关注
Vaibhav Sidarala
Vaibhav Sidarala
在 med.umich.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mitophagy protects β cells from inflammatory damage in diabetes
V Sidarala, GL Pearson, VS Parekh, B Thompson, L Christen, ...
JCI insight 5 (24), 2020
792020
The regulatory roles of mitogen-activated protein kinase (MAPK) pathways in health and diabetes: lessons learned from the pancreatic β-cell
V Sidarala, A Kowluru
Recent patents on endocrine, metabolic & immune drug discovery 10 (2), 76-84, 2016
682016
Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: evidence for a requisite role of Ras-related C3 botulinum …
V Sidarala, R Veluthakal, K Syeda, C Vlaar, P Newsholme, A Kowluru
Biochemical pharmacology 95 (4), 301-310, 2015
442015
VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells
R Veluthakal, R Tunduguru, DK Arora, V Sidarala, K Syeda, CP Vlaar, ...
Diabetologia 58, 2573-2581, 2015
412015
Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis
V Sidarala, J Zhu, E Levi-D’Ancona, GL Pearson, EC Reck, EM Walker, ...
Nature communications 13 (1), 2340, 2022
402022
NSC23766, a known inhibitor of Tiam1-Rac1 signaling module, prevents the onset of type 1 diabetes in the NOD mouse model
R Veluthakal, V Sidarala, A Kowluru
Cellular Physiology and Biochemistry 39 (2), 760-767, 2016
392016
Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cells
S Khadija, R Veluthakal, V Sidarala, A Kowluru
Apoptosis 19, 1691-1701, 2014
262014
Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells
V Sidarala, A Kowluru
Apoptosis 22, 597-607, 2017
252017
EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells
V Sidarala, R Veluthakal, K Syeda, A Kowluru
Cellular signalling 27 (6), 1159-1167, 2015
202015
Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing
GA Rutter, V Sidarala, BA Kaufman, SA Soleimanpour
Biochemical Journal 480 (11), 773-789, 2023
122023
Clarifying the function of genes at the chromosome 16p13 locus in type 1 diabetes: CLEC16A and DEXI
MA Gingerich, V Sidarala, SA Soleimanpour
Genes & Immunity 21 (2), 79-82, 2020
112020
β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes
S Skovsø, P Overby, J Memar-Zadeh, JTC Lee, JCC Yang, I Shanina, ...
Endocrinology 163 (11), bqac144, 2022
72022
Mitophagy protects beta cells from inflammatory damage in diabetes. JCI Insight. 2020; 5: e141138
V Sidarala, GL Pearson, VS Parekh, B Thompson, L Christen, ...
7
An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy
MA Gingerich, X Liu, B Chai, GL Pearson, MP Vincent, T Stromer, J Zhu, ...
Autophagy 19 (2), 525-543, 2023
62023
Reciprocal regulatory balance within the CLEC16A–RNF41 mitophagy complex depends on an intrinsically disordered protein region
MA Gingerich, J Zhu, B Chai, MP Vincent, N Xie, V Sidarala, NA Kotov, ...
Journal of Biological Chemistry 299 (4), 2023
42023
Mitofusin 1 and 2 regulation of mtDNA content is a critical determinant of glucose homeostasis
V Sidarala, J Zhu, G Pearson, E Reck, B Kaufman, S Soleimanpour
3*2021
Ovarian Cancer Patient-Derived Organoid Models for Pre-Clinical Drug Testing
BE Fashemi, L van Biljon, J Rodriguez, O Graham, M Mullen, D Khabele
JoVE (Journal of Visualized Experiments), e65068, 2023
22023
Mechanisms of pancreatic beta cell dysfunction in diabetes
V Sidarala
Wayne State University, 2016
22016
Complementary Approaches to Interrogate Mitophagy Flux in Pancreatic β-Cells
E Levi-D’Ancona, V Sidarala, SA Soleimanpour
Journal of visualized experiments: JoVE, 2023
12023
287-OR: Traf6 Directs a Noncanonical Role for Innate Immune Signaling in Pancreatic ß-Cells
E LEVI D ANCONA, JIE ZHU, EM WALKER, V SIDARALA, ...
Diabetes 73 (Supplement_1), 2024
2024
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