The role of uptake and efflux transporters in the disposition of glucuronide and sulfate conjugates E Järvinen, F Deng, W Kiander, A Sinokki, H Kidron, N Sjöstedt Frontiers in Pharmacology 12, 802539, 2022 | 44 | 2022 |
Clinical and molecular perspectives on inflammation‐mediated regulation of drug metabolism and transport ACD Dunvald, E Järvinen, C Mortensen, TB Stage Clinical Pharmacology & Therapeutics 112 (2), 277-290, 2022 | 33 | 2022 |
Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP E Järvinen, F Deng, H Kidron, M Finel The Journal of Steroid Biochemistry and Molecular Biology 178, 99-107, 2018 | 27 | 2018 |
UGT1A10 is a high activity and important extrahepatic enzyme: why has its role in intestinal glucuronidation been frequently underestimated? J Troberg, E Jarvinen, GB Ge, L Yang, M Finel Molecular Pharmaceutics 14 (9), 2875-2883, 2017 | 27 | 2017 |
Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7 RA Kallionpää, E Järvinen, M Finel The Journal of Steroid Biochemistry and Molecular Biology 154, 104-111, 2015 | 21 | 2015 |
Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity J Troberg, E Järvinen, M Muniz, N Sneitz, J Mosorin, M Hagström, M Finel Drug Metabolism and Disposition 43 (1), 107-118, 2015 | 20 | 2015 |
Human efflux transport of testosterone, epitestosterone and other androgen glucuronides E Järvinen, H Kidron, M Finel The Journal of Steroid Biochemistry and Molecular Biology 197, 105518, 2020 | 15 | 2020 |
Selectivity in the efflux of glucuronides by human transporters: MRP4 is highly active toward 4-methylumbelliferone and 1-naphthol glucuronides, while MRP3 exhibits … E Jarvinen, J Troberg, H Kidron, M Finel Molecular Pharmaceutics 14 (10), 3299-3311, 2017 | 9 | 2017 |
3D spheroid primary human hepatocytes for prediction of cytochrome P450 and drug transporter induction E Järvinen, HS Hammer, O Pötz, M Ingelman‐Sundberg, TB Stage Clinical Pharmacology & Therapeutics 113 (6), 1284-1294, 2023 | 7 | 2023 |
Tutorial: Statistical analysis and reporting of clinical pharmacokinetic studies ACD Dunvald, DB Iversen, ALO Svendsen, K Agergaard, IB Kuhlmann, ... Clinical and Translational Science 15 (8), 1856-1866, 2022 | 7 | 2022 |
Efflux transport of nicotine, cotinine and trans‐3′‐hydroxycotinine glucuronides by human hepatic transporters E Järvinen, N Sjöstedt, JB Koenderink, H Kidron, M Finel Basic & Clinical Pharmacology & Toxicology 125 (6), 490-498, 2019 | 4 | 2019 |
A novel pathogenic UGT1A1 variant in a Sudanese child with type 1 Crigler-Najjar syndrome W Elfar, E Järvinen, W Ji, J Mosorin, AG Sega, AC Iuga, SJ Lobritto, ... Drug Metabolism and Disposition 47 (1), 45-48, 2019 | 4 | 2019 |
Dicloxacillin‐warfarin drug–drug interaction—A register‐based study and in vitro investigations in 3D spheroid primary human hepatocytes E Järvinen, AC Dalgård Dunvald, MT Ernst, HS Hammer, O Pötz, ... British Journal of Clinical Pharmacology 89 (8), 2614-2624, 2023 | 3 | 2023 |
Evaluating drug-drug interaction risk associated with peptide analogues using advanced in vitro systems RA Nørgaard, DK Bhatt, E Järvinen, TB Stage, C Gabel-Jensen, A Galetin, ... Drug Metabolism and Disposition, 2023 | 1 | 2023 |
Population pharmacokinetic modelling of intracellular tacrolimus in stable kidney transplanted patients. K Agergaard, HC Thiesson, J Carstens, M Kjellsson, CE Staatz, ... | | 2024 |
Flucloxacillin is a weak inducer of CYP3A4 in healthy adults and 3D spheroid of primary human hepatocytes DB Iversen, ACD Dunvald, DM Jespersen, F Nielsen, K Brøsen, ... Clinical Pharmacology & Therapeutics 114 (2), 434-445, 2023 | | 2023 |
Human Efflux Transporters in Drug Disposition: in vitro Transport of Glucuronide Metabolites E Järvinen University of Helsinki, 2019 | | 2019 |
Case report by Toce and co‐authors: Have all the reasons for poor morphine glucuronidation been addressed? M Finel, E Järvinen British Journal of Clinical Pharmacology 85 (4), 859, 2019 | | 2019 |
Cell models for studying the interplay between conjugative metabolism and efflux transporters: establishing UGT1A1, UGT2B7 and MRP3 transfected MDCK cell lines E Järvinen | | 2015 |