Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma SA Lee, SY Lee, IH Cho, MA Oh, ES Kang, YB Kim, WD Seo, S Choi, ... The Journal of clinical investigation 118 (4), 1354-1366, 2008 | 141 | 2008 |
O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells ES Kang, D Han, J Park, TK Kwak, MA Oh, SA Lee, S Choi, ZY Park, ... Experimental cell research 314 (11-12), 2238-2248, 2008 | 133 | 2008 |
Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells N Thapa, Y Sun, M Schramp, S Choi, K Ling, RA Anderson Developmental cell 22 (1), 116-130, 2012 | 123 | 2012 |
Agonist-stimulated phosphatidylinositol-3, 4, 5-trisphosphate generation by scaffolded phosphoinositide kinases S Choi, AC Hedman, S Sayedyahossein, N Thapa, DB Sacks, ... Nature cell biology 18 (12), 1324-1335, 2016 | 121 | 2016 |
Emerging roles of PtdIns(4,5)P2 – beyond the plasma membrane X Tan, N Thapa, S Choi, RA Anderson Journal of cell science 128 (22), 4047-4056, 2015 | 106 | 2015 |
PIP kinases define PI4, 5P2 signaling specificity by association with effectors S Choi, N Thapa, X Tan, AC Hedman, RA Anderson Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 87 | 2015 |
IQGAP1 is a novel phosphatidylinositol 4, 5 bisphosphate effector in regulation of directional cell migration S Choi, N Thapa, AC Hedman, Z Li, DB Sacks, RA Anderson The EMBO journal 32 (19), 2617-2630, 2013 | 84 | 2013 |
A nuclear phosphoinositide kinase complex regulates p53 S Choi, M Chen, VL Cryns, RA Anderson Nature cell biology 21 (4), 462-475, 2019 | 83 | 2019 |
PtdIns (4, 5) P2 signaling regulates ATG14 and autophagy X Tan, N Thapa, Y Liao, S Choi, RA Anderson Proceedings of the National Academy of Sciences 113 (39), 10896-10901, 2016 | 74 | 2016 |
Blockade of four‐transmembrane L6 family member 5 (TM4SF5)‐mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative SA Lee, HW Ryu, YM Kim, S Choi, MJ Lee, TK Kwak, HJ Kim, M Cho, ... Hepatology 49 (4), 1316-1325, 2009 | 73 | 2009 |
Cooperation between integrin α5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity S Choi, SA Lee, TK Kwak, HJ Kim, MJ Lee, SK Ye, SH Kim, S Kim, JW Lee Blood, The Journal of the American Society of Hematology 113 (8), 1845-1855, 2009 | 67 | 2009 |
Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition M Kang, S Choi, SJ Jeong, SA Lee, TK Kwak, H Kim, O Jung, MS Lee, ... Biochemical Journal 443 (3), 691-700, 2012 | 66 | 2012 |
Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase· c-Src complex YB Kim, S Choi, MC Choi, MA Oh, SA Lee, M Cho, K Mizuno, SH Kim, ... Journal of biological chemistry 283 (15), 10089-10096, 2008 | 64 | 2008 |
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells O Jung, S Choi, SB Jang, SA Lee, ST Lim, YJ Choi, HJ Kim, DH Kim, ... Journal of cell science 125 (24), 5960-5973, 2012 | 58 | 2012 |
Phosphatidylinositol 3-kinase signalling is spatially organized at endosomal compartments by microtubule-associated protein 4 N Thapa, M Chen, HT Horn, S Choi, T Wen, RA Anderson Nature cell biology 22 (11), 1357-1370, 2020 | 56 | 2020 |
IQGAP1 is a phosphoinositide effector and kinase scaffold S Choi, RA Anderson Advances in biological regulation 60, 29-35, 2016 | 52 | 2016 |
A p53–phosphoinositide signalosome regulates nuclear AKT activation M Chen, S Choi, T Wen, C Chen, N Thapa, JH Lee, VL Cryns, ... Nature cell biology 24 (7), 1099-1113, 2022 | 49 | 2022 |
Phosphatidylinositol phosphate 5-kinase Iγ and phosphoinositide 3-kinase/Akt signaling couple to promote oncogenic growth N Thapa, S Choi, X Tan, T Wise, RA Anderson Journal of Biological Chemistry 290 (30), 18843-18854, 2015 | 46 | 2015 |
The hidden conundrum of phosphoinositide signaling in cancer N Thapa, X Tan, S Choi, PF Lambert, AC Rapraeger, RA Anderson Trends in cancer 2 (7), 378-390, 2016 | 40 | 2016 |
The specificity of EGF-stimulated IQGAP1 scaffold towards the PI3K-Akt pathway is defined by the IQ3 motif M Chen, S Choi, O Jung, T Wen, C Baum, N Thapa, PF Lambert, ... Scientific reports 9 (1), 9126, 2019 | 37 | 2019 |