in CNS inflammation MA Wheeler, M Jaronen, R Covacu, SEJ Zandee, G Scalisi, ... Cell 176 (3), 581-596. e18, 2019 | 176 | 2019 |
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39 MS Longhi, M Vuerich, A Kalbasi, JE Kenison, A Yeste, E Csizmadia, ... JCI insight 2 (9), 2017 | 83 | 2017 |
Epitope spreading as an early pathogenic event in pediatric multiple sclerosis FJ Quintana, B Patel, A Yeste, M Nyirenda, J Kenison, R Rahbari, D Fetco, ... Neurology 83 (24), 2219-2226, 2014 | 79 | 2014 |
How the AHR became important in cancer: the role of chronically active AHR in cancer aggression Z Wang, M Snyder, JE Kenison, K Yang, B Lara, E Lydell, K Bennani, ... International Journal of Molecular Sciences 22 (1), 387, 2020 | 70 | 2020 |
Tolerogenic nanoparticles suppress central nervous system inflammation JE Kenison, A Jhaveri, Z Li, N Khadse, E Tjon, S Tezza, D Nowakowska, ... Proceedings of the National Academy of Sciences 117 (50), 32017-32028, 2020 | 69 | 2020 |
Identification of environmental factors that promote intestinal inflammation LM Sanmarco, CC Chao, YC Wang, JE Kenison, Z Li, JM Rone, ... Nature 611 (7937), 801-809, 2022 | 58 | 2022 |
The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation JE Kenison, Z Wang, K Yang, M Snyder, FJ Quintana, DH Sherr Proceedings of the National Academy of Sciences 118 (19), e2012692118, 2021 | 49 | 2021 |
System-wide analysis of the T cell response R Covacu, H Philip, M Jaronen, J Almeida, JE Kenison, S Darko, ... Cell reports 14 (11), 2733-2744, 2016 | 44 | 2016 |
Detection of aryl hydrocarbon receptor agonists in human samples V Rothhammer, DM Borucki, JE Kenison, P Hewson, Z Wang, R Bakshi, ... Scientific reports 8 (1), 4970, 2018 | 31 | 2018 |
Aryl hydrocarbon receptor activation in astrocytes by laquinimod ameliorates autoimmune inflammation in the CNS V Rothhammer, JE Kenison, Z Li, E Tjon, MC Takenaka, CC Chao, ... Neurology: Neuroimmunology & Neuroinflammation 8 (2), e946, 2021 | 29 | 2021 |
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells LM Sanmarco, JM Rone, CM Polonio, G Fernandez Lahore, F Giovannoni, ... Nature 620 (7975), 881-889, 2023 | 27 | 2023 |
A cell-based drug delivery platform for treating central nervous system inflammation O Levy, V Rothhammer, I Mascanfroni, Z Tong, R Kuai, M De Biasio, ... Journal of Molecular Medicine 99, 663-671, 2021 | 11 | 2021 |
Therapeutic induction of antigen-specific immune tolerance JE Kenison, NA Stevens, FJ Quintana Nature Reviews Immunology 24 (5), 338-357, 2024 | 7 | 2024 |