| RNA drugs and RNA targets for small molecules: principles, progress, and challenges AM Yu, YH Choi, MJ Tu Pharmacological Reviews 72 (4), 862-898, 2020 | 163 | 2020 |
| RNA therapy: Are we using the right molecules? AM Yu, C Jian, HY Allan, MJ Tu Pharmacology & therapeutics 196, 91-104, 2019 | 118 | 2019 |
| MicroRNA pharmacoepigenetics: posttranscriptional regulation mechanisms behind variable drug disposition and strategy to develop more effective therapy AM Yu, Y Tian, MJ Tu, PY Ho, JL Jilek Drug Metabolism and Disposition 44 (3), 308-319, 2016 | 62 | 2016 |
| Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine S Sun, K Wang, H Lei, L Li, M Tu, S Zeng, H Zhou, H Jiang Progress in Neuro-Psychopharmacology and Biological Psychiatry 49, 1-6, 2014 | 60 | 2014 |
| Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth Y Zhao, MJ Tu, YF Yu, WP Wang, QX Chen, JX Qiu, AX Yu, AM Yu Biochemical pharmacology 98 (4), 602-613, 2015 | 57 | 2015 |
| Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity M Tu, S Sun, K Wang, X Peng, R Wang, L Li, S Zeng, H Zhou, H Jiang Toxicology 311 (3), 225-230, 2013 | 55 | 2013 |
| Bioengineered NRF2-siRNA is effective to interfere with NRF2 pathways and improve chemosensitivity of human cancer cells PC Li, MJ Tu, PY Ho, JL Jilek, Z Duan, QY Zhang, AX Yu, AM Yu Drug Metabolism and Disposition 46 (1), 2-10, 2018 | 53 | 2018 |
| Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression X Li, Y Tian, MJ Tu, PY Ho, N Batra, AM Yu Acta Pharmaceutica Sinica B 9 (3), 639-647, 2019 | 51 | 2019 |
| Chimeric microRNA-1291 biosynthesized efficiently in Escherichia coli is effective to reduce target gene expression in human carcinoma cells and improve chemosensitivity MM Li, B Addepalli, MJ Tu, QX Chen, WP Wang, PA Limbach, JM LaSalle, ... Drug Metabolism and Disposition 43 (7), 1129-1136, 2015 | 50 | 2015 |
| Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergistic antiproliferative effects with chemotherapeutics W Yi, MJ Tu, Z Liu, C Zhang, N Batra, AX Yu, AM Yu Acta Pharmaceutica Sinica B 10 (1), 159-170, 2020 | 45 | 2020 |
| MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis MJ Tu, YZ Pan, JX Qiu, EJ Kim, AM Yu Oncotarget 7 (29), 45547, 2016 | 44 | 2016 |
| Bioengineered noncoding RNAs selectively change cellular miRNome profiles for cancer therapy PY Ho, Z Duan, N Batra, JL Jilek, MJ Tu, JX Qiu, Z Hu, T Wun, PN Lara, ... Journal of Pharmacology and Experimental Therapeutics 365 (3), 494-506, 2018 | 43 | 2018 |
| The exposure of luteolin is much lower than that of apigenin in oral administration of Flos Chrysanthemi extract to rats Z Chen, M Tu, S Sun, S Kong, Y Wang, J Ye, L Li, S Zeng, H Jiang Drug metabolism and pharmacokinetics 27 (1), 162-168, 2012 | 42 | 2012 |
| The contribution of human OCT1, OCT3, and CYP3A4 to nitidine chloride–induced hepatocellular toxicity L Li, M Tu, X Yang, S Sun, X Wu, H Zhou, S Zeng, H Jiang Drug Metabolism and Disposition 42 (7), 1227-1234, 2014 | 41 | 2014 |
| Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest Y Zhao, MJ Tu, WP Wang, JX Qiu, AX Yu, AM Yu Scientific reports 6 (1), 26611, 2016 | 40 | 2016 |
| Involvement of organic cation transporter 1 and CYP3A4 in retrorsine-induced toxicity M Tu, L Li, H Lei, Z Ma, Z Chen, S Sun, S Xu, H Zhou, S Zeng, H Jiang Toxicology 322, 34-42, 2014 | 40 | 2014 |
| Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models MJ Tu, PY Ho, QY Zhang, C Jian, JX Qiu, EJ Kim, RJ Bold, FJ Gonzalez, ... Cancer letters 442, 82-90, 2019 | 39 | 2019 |
| Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo QY Zhang, PY Ho, MJ Tu, JL Jilek, QX Chen, S Zeng, AM Yu International journal of pharmaceutics 547 (1-2), 537-544, 2018 | 39 | 2018 |
| Down-regulation of the placental BCRP/ABCG2 transporter in response to hypoxia signaling LN Francois, L Gorczyca, J Du, KM Bircsak, E Yen, X Wen, MJ Tu, AM Yu, ... Placenta 51, 57-63, 2017 | 33 | 2017 |
| A reliable LC-MS/MS method for the quantification of natural amino acids in mouse plasma: method validation and application to a study on amino acid dynamics during … Z Liu, MJ Tu, C Zhang, JL Jilek, QY Zhang, AM Yu Journal of Chromatography B 1124, 72-81, 2019 | 30 | 2019 |
