Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults SF Sorrells, MF Paredes, A Cebrian-Silla, K Sandoval, D Qi, KW Kelley, ... Nature 555 (7696), 377-381, 2018 | 1505 | 2018 |
Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation H Lui, J Zhang, SR Makinson, MK Cahill, KW Kelley, HY Huang, Y Shang, ... Cell 165 (4), 921-935, 2016 | 673 | 2016 |
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development ID Vainchtein, G Chin, FS Cho, KW Kelley, JG Miller, EC Chien, ... Science 359 (6381), 1269-1273, 2018 | 536 | 2018 |
Generation of functional human 3D cortico-motor assembloids J Andersen, O Revah, Y Miura, N Thom, ND Amin, KW Kelley, M Singh, ... Cell 183 (7), 1913-1929. e26, 2020 | 368 | 2020 |
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity AV Molofsky, KW Kelley, HH Tsai, SA Redmond, SM Chang, L Madireddy, ... Nature 509 (7499), 189-194, 2014 | 305 | 2014 |
Maturation and circuit integration of transplanted human cortical organoids O Revah, F Gore, KW Kelley, J Andersen, N Sakai, X Chen, MY Li, F Birey, ... Nature 610 (7931), 319-326, 2022 | 223 | 2022 |
Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth W Qiang, K Kelley, R Tycko Journal of the American Chemical Society 135 (18), 6860-6871, 2013 | 183 | 2013 |
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes KW Kelley, H Nakao-Inoue, AV Molofsky, MC Oldham Nature neuroscience 21 (9), 1171-1184, 2018 | 172 | 2018 |
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency J Zhang, D Velmeshev, K Hashimoto, YH Huang, JW Hofmann, X Shi, ... Nature 588 (7838), 459-465, 2020 | 132 | 2020 |
Human brain organogenesis: Toward a cellular understanding of development and disease KW Kelley, SP Pașca Cell 185 (1), 42-61, 2022 | 126 | 2022 |
Does adult neurogenesis persist in the human hippocampus? MF Paredes, SF Sorrells, A Cebrian-Silla, K Sandoval, D Qi, KW Kelley, ... Cell stem cell 23 (6), 780-781, 2018 | 124 | 2018 |
Kir4. 1-dependent astrocyte-fast motor neuron interactions are required for peak strength KW Kelley, LB Haim, L Schirmer, GE Tyzack, M Tolman, JG Miller, ... Neuron 98 (2), 306-319. e7, 2018 | 118 | 2018 |
Oligodendrocyte-encoded Kir4. 1 function is required for axonal integrity L Schirmer, W Möbius, C Zhao, A Cruz-Herranz, L Ben Haim, C Cordano, ... elife 7, e36428, 2018 | 86 | 2018 |
Expression profiling of Aldh1l1‐precursors in the developing spinal cord reveals glial lineage‐specific genes and direct Sox9‐Nfe2l1 interactions AV Molofsky, SM Glasgow, LS Chaboub, HH Tsai, AT Murnen, KW Kelley, ... Glia 61 (9), 1518-1532, 2013 | 84 | 2013 |
Distinct and separable roles for EZH2 in neurogenic astroglia WW Hwang, RD Salinas, JJ Siu, KW Kelley, RN Delgado, MF Paredes, ... Elife 3, e02439, 2014 | 79 | 2014 |
Secretagogin is expressed by developing neocortical GABAergic neurons in humans but not mice and increases neurite arbor size and complexity CS Raju, J Spatazza, A Stanco, P Larimer, SF Sorrells, KW Kelley, ... Cerebral Cortex 28 (6), 1946-1958, 2018 | 39 | 2018 |
Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment X Meng, D Yao, K Imaizumi, X Chen, KW Kelley, N Reis, MV Thete, ... Nature 622 (7982), 359-366, 2023 | 24 | 2023 |
Generating human neural diversity with a multiplexed morphogen screen in organoids ND Amin, KW Kelley, J Hao, Y Miura, G Narazaki, T Li, P McQueen, ... bioRxiv, 2023.05. 31.541819, 2023 | 10 | 2023 |
CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development X Meng, D Yao, X Chen, KW Kelley, N Reis, MV Thete, S Kulkarni, ... Biorxiv, 2022.09. 06.506845, 2022 | 9 | 2022 |
Astrocytes: the final frontier… KW Kelley, DH Rowitch Neuron 89 (1), 1-2, 2016 | 6 | 2016 |