| Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ... Science 302 (5653), 2141-2144, 2003 | 1830 | 2003 |
| Diverse somatic mutation patterns and pathway alterations in human cancers Z Kan, BS Jaiswal, J Stinson, V Janakiraman, D Bhatt, HM Stern, P Yue, ... Nature 466 (7308), 869-873, 2010 | 1199 | 2010 |
| Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma RL Yauch, GJP Dijkgraaf, B Alicke, T Januario, CP Ahn, T Holcomb, ... Science 326 (5952), 572-574, 2009 | 1012 | 2009 |
| Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma WK Sung, H Zheng, S Li, R Chen, X Liu, Y Li, NP Lee, WH Lee, ... Nature genetics 44 (7), 765-769, 2012 | 984 | 2012 |
| Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer W Chung, HH Eum, HO Lee, KM Lee, HB Lee, KT Kim, HS Ryu, S Kim, ... Nature communications 8 (1), 15081, 2017 | 916 | 2017 |
| Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer K Wang, J Kan, ST Yuen, ST Shi, KM Chu, S Law, TL Chan, Z Kan, ... Nature genetics 43 (12), 1219-1223, 2011 | 860 | 2011 |
| The BioMart community portal: an innovative alternative to large, centralized data repositories D Smedley, S Haider, S Durinck, L Pandini, P Provero, J Allen, O Arnaiz, ... Nucleic acids research 43 (W1), W589-W598, 2015 | 807 | 2015 |
| Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma Z Kan, H Zheng, X Liu, S Li, TD Barber, Z Gong, H Gao, K Hao, ... Genome research 23 (9), 1422-1433, 2013 | 587 | 2013 |
| Gene structure prediction and alternative splicing analysis using genomically aligned ESTs Z Kan, EC Rouchka, WR Gish Genome research 11 (5), 889-900, 2001 | 515 | 2001 |
| Oncogenic ERBB3 mutations in human cancers BS Jaiswal, NM Kljavin, EW Stawiski, E Chan, C Parikh, S Durinck, ... Cancer cell 23 (5), 603-617, 2013 | 407 | 2013 |
| Somatic mutations in p85α promote tumorigenesis through class IA PI3K activation BS Jaiswal, V Janakiraman, NM Kljavin, S Chaudhuri, HM Stern, W Wang, ... Cancer cell 16 (6), 463-474, 2009 | 338 | 2009 |
| Selecting for functional alternative splices in ESTs Z Kan, W Gish Genome research 12 (12), 1837-1845, 2002 | 235 | 2002 |
| Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples S Nacu, W Yuan, Z Kan, D Bhatt, CS Rivers, J Stinson, BA Peters, ... BMC medical genomics 4, 1-22, 2011 | 190 | 2011 |
| Expression of alternatively spliced sodium channel α-subunit genes: unique splicing patterns are observed in dorsal root ganglia CK Raymond, J Castle, P Garrett-Engele, CD Armour, Z Kan, ... Journal of Biological Chemistry 279 (44), 46234-46241, 2004 | 162 | 2004 |
| Coevolution of PDZ domain–ligand interactions analyzed by high-throughput phage display and deep sequencing A Ernst, D Gfeller, Z Kan, S Seshagiri, PM Kim, GD Bader, SS Sidhu Molecular BioSystems 6 (10), 1782-1790, 2010 | 148 | 2010 |
| A comprehensive transcript index of the human genome generated using microarrays and computational approaches EE Schadt, SW Edwards, D GuhaThakurta, D Holder, L Ying, V Svetnik, ... Genome biology 5, 1-17, 2004 | 148 | 2004 |
| Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures Z Kan, Y Ding, J Kim, HH Jung, W Chung, S Lal, S Cho, ... Nature communications 9 (1), 1725, 2018 | 143 | 2018 |
| Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome YH Park, S Lal, JE Lee, YL Choi, J Wen, S Ram, Y Ding, SH Lee, E Powell, ... Nature communications 11 (1), 6175, 2020 | 115 | 2020 |
| Comprehensive characterization of oncogenic drivers in Asian lung adenocarcinoma S Li, YL Choi, Z Gong, X Liu, M Lira, Z Kan, E Oh, J Wang, JC Ting, X Ye, ... Journal of Thoracic Oncology 11 (12), 2129-2140, 2016 | 93 | 2016 |
| Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles Z Kan, PW Garrett-Engele, JM Johnson, JC Castle Nucleic acids research 33 (17), 5659-5666, 2005 | 85 | 2005 |
John C. CastleChief Data Scientist, Monte Rosa Therapeutics在 monterosatx.com 的电子邮件经过验证
