A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity D Pamies, P Barrera, K Block, G Makri, A Kumar, D Wiersma, L Smirnova, ... Altex 34 (3), 362, 2017 | 209 | 2017 |
Consensus report on the future of animal-free systemic toxicity testing M Leist, N Hasiwa, C Rovida, M Daneshian, D Basketter, I Kimber, ... | 182 | 2014 |
Rotenone exerts developmental neurotoxicity in a human brain spheroid model D Pamies, K Block, P Lau, L Gribaldo, CA Pardo, P Barreras, L Smirnova, ... Toxicology and applied pharmacology 354, 101-114, 2018 | 129 | 2018 |
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis L Smirnova, G Harris, J Delp, M Valadares, D Pamies, HT Hogberg, ... Archives of toxicology 90, 2725-2743, 2016 | 114 | 2016 |
Towards an alternative testing strategy for nanomaterials used in nanomedicine: lessons from NanoTEST M Dusinska, S Boland, M Saunders, L Juillerat-Jeanneret, L Tran, ... Nanotoxicology 9 (sup1), 118-132, 2015 | 86 | 2015 |
Sex differences in liver toxicity—do female and male human primary hepatocytes react differently to toxicants in vitro? M Mennecozzi, B Landesmann, T Palosaari, G Harris, M Whelan PloS one 10 (4), e0122786, 2015 | 84 | 2015 |
Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery PEC Leite, MR Pereira, G Harris, D Pamies, LMG Dos Santos, ... Particle and fibre toxicology 16, 1-20, 2019 | 82 | 2019 |
Toward a 3D model of human brain development for studying gene/environment interactions HT Hogberg, J Bressler, KM Christian, G Harris, G Makri, C O'Driscoll, ... Stem Cell Research & Therapy 4, 1-7, 2013 | 77 | 2013 |
Cellular resilience L Smirnova, G Harris, M Leist, T Hartung | 71 | 2015 |
Iron oxide nanoparticle toxicity testing using high-throughput analysis and high-content imaging G Harris, T Palosaari, Z Magdolenova, M Mennecozzi, JM Gineste, ... Nanotoxicology 9 (sup1), 87-94, 2015 | 61 | 2015 |
Antidepressant paroxetine exerts developmental neurotoxicity in an iPSC-derived 3D human brain model X Zhong, G Harris, L Smirnova, V Zufferey, RCS Sá, F Baldino Russo, ... Frontiers in cellular neuroscience 14, 25, 2020 | 60 | 2020 |
t4 workshop report: Quality assurance of metabolomics M Bouhifd, R Beger, T Flynn, L Guo, G Harris, H Hogberg, ... Altex 32 (4), 319, 2015 | 46 | 2015 |
Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone G Harris, M Eschment, SP Orozco, JM McCaffery, R Maclennan, ... Archives of toxicology 92, 2587-2606, 2018 | 37 | 2018 |
3D differentiation of LUHMES cell line to study recovery and delayed neurotoxic effects G Harris, H Hogberg, T Hartung, L Smirnova Current protocols in toxicology 73 (1), 11.23. 1-11.23. 28, 2017 | 34 | 2017 |
Hepatotoxicity screening taking a mode-of-action approach using HepaRG cells and HCA M Mennecozzi, B Landesmann, GA Harris, R Liska, M Whelan Altex Proc 1 (12), 193-204, 2012 | 27 | 2012 |
Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon … D Pamies, MA Sogorb, M Fabbri, L Gribaldo, A Collotta, B Scelfo, ... International journal of molecular sciences 15 (1), 905-926, 2014 | 23 | 2014 |
Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action C Willett, JC Rae, KO Goyak, G Minsavage, C Westmoreland, M Andersen, ... Altex 31 (4), 500, 2014 | 19 | 2014 |
Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2) D Pamies, A Bal-Price, M Fabbri, L Gribaldo, B Scelfo, G Harris, A Collotta, ... Neuroscience 281, 54-67, 2014 | 18 | 2014 |
Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity D Pamies, D Wiersma, ME Katt, L Zhao, J Burtscher, G Harris, L Smirnova, ... Neurobiology of disease 169, 105719, 2022 | 17 | 2022 |
In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment M Chesnut, LS Muñoz, G Harris, D Freeman, L Gama, CA Pardo, ... Frontiers in cellular and infection microbiology 9, 223, 2019 | 17 | 2019 |