Patient-derived xenograft models: an emerging platform for translational cancer research M Hidalgo, F Amant, AV Biankin, E Budinská, AT Byrne, C Caldas, ... Cancer discovery 4 (9), 998-1013, 2014 | 1718 | 2014 |
Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy AE O’Connor, WM Gallagher, AT Byrne Photochemistry and photobiology 85 (5), 1053-1074, 2009 | 1452 | 2009 |
Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 681 | 2017 |
Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model AT Byrne, L Ross, J Holash, M Nakanishi, L Hu, JI Hofmann, ... Clinical Cancer Research 9 (15), 5721-5728, 2003 | 432 | 2003 |
Supramolecular photonic therapeutic agents SO McDonnell, MJ Hall, LT Allen, A Byrne, WM Gallagher, DF O'Shea Journal of the American Chemical Society 127 (47), 16360-16361, 2005 | 396 | 2005 |
Human placental vascular development: vasculogenic and angiogenic (branching and nonbranching) transformation is regulated by vascular endothelial growth factor-A, angiopoietin … E Geva, DG Ginzinger, CJ Zaloudek, DH Moore, A Byrne, RB Jaffe The Journal of Clinical Endocrinology & Metabolism 87 (9), 4213-4224, 2002 | 337 | 2002 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell 185 (12), 2184-2199. e16, 2022 | 236 | 2022 |
Bioluminescent imaging: a critical tool in pre‐clinical oncology research K O'Neill, SK Lyons, WM Gallagher, KM Curran, AT Byrne The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010 | 216 | 2010 |
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia SF Fitzpatrick, MM Tambuwala, U Bruning, B Schaible, CC Scholz, ... The Journal of Immunology 186 (2), 1091-1096, 2011 | 203 | 2011 |
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ... Nature genetics 53 (1), 86-99, 2021 | 158 | 2021 |
Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment AT Byrne, AE O'connor, M Hall, J Murtagh, K O'neill, KM Curran, ... British journal of cancer 101 (9), 1565-1573, 2009 | 120 | 2009 |
PDX-MI: minimal information for patient-derived tumor xenograft models TF Meehan, N Conte, T Goldstein, G Inghirami, MA Murakami, S Brabetz, ... Cancer research 77 (21), e62-e66, 2017 | 118 | 2017 |
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells E Hams, SP Saunders, EP Cummins, A O'Connor, MT Tambuwala, ... Shock 36 (3), 295-302, 2011 | 104 | 2011 |
The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy R van der Meel, MH Symons, R Kudernatsch, RJ Kok, RM Schiffelers, ... Drug discovery today 16 (5-6), 219-228, 2011 | 91 | 2011 |
AKT1 E17K mutation profiling in breast cancer: prevalence, concurrent oncogenic alterations, and blood-based detection M Rudolph, T Anzeneder, A Schulz, G Beckmann, AT Byrne, M Jeffers, ... BMC cancer 16, 1-12, 2016 | 85 | 2016 |
Patient-derived xenograft models: an emerging platform for translational cancer research. Cancer Discov. 2014; 4 (9): 998–1013. doi: 10.1158/2159-8290 M Hidalgo, F Amant, AV Biankin, E Budinska, AT Byrne, C Caldas, ... CD-14-0001.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2012 | 79 | 2012 |
The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate S O'Connor, E Szwej, J Nikodinovic-Runic, A O'Connor, AT Byrne, ... Biomaterials 34 (11), 2710-2718, 2013 | 67 | 2013 |
Recent advances in molecular imaging biomarkers in cancer: application of bench to bedside technologies R van der Meel, WM Gallagher, S Oliveira, AE O’Connor, RM Schiffelers, ... Drug discovery today 15 (3-4), 102-114, 2010 | 66 | 2010 |
Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells N O’Donovan, AT Byrne, AE O’Connor, S McGee, WM Gallagher, J Crown Investigational new drugs 29, 752-759, 2011 | 61 | 2011 |