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Erkka Järvinen
Erkka Järvinen
PhD, Postdoctoral Researcher at the University of Helsinki
在 helsinki.fi 的电子邮件经过验证
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引用次数
引用次数
年份
The role of uptake and efflux transporters in the disposition of glucuronide and sulfate conjugates
E Järvinen, F Deng, W Kiander, A Sinokki, H Kidron, N Sjöstedt
Frontiers in Pharmacology 12, 802539, 2022
442022
Clinical and molecular perspectives on inflammation‐mediated regulation of drug metabolism and transport
ACD Dunvald, E Järvinen, C Mortensen, TB Stage
Clinical Pharmacology & Therapeutics 112 (2), 277-290, 2022
332022
Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP
E Järvinen, F Deng, H Kidron, M Finel
The Journal of Steroid Biochemistry and Molecular Biology 178, 99-107, 2018
272018
UGT1A10 is a high activity and important extrahepatic enzyme: why has its role in intestinal glucuronidation been frequently underestimated?
J Troberg, E Jarvinen, GB Ge, L Yang, M Finel
Molecular Pharmaceutics 14 (9), 2875-2883, 2017
272017
Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7
RA Kallionpää, E Järvinen, M Finel
The Journal of Steroid Biochemistry and Molecular Biology 154, 104-111, 2015
212015
Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity
J Troberg, E Järvinen, M Muniz, N Sneitz, J Mosorin, M Hagström, M Finel
Drug Metabolism and Disposition 43 (1), 107-118, 2015
202015
Human efflux transport of testosterone, epitestosterone and other androgen glucuronides
E Järvinen, H Kidron, M Finel
The Journal of Steroid Biochemistry and Molecular Biology 197, 105518, 2020
152020
Selectivity in the efflux of glucuronides by human transporters: MRP4 is highly active toward 4-methylumbelliferone and 1-naphthol glucuronides, while MRP3 exhibits …
E Jarvinen, J Troberg, H Kidron, M Finel
Molecular Pharmaceutics 14 (10), 3299-3311, 2017
92017
3D spheroid primary human hepatocytes for prediction of cytochrome P450 and drug transporter induction
E Järvinen, HS Hammer, O Pötz, M Ingelman‐Sundberg, TB Stage
Clinical Pharmacology & Therapeutics 113 (6), 1284-1294, 2023
72023
Tutorial: Statistical analysis and reporting of clinical pharmacokinetic studies
ACD Dunvald, DB Iversen, ALO Svendsen, K Agergaard, IB Kuhlmann, ...
Clinical and Translational Science 15 (8), 1856-1866, 2022
72022
Efflux transport of nicotine, cotinine and trans‐3′‐hydroxycotinine glucuronides by human hepatic transporters
E Järvinen, N Sjöstedt, JB Koenderink, H Kidron, M Finel
Basic & Clinical Pharmacology & Toxicology 125 (6), 490-498, 2019
42019
A novel pathogenic UGT1A1 variant in a Sudanese child with type 1 Crigler-Najjar syndrome
W Elfar, E Järvinen, W Ji, J Mosorin, AG Sega, AC Iuga, SJ Lobritto, ...
Drug Metabolism and Disposition 47 (1), 45-48, 2019
42019
Dicloxacillin‐warfarin drug–drug interaction—A register‐based study and in vitro investigations in 3D spheroid primary human hepatocytes
E Järvinen, AC Dalgård Dunvald, MT Ernst, HS Hammer, O Pötz, ...
British Journal of Clinical Pharmacology 89 (8), 2614-2624, 2023
32023
Evaluating drug-drug interaction risk associated with peptide analogues using advanced in vitro systems
RA Nørgaard, DK Bhatt, E Järvinen, TB Stage, C Gabel-Jensen, A Galetin, ...
Drug Metabolism and Disposition, 2023
12023
Population pharmacokinetic modelling of intracellular tacrolimus in stable kidney transplanted patients.
K Agergaard, HC Thiesson, J Carstens, M Kjellsson, CE Staatz, ...
2024
Flucloxacillin is a weak inducer of CYP3A4 in healthy adults and 3D spheroid of primary human hepatocytes
DB Iversen, ACD Dunvald, DM Jespersen, F Nielsen, K Brøsen, ...
Clinical Pharmacology & Therapeutics 114 (2), 434-445, 2023
2023
Human Efflux Transporters in Drug Disposition: in vitro Transport of Glucuronide Metabolites
E Järvinen
University of Helsinki, 2019
2019
Case report by Toce and co‐authors: Have all the reasons for poor morphine glucuronidation been addressed?
M Finel, E Järvinen
British Journal of Clinical Pharmacology 85 (4), 859, 2019
2019
Cell models for studying the interplay between conjugative metabolism and efflux transporters: establishing UGT1A1, UGT2B7 and MRP3 transfected MDCK cell lines
E Järvinen
2015
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